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Side-by-side financial comparison of CASS INFORMATION SYSTEMS INC (CASS) and Intellia Therapeutics, Inc. (NTLA). Click either name above to swap in a different company.

CASS INFORMATION SYSTEMS INC is the larger business by last-quarter revenue ($26.2M vs $23.0M, roughly 1.1× Intellia Therapeutics, Inc.). CASS INFORMATION SYSTEMS INC runs the higher net margin — 31.3% vs -416.2%, a 447.4% gap on every dollar of revenue. On growth, Intellia Therapeutics, Inc. posted the faster year-over-year revenue change (78.8% vs -1.3%). CASS INFORMATION SYSTEMS INC produced more free cash flow last quarter ($4.1M vs $-69.4M). Over the past eight quarters, CASS INFORMATION SYSTEMS INC's revenue compounded faster (-2.8% CAGR vs -10.8%).

Cass Information Systems Inc is a leading provider of integrated financial automation and information management solutions for enterprises. Its core services cover freight payment processing, utility expense management, commercial payment services, and supporting data analytics tools, helping clients streamline financial workflows, cut operational costs, and gain clearer cross-category spending visibility to support smarter business decisions.

Intellia Therapeutics, Inc. is an American clinical-stage biotechnology company focused on developing novel, potentially curative therapeutics leveraging CRISPR-based technologies. The company's in vivo programs use intravenously administered CRISPR as the therapy, in which the company's proprietary delivery technology enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy by using engineere...

CASS vs NTLA — Head-to-Head

Bigger by revenue
CASS
CASS
1.1× larger
CASS
$26.2M
$23.0M
NTLA
Growing faster (revenue YoY)
NTLA
NTLA
+80.1% gap
NTLA
78.8%
-1.3%
CASS
Higher net margin
CASS
CASS
447.4% more per $
CASS
31.3%
-416.2%
NTLA
More free cash flow
CASS
CASS
$73.5M more FCF
CASS
$4.1M
$-69.4M
NTLA
Faster 2-yr revenue CAGR
CASS
CASS
Annualised
CASS
-2.8%
-10.8%
NTLA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CASS
CASS
NTLA
NTLA
Revenue
$26.2M
$23.0M
Net Profit
$8.2M
$-95.8M
Gross Margin
Operating Margin
38.1%
-428.9%
Net Margin
31.3%
-416.2%
Revenue YoY
-1.3%
78.8%
Net Profit YoY
78.3%
25.7%
EPS (diluted)
$0.61
$-0.81

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CASS
CASS
NTLA
NTLA
Q4 25
$26.2M
$23.0M
Q3 25
$27.4M
$13.8M
Q2 25
$27.6M
$14.2M
Q1 25
$26.8M
$16.6M
Q4 24
$26.5M
$12.9M
Q3 24
$28.1M
$9.1M
Q2 24
$27.6M
$7.0M
Q1 24
$27.7M
$28.9M
Net Profit
CASS
CASS
NTLA
NTLA
Q4 25
$8.2M
$-95.8M
Q3 25
$9.1M
$-101.3M
Q2 25
$8.9M
$-101.3M
Q1 25
$9.0M
$-114.3M
Q4 24
$4.6M
$-128.9M
Q3 24
$2.9M
$-135.7M
Q2 24
$4.5M
$-147.0M
Q1 24
$7.2M
$-107.4M
Operating Margin
CASS
CASS
NTLA
NTLA
Q4 25
38.1%
-428.9%
Q3 25
42.3%
-808.9%
Q2 25
22.8%
-772.2%
Q1 25
40.6%
-726.6%
Q4 24
19.7%
-1059.9%
Q3 24
13.4%
-1589.0%
Q2 24
20.2%
-1998.6%
Q1 24
32.1%
-394.0%
Net Margin
CASS
CASS
NTLA
NTLA
Q4 25
31.3%
-416.2%
Q3 25
33.2%
-735.2%
Q2 25
32.1%
-710.8%
Q1 25
33.5%
-687.6%
Q4 24
17.3%
-1001.2%
Q3 24
10.5%
-1489.5%
Q2 24
16.2%
-2112.6%
Q1 24
25.8%
-371.3%
EPS (diluted)
CASS
CASS
NTLA
NTLA
Q4 25
$0.61
$-0.81
Q3 25
$0.68
$-0.92
Q2 25
$0.66
$-0.98
Q1 25
$0.66
$-1.10
Q4 24
$0.34
$-1.27
Q3 24
$0.21
$-1.34
Q2 24
$0.32
$-1.52
Q1 24
$0.52
$-1.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CASS
CASS
NTLA
NTLA
Cash + ST InvestmentsLiquidity on hand
$758.4M
$449.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$243.0M
$671.4M
Total Assets
$2.6B
$842.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CASS
CASS
NTLA
NTLA
Q4 25
$758.4M
$449.9M
Q3 25
$486.6M
$511.0M
Q2 25
$431.2M
$459.7M
Q1 25
$428.9M
$503.7M
Q4 24
$680.1M
$601.5M
Q3 24
$432.0M
$658.1M
Q2 24
$441.7M
$691.1M
Q1 24
$368.3M
$791.3M
Stockholders' Equity
CASS
CASS
NTLA
NTLA
Q4 25
$243.0M
$671.4M
Q3 25
$243.4M
$748.4M
Q2 25
$240.8M
$715.3M
Q1 25
$234.2M
$779.9M
Q4 24
$229.0M
$872.0M
Q3 24
$237.6M
$962.6M
Q2 24
$229.9M
$971.1M
Q1 24
$229.5M
$1.0B
Total Assets
CASS
CASS
NTLA
NTLA
Q4 25
$2.6B
$842.1M
Q3 25
$2.5B
$925.3M
Q2 25
$2.3B
$898.9M
Q1 25
$2.3B
$986.2M
Q4 24
$2.4B
$1.2B
Q3 24
$2.3B
$1.2B
Q2 24
$2.3B
$1.2B
Q1 24
$2.3B
$1.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CASS
CASS
NTLA
NTLA
Operating Cash FlowLast quarter
$4.8M
$-69.3M
Free Cash FlowOCF − Capex
$4.1M
$-69.4M
FCF MarginFCF / Revenue
15.8%
-301.6%
Capex IntensityCapex / Revenue
2.7%
0.5%
Cash ConversionOCF / Net Profit
0.59×
TTM Free Cash FlowTrailing 4 quarters
$31.8M
$-395.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CASS
CASS
NTLA
NTLA
Q4 25
$4.8M
$-69.3M
Q3 25
$12.3M
$-76.9M
Q2 25
$-1.3M
$-99.6M
Q1 25
$21.6M
$-148.9M
Q4 24
$18.6M
$-85.2M
Q3 24
$-198.0K
$-84.8M
Q2 24
$10.7M
$-58.2M
Q1 24
$9.8M
$-120.7M
Free Cash Flow
CASS
CASS
NTLA
NTLA
Q4 25
$4.1M
$-69.4M
Q3 25
$11.3M
$-76.9M
Q2 25
$-2.6M
$-99.9M
Q1 25
$19.0M
$-149.7M
Q4 24
$18.4M
$-86.2M
Q3 24
$-2.2M
$-86.1M
Q2 24
$7.9M
$-59.2M
Q1 24
$6.3M
$-123.2M
FCF Margin
CASS
CASS
NTLA
NTLA
Q4 25
15.8%
-301.6%
Q3 25
41.1%
-558.2%
Q2 25
-9.5%
-701.0%
Q1 25
71.0%
-900.1%
Q4 24
69.5%
-669.4%
Q3 24
-8.0%
-945.2%
Q2 24
28.6%
-850.9%
Q1 24
22.9%
-425.7%
Capex Intensity
CASS
CASS
NTLA
NTLA
Q4 25
2.7%
0.5%
Q3 25
3.8%
0.2%
Q2 25
4.9%
1.7%
Q1 25
9.6%
4.4%
Q4 24
0.7%
7.6%
Q3 24
7.2%
14.0%
Q2 24
10.1%
14.5%
Q1 24
12.6%
8.7%
Cash Conversion
CASS
CASS
NTLA
NTLA
Q4 25
0.59×
Q3 25
1.35×
Q2 25
-0.15×
Q1 25
2.41×
Q4 24
4.06×
Q3 24
-0.07×
Q2 24
2.38×
Q1 24
1.37×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CASS
CASS

Processing Fees$15.9M61%
Financial Fees$9.9M38%

NTLA
NTLA

Avencell Therapeutics Inc$21.0M91%
Other$1.0M4%
Avencell$1.0M4%

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