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Side-by-side financial comparison of Carlyle Group Inc. (CG) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $1.9B, roughly 1.7× Carlyle Group Inc.). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 18.8%, a 18.5% gap on every dollar of revenue. On growth, Carlyle Group Inc. posted the faster year-over-year revenue change (84.1% vs 9.5%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $-1.2B). Over the past eight quarters, Carlyle Group Inc.'s revenue compounded faster (66.2% CAGR vs 8.9%).

The Carlyle Group Inc. is an American multinational company with operations in private equity, alternative asset management and financial services. As of 2023, the company had $426 billion of assets under management.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

CG vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.7× larger
VRTX
$3.2B
$1.9B
CG
Growing faster (revenue YoY)
CG
CG
+74.6% gap
CG
84.1%
9.5%
VRTX
Higher net margin
VRTX
VRTX
18.5% more per $
VRTX
37.3%
18.8%
CG
More free cash flow
VRTX
VRTX
$1.6B more FCF
VRTX
$348.6M
$-1.2B
CG
Faster 2-yr revenue CAGR
CG
CG
Annualised
CG
66.2%
8.9%
VRTX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CG
CG
VRTX
VRTX
Revenue
$1.9B
$3.2B
Net Profit
$358.1M
$1.2B
Gross Margin
85.4%
Operating Margin
24.3%
37.8%
Net Margin
18.8%
37.3%
Revenue YoY
84.1%
9.5%
Net Profit YoY
69.8%
30.5%
EPS (diluted)
$0.96
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CG
CG
VRTX
VRTX
Q4 25
$1.9B
$3.2B
Q3 25
$332.7M
$3.1B
Q2 25
$1.6B
$3.0B
Q1 25
$973.1M
$2.8B
Q4 24
$1.0B
$2.9B
Q3 24
$2.6B
$2.8B
Q2 24
$1.1B
$2.6B
Q1 24
$688.4M
$2.7B
Net Profit
CG
CG
VRTX
VRTX
Q4 25
$358.1M
$1.2B
Q3 25
$900.0K
$1.1B
Q2 25
$319.7M
$1.0B
Q1 25
$130.0M
$646.3M
Q4 24
$210.9M
$913.0M
Q3 24
$595.7M
$1.0B
Q2 24
$148.2M
$-3.6B
Q1 24
$65.6M
$1.1B
Gross Margin
CG
CG
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Q1 24
87.3%
Operating Margin
CG
CG
VRTX
VRTX
Q4 25
24.3%
37.8%
Q3 25
25.8%
38.6%
Q2 25
28.0%
38.8%
Q1 25
17.6%
22.7%
Q4 24
25.7%
35.2%
Q3 24
29.9%
40.3%
Q2 24
20.5%
-132.9%
Q1 24
17.5%
42.4%
Net Margin
CG
CG
VRTX
VRTX
Q4 25
18.8%
37.3%
Q3 25
0.3%
35.2%
Q2 25
20.3%
34.8%
Q1 25
13.4%
23.3%
Q4 24
20.4%
31.4%
Q3 24
22.6%
37.7%
Q2 24
13.9%
-135.8%
Q1 24
9.5%
40.9%
EPS (diluted)
CG
CG
VRTX
VRTX
Q4 25
$0.96
$4.64
Q3 25
$0.00
$4.20
Q2 25
$0.87
$3.99
Q1 25
$0.35
$2.49
Q4 24
$0.56
$3.62
Q3 24
$1.63
$4.01
Q2 24
$0.40
$-13.92
Q1 24
$0.18
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CG
CG
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$2.0B
$6.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$7.1B
$18.7B
Total Assets
$29.1B
$25.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CG
CG
VRTX
VRTX
Q4 25
$2.0B
$6.6B
Q3 25
$2.2B
$6.3B
Q2 25
$1.3B
$6.4B
Q1 25
$1.2B
$6.2B
Q4 24
$1.3B
$6.1B
Q3 24
$1.4B
$6.5B
Q2 24
$914.8M
$5.8B
Q1 24
$1.3B
$10.2B
Stockholders' Equity
CG
CG
VRTX
VRTX
Q4 25
$7.1B
$18.7B
Q3 25
$6.8B
$17.3B
Q2 25
$6.7B
$17.2B
Q1 25
$6.4B
$16.5B
Q4 24
$6.3B
$16.4B
Q3 24
$6.3B
$15.6B
Q2 24
$5.7B
$14.8B
Q1 24
$5.7B
$18.5B
Total Assets
CG
CG
VRTX
VRTX
Q4 25
$29.1B
$25.6B
Q3 25
$27.1B
$24.9B
Q2 25
$25.1B
$24.0B
Q1 25
$24.1B
$22.9B
Q4 24
$23.1B
$22.5B
Q3 24
$22.7B
$22.2B
Q2 24
$22.3B
$20.1B
Q1 24
$20.8B
$23.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CG
CG
VRTX
VRTX
Operating Cash FlowLast quarter
$-1.2B
$498.0M
Free Cash FlowOCF − Capex
$-1.2B
$348.6M
FCF MarginFCF / Revenue
-65.1%
10.9%
Capex IntensityCapex / Revenue
2.2%
4.7%
Cash ConversionOCF / Net Profit
-3.34×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$-3.4B
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CG
CG
VRTX
VRTX
Q4 25
$-1.2B
$498.0M
Q3 25
$-1.6B
$1.2B
Q2 25
$-168.8M
$1.1B
Q1 25
$-352.1M
$818.9M
Q4 24
$-352.8M
$584.6M
Q3 24
$791.9M
$1.4B
Q2 24
$-1.3B
$-3.8B
Q1 24
$71.1M
$1.3B
Free Cash Flow
CG
CG
VRTX
VRTX
Q4 25
$-1.2B
$348.6M
Q3 25
$-1.6B
$1.1B
Q2 25
$-186.3M
$927.4M
Q1 25
$-368.8M
$778.2M
Q4 24
$-379.5M
$492.0M
Q3 24
$772.8M
$1.3B
Q2 24
$-1.3B
$-3.8B
Q1 24
$56.9M
$1.2B
FCF Margin
CG
CG
VRTX
VRTX
Q4 25
-65.1%
10.9%
Q3 25
-475.7%
37.0%
Q2 25
-11.8%
31.3%
Q1 25
-37.9%
28.1%
Q4 24
-36.8%
16.9%
Q3 24
29.3%
47.0%
Q2 24
-120.4%
-144.5%
Q1 24
8.3%
46.0%
Capex Intensity
CG
CG
VRTX
VRTX
Q4 25
2.2%
4.7%
Q3 25
7.0%
3.3%
Q2 25
1.1%
4.9%
Q1 25
1.7%
1.5%
Q4 24
2.6%
3.2%
Q3 24
0.7%
2.4%
Q2 24
1.7%
2.6%
Q1 24
2.1%
2.5%
Cash Conversion
CG
CG
VRTX
VRTX
Q4 25
-3.34×
0.42×
Q3 25
-1732.78×
1.15×
Q2 25
-0.53×
1.04×
Q1 25
-2.71×
1.27×
Q4 24
-1.67×
0.64×
Q3 24
1.33×
1.31×
Q2 24
-8.57×
Q1 24
1.08×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CG
CG

Fund Management Fee$606.8M32%
Other$528.7M28%
Global Private Equity Segment$307.3M16%
Global Credit Segment$238.0M13%
Carlyle Alp Invest Segment$124.6M7%
Incentive Fee$55.4M3%
Fee Related Performance Revenues$29.2M2%
Investment Advice$11.1M1%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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