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Side-by-side financial comparison of CASS INFORMATION SYSTEMS INC (CASS) and NEKTAR THERAPEUTICS (NKTR). Click either name above to swap in a different company.

CASS INFORMATION SYSTEMS INC is the larger business by last-quarter revenue ($26.2M vs $21.8M, roughly 1.2× NEKTAR THERAPEUTICS). CASS INFORMATION SYSTEMS INC runs the higher net margin — 31.3% vs -165.4%, a 196.7% gap on every dollar of revenue. On growth, CASS INFORMATION SYSTEMS INC posted the faster year-over-year revenue change (-1.3% vs -25.3%). CASS INFORMATION SYSTEMS INC produced more free cash flow last quarter ($4.1M vs $-65.0M). Over the past eight quarters, NEKTAR THERAPEUTICS's revenue compounded faster (0.4% CAGR vs -2.8%).

Cass Information Systems Inc is a leading provider of integrated financial automation and information management solutions for enterprises. Its core services cover freight payment processing, utility expense management, commercial payment services, and supporting data analytics tools, helping clients streamline financial workflows, cut operational costs, and gain clearer cross-category spending visibility to support smarter business decisions.

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, e...

CASS vs NKTR — Head-to-Head

Bigger by revenue
CASS
CASS
1.2× larger
CASS
$26.2M
$21.8M
NKTR
Growing faster (revenue YoY)
CASS
CASS
+24.0% gap
CASS
-1.3%
-25.3%
NKTR
Higher net margin
CASS
CASS
196.7% more per $
CASS
31.3%
-165.4%
NKTR
More free cash flow
CASS
CASS
$69.1M more FCF
CASS
$4.1M
$-65.0M
NKTR
Faster 2-yr revenue CAGR
NKTR
NKTR
Annualised
NKTR
0.4%
-2.8%
CASS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CASS
CASS
NKTR
NKTR
Revenue
$26.2M
$21.8M
Net Profit
$8.2M
$-36.1M
Gross Margin
Operating Margin
38.1%
-126.9%
Net Margin
31.3%
-165.4%
Revenue YoY
-1.3%
-25.3%
Net Profit YoY
78.3%
-596.9%
EPS (diluted)
$0.61
$-4.67

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CASS
CASS
NKTR
NKTR
Q4 25
$26.2M
$21.8M
Q3 25
$27.4M
$11.8M
Q2 25
$27.6M
$11.2M
Q1 25
$26.8M
$10.5M
Q4 24
$26.5M
$29.2M
Q3 24
$28.1M
$24.1M
Q2 24
$27.6M
$23.5M
Q1 24
$27.7M
$21.6M
Net Profit
CASS
CASS
NKTR
NKTR
Q4 25
$8.2M
$-36.1M
Q3 25
$9.1M
$-35.5M
Q2 25
$8.9M
$-41.6M
Q1 25
$9.0M
$-50.9M
Q4 24
$4.6M
$7.3M
Q3 24
$2.9M
$-37.1M
Q2 24
$4.5M
$-52.4M
Q1 24
$7.2M
$-36.8M
Gross Margin
CASS
CASS
NKTR
NKTR
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
72.7%
Q3 24
81.6%
Q2 24
58.5%
Q1 24
60.6%
Operating Margin
CASS
CASS
NKTR
NKTR
Q4 25
38.1%
-126.9%
Q3 25
42.3%
-268.6%
Q2 25
22.8%
-324.2%
Q1 25
40.6%
-425.8%
Q4 24
19.7%
49.2%
Q3 24
13.4%
-142.4%
Q2 24
20.2%
-211.9%
Q1 24
32.1%
-163.7%
Net Margin
CASS
CASS
NKTR
NKTR
Q4 25
31.3%
-165.4%
Q3 25
33.2%
-301.3%
Q2 25
32.1%
-372.2%
Q1 25
33.5%
-486.4%
Q4 24
17.3%
24.9%
Q3 24
10.5%
-153.6%
Q2 24
16.2%
-222.9%
Q1 24
25.8%
-170.1%
EPS (diluted)
CASS
CASS
NKTR
NKTR
Q4 25
$0.61
$-4.67
Q3 25
$0.68
$-1.87
Q2 25
$0.66
$-2.95
Q1 25
$0.66
$-0.24
Q4 24
$0.34
$-2.07
Q3 24
$0.21
$-2.66
Q2 24
$0.32
$-3.76
Q1 24
$0.52
$-0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CASS
CASS
NKTR
NKTR
Cash + ST InvestmentsLiquidity on hand
$758.4M
$15.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$243.0M
$89.8M
Total Assets
$2.6B
$280.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CASS
CASS
NKTR
NKTR
Q4 25
$758.4M
$15.1M
Q3 25
$486.6M
$41.0M
Q2 25
$431.2M
$43.0M
Q1 25
$428.9M
$38.9M
Q4 24
$680.1M
$44.3M
Q3 24
$432.0M
$30.1M
Q2 24
$441.7M
$27.9M
Q1 24
$368.3M
$48.6M
Stockholders' Equity
CASS
CASS
NKTR
NKTR
Q4 25
$243.0M
$89.8M
Q3 25
$243.4M
$85.1M
Q2 25
$240.8M
$-24.2M
Q1 25
$234.2M
$13.7M
Q4 24
$229.0M
$60.7M
Q3 24
$237.6M
$48.9M
Q2 24
$229.9M
$79.7M
Q1 24
$229.5M
$126.7M
Total Assets
CASS
CASS
NKTR
NKTR
Q4 25
$2.6B
$280.4M
Q3 25
$2.5B
$301.3M
Q2 25
$2.3B
$207.5M
Q1 25
$2.3B
$256.2M
Q4 24
$2.4B
$303.9M
Q3 24
$2.3B
$308.0M
Q2 24
$2.3B
$343.3M
Q1 24
$2.3B
$396.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CASS
CASS
NKTR
NKTR
Operating Cash FlowLast quarter
$4.8M
$-65.0M
Free Cash FlowOCF − Capex
$4.1M
$-65.0M
FCF MarginFCF / Revenue
15.8%
-298.0%
Capex IntensityCapex / Revenue
2.7%
0.1%
Cash ConversionOCF / Net Profit
0.59×
TTM Free Cash FlowTrailing 4 quarters
$31.8M
$-208.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CASS
CASS
NKTR
NKTR
Q4 25
$4.8M
$-65.0M
Q3 25
$12.3M
$-48.8M
Q2 25
$-1.3M
$-45.7M
Q1 25
$21.6M
$-49.1M
Q4 24
$18.6M
$-46.2M
Q3 24
$-198.0K
$-43.9M
Q2 24
$10.7M
$-37.7M
Q1 24
$9.8M
$-47.9M
Free Cash Flow
CASS
CASS
NKTR
NKTR
Q4 25
$4.1M
$-65.0M
Q3 25
$11.3M
$-48.9M
Q2 25
$-2.6M
$-45.8M
Q1 25
$19.0M
$-49.1M
Q4 24
$18.4M
$-46.6M
Q3 24
$-2.2M
$-44.6M
Q2 24
$7.9M
$-37.9M
Q1 24
$6.3M
$-48.0M
FCF Margin
CASS
CASS
NKTR
NKTR
Q4 25
15.8%
-298.0%
Q3 25
41.1%
-414.5%
Q2 25
-9.5%
-409.6%
Q1 25
71.0%
-469.0%
Q4 24
69.5%
-159.9%
Q3 24
-8.0%
-184.9%
Q2 24
28.6%
-161.3%
Q1 24
22.9%
-222.0%
Capex Intensity
CASS
CASS
NKTR
NKTR
Q4 25
2.7%
0.1%
Q3 25
3.8%
1.0%
Q2 25
4.9%
0.3%
Q1 25
9.6%
0.0%
Q4 24
0.7%
1.6%
Q3 24
7.2%
2.8%
Q2 24
10.1%
0.8%
Q1 24
12.6%
0.7%
Cash Conversion
CASS
CASS
NKTR
NKTR
Q4 25
0.59×
Q3 25
1.35×
Q2 25
-0.15×
Q1 25
2.41×
Q4 24
4.06×
-6.36×
Q3 24
-0.07×
Q2 24
2.38×
Q1 24
1.37×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CASS
CASS

Processing Fees$15.9M61%
Financial Fees$9.9M38%

NKTR
NKTR

Segment breakdown not available.

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