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Side-by-side financial comparison of CASS INFORMATION SYSTEMS INC (CASS) and HERON THERAPEUTICS, INC. (HRTX). Click either name above to swap in a different company.

HERON THERAPEUTICS, INC. is the larger business by last-quarter revenue ($40.6M vs $26.2M, roughly 1.5× CASS INFORMATION SYSTEMS INC). CASS INFORMATION SYSTEMS INC runs the higher net margin — 31.3% vs -7.3%, a 38.5% gap on every dollar of revenue. On growth, HERON THERAPEUTICS, INC. posted the faster year-over-year revenue change (-0.5% vs -1.3%). Over the past eight quarters, HERON THERAPEUTICS, INC.'s revenue compounded faster (8.2% CAGR vs -2.8%).

Cass Information Systems Inc is a leading provider of integrated financial automation and information management solutions for enterprises. Its core services cover freight payment processing, utility expense management, commercial payment services, and supporting data analytics tools, helping clients streamline financial workflows, cut operational costs, and gain clearer cross-category spending visibility to support smarter business decisions.

Antibe Therapeutics was a Toronto-based pharmaceutical company that develops pain and inflammation-reducing drugs based on gaseous mediator technology. Antibe was founded by John L. Wallace, also a co-founder of NicOx, the first company to develop drugs utilizing gaseous mediators. Founded in 2009, the company listed on the TSX Venture Exchange in 2013 and was moved to the Toronto Stock Exchange in November 2020. In 2015, Antibe acquired Citagenix, a distributor involved in regenerative medic...

CASS vs HRTX — Head-to-Head

Bigger by revenue
HRTX
HRTX
1.5× larger
HRTX
$40.6M
$26.2M
CASS
Growing faster (revenue YoY)
HRTX
HRTX
+0.8% gap
HRTX
-0.5%
-1.3%
CASS
Higher net margin
CASS
CASS
38.5% more per $
CASS
31.3%
-7.3%
HRTX
Faster 2-yr revenue CAGR
HRTX
HRTX
Annualised
HRTX
8.2%
-2.8%
CASS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CASS
CASS
HRTX
HRTX
Revenue
$26.2M
$40.6M
Net Profit
$8.2M
$-3.0M
Gross Margin
72.6%
Operating Margin
38.1%
0.1%
Net Margin
31.3%
-7.3%
Revenue YoY
-1.3%
-0.5%
Net Profit YoY
78.3%
-180.6%
EPS (diluted)
$0.61
$-0.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CASS
CASS
HRTX
HRTX
Q4 25
$26.2M
$40.6M
Q3 25
$27.4M
$38.2M
Q2 25
$27.6M
$37.2M
Q1 25
$26.8M
$38.9M
Q4 24
$26.5M
$40.8M
Q3 24
$28.1M
$32.8M
Q2 24
$27.6M
$36.0M
Q1 24
$27.7M
$34.7M
Net Profit
CASS
CASS
HRTX
HRTX
Q4 25
$8.2M
$-3.0M
Q3 25
$9.1M
$-17.5M
Q2 25
$8.9M
$-2.4M
Q1 25
$9.0M
$2.6M
Q4 24
$4.6M
$3.7M
Q3 24
$2.9M
$-4.8M
Q2 24
$4.5M
$-9.2M
Q1 24
$7.2M
$-3.2M
Gross Margin
CASS
CASS
HRTX
HRTX
Q4 25
72.6%
Q3 25
68.8%
Q2 25
73.5%
Q1 25
78.3%
Q4 24
74.9%
Q3 24
71.2%
Q2 24
70.8%
Q1 24
75.6%
Operating Margin
CASS
CASS
HRTX
HRTX
Q4 25
38.1%
0.1%
Q3 25
42.3%
-10.7%
Q2 25
22.8%
-4.4%
Q1 25
40.6%
8.1%
Q4 24
19.7%
10.2%
Q3 24
13.4%
-13.6%
Q2 24
20.2%
-17.9%
Q1 24
32.1%
-13.8%
Net Margin
CASS
CASS
HRTX
HRTX
Q4 25
31.3%
-7.3%
Q3 25
33.2%
-45.8%
Q2 25
32.1%
-6.4%
Q1 25
33.5%
6.8%
Q4 24
17.3%
9.0%
Q3 24
10.5%
-14.8%
Q2 24
16.2%
-25.6%
Q1 24
25.8%
-9.1%
EPS (diluted)
CASS
CASS
HRTX
HRTX
Q4 25
$0.61
$-0.01
Q3 25
$0.68
$-0.10
Q2 25
$0.66
$-0.02
Q1 25
$0.66
$0.01
Q4 24
$0.34
$0.02
Q3 24
$0.21
$-0.03
Q2 24
$0.32
$-0.06
Q1 24
$0.52
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CASS
CASS
HRTX
HRTX
Cash + ST InvestmentsLiquidity on hand
$758.4M
$28.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$243.0M
$14.3M
Total Assets
$2.6B
$255.9M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CASS
CASS
HRTX
HRTX
Q4 25
$758.4M
$28.6M
Q3 25
$486.6M
$43.1M
Q2 25
$431.2M
$16.5M
Q1 25
$428.9M
$19.3M
Q4 24
$680.1M
$25.8M
Q3 24
$432.0M
$25.7M
Q2 24
$441.7M
$18.4M
Q1 24
$368.3M
$20.4M
Stockholders' Equity
CASS
CASS
HRTX
HRTX
Q4 25
$243.0M
$14.3M
Q3 25
$243.4M
$14.9M
Q2 25
$240.8M
$-27.3M
Q1 25
$234.2M
$-28.5M
Q4 24
$229.0M
$-33.7M
Q3 24
$237.6M
$-40.0M
Q2 24
$229.9M
$-37.9M
Q1 24
$229.5M
$-33.8M
Total Assets
CASS
CASS
HRTX
HRTX
Q4 25
$2.6B
$255.9M
Q3 25
$2.5B
$248.9M
Q2 25
$2.3B
$232.1M
Q1 25
$2.3B
$235.8M
Q4 24
$2.4B
$233.1M
Q3 24
$2.3B
$220.8M
Q2 24
$2.3B
$218.1M
Q1 24
$2.3B
$217.9M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CASS
CASS
HRTX
HRTX
Operating Cash FlowLast quarter
$4.8M
$-9.2M
Free Cash FlowOCF − Capex
$4.1M
FCF MarginFCF / Revenue
15.8%
Capex IntensityCapex / Revenue
2.7%
0.0%
Cash ConversionOCF / Net Profit
0.59×
TTM Free Cash FlowTrailing 4 quarters
$31.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CASS
CASS
HRTX
HRTX
Q4 25
$4.8M
$-9.2M
Q3 25
$12.3M
$1.3M
Q2 25
$-1.3M
$-10.9M
Q1 25
$21.6M
$-8.9M
Q4 24
$18.6M
$-11.8M
Q3 24
$-198.0K
$3.4M
Q2 24
$10.7M
$-4.6M
Q1 24
$9.8M
$-9.5M
Free Cash Flow
CASS
CASS
HRTX
HRTX
Q4 25
$4.1M
Q3 25
$11.3M
Q2 25
$-2.6M
$-11.1M
Q1 25
$19.0M
$-9.0M
Q4 24
$18.4M
Q3 24
$-2.2M
$2.9M
Q2 24
$7.9M
Q1 24
$6.3M
FCF Margin
CASS
CASS
HRTX
HRTX
Q4 25
15.8%
Q3 25
41.1%
Q2 25
-9.5%
-29.8%
Q1 25
71.0%
-23.1%
Q4 24
69.5%
Q3 24
-8.0%
9.0%
Q2 24
28.6%
Q1 24
22.9%
Capex Intensity
CASS
CASS
HRTX
HRTX
Q4 25
2.7%
0.0%
Q3 25
3.8%
0.0%
Q2 25
4.9%
0.6%
Q1 25
9.6%
0.3%
Q4 24
0.7%
Q3 24
7.2%
1.3%
Q2 24
10.1%
Q1 24
12.6%
Cash Conversion
CASS
CASS
HRTX
HRTX
Q4 25
0.59×
Q3 25
1.35×
Q2 25
-0.15×
Q1 25
2.41×
-3.37×
Q4 24
4.06×
-3.22×
Q3 24
-0.07×
Q2 24
2.38×
Q1 24
1.37×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CASS
CASS

Processing Fees$15.9M61%
Financial Fees$9.9M38%

HRTX
HRTX

CINVANTI$22.9M56%
ZYNRELEF$12.5M31%
Aponvie$3.8M9%
SUSTOL$1.3M3%

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