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Side-by-side financial comparison of CANADIAN IMPERIAL BANK OF COMMERCE (CM) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

CANADIAN IMPERIAL BANK OF COMMERCE is the larger business by last-quarter revenue ($6.1B vs $3.2B, roughly 1.9× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 36.9%, a 0.4% gap on every dollar of revenue.

The Imperial Bank of Canada was a Canadian bank that operated from 1873 to 1961. In 1961, Imperial merged with the Canadian Bank of Commerce to become the Canadian Imperial Bank of Commerce.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

CM vs VRTX — Head-to-Head

Bigger by revenue
CM
CM
1.9× larger
CM
$6.1B
$3.2B
VRTX
Higher net margin
VRTX
VRTX
0.4% more per $
VRTX
37.3%
36.9%
CM

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
CM
CM
VRTX
VRTX
Revenue
$6.1B
$3.2B
Net Profit
$2.3B
$1.2B
Gross Margin
85.4%
Operating Margin
37.8%
Net Margin
36.9%
37.3%
Revenue YoY
9.5%
Net Profit YoY
30.5%
EPS (diluted)
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CM
CM
VRTX
VRTX
Q1 26
$6.1B
Q4 25
$3.2B
Q3 25
$5.3B
$3.1B
Q2 25
$5.1B
$3.0B
Q1 25
$2.8B
Q4 24
$2.9B
Q3 24
$2.8B
Q2 24
$2.6B
Net Profit
CM
CM
VRTX
VRTX
Q1 26
$2.3B
Q4 25
$1.2B
Q3 25
$1.5B
$1.1B
Q2 25
$1.5B
$1.0B
Q1 25
$646.3M
Q4 24
$913.0M
Q3 24
$1.0B
Q2 24
$-3.6B
Gross Margin
CM
CM
VRTX
VRTX
Q1 26
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
CM
CM
VRTX
VRTX
Q1 26
Q4 25
37.8%
Q3 25
38.6%
Q2 25
38.8%
Q1 25
22.7%
Q4 24
35.2%
Q3 24
40.3%
Q2 24
-132.9%
Net Margin
CM
CM
VRTX
VRTX
Q1 26
36.9%
Q4 25
37.3%
Q3 25
28.9%
35.2%
Q2 25
28.6%
34.8%
Q1 25
23.3%
Q4 24
31.4%
Q3 24
37.7%
Q2 24
-135.8%
EPS (diluted)
CM
CM
VRTX
VRTX
Q1 26
Q4 25
$4.64
Q3 25
$4.20
Q2 25
$3.99
Q1 25
$2.49
Q4 24
$3.62
Q3 24
$4.01
Q2 24
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CM
CM
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$8.0B
$6.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$47.9B
$18.7B
Total Assets
$826.8B
$25.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CM
CM
VRTX
VRTX
Q1 26
$8.0B
Q4 25
$6.6B
Q3 25
$13.9B
$6.3B
Q2 25
$10.2B
$6.4B
Q1 25
$6.2B
Q4 24
$6.1B
Q3 24
$6.5B
Q2 24
$5.8B
Stockholders' Equity
CM
CM
VRTX
VRTX
Q1 26
$47.9B
Q4 25
$18.7B
Q3 25
$45.9B
$17.3B
Q2 25
$45.2B
$17.2B
Q1 25
$16.5B
Q4 24
$16.4B
Q3 24
$15.6B
Q2 24
$14.8B
Total Assets
CM
CM
VRTX
VRTX
Q1 26
$826.8B
Q4 25
$25.6B
Q3 25
$804.6B
$24.9B
Q2 25
$795.8B
$24.0B
Q1 25
$22.9B
Q4 24
$22.5B
Q3 24
$22.2B
Q2 24
$20.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CM
CM
VRTX
VRTX
Operating Cash FlowLast quarter
$-1.6B
$498.0M
Free Cash FlowOCF − Capex
$348.6M
FCF MarginFCF / Revenue
10.9%
Capex IntensityCapex / Revenue
4.7%
Cash ConversionOCF / Net Profit
-0.69×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CM
CM
VRTX
VRTX
Q1 26
$-1.6B
Q4 25
$498.0M
Q3 25
$4.3B
$1.2B
Q2 25
$667.2M
$1.1B
Q1 25
$818.9M
Q4 24
$584.6M
Q3 24
$1.4B
Q2 24
$-3.8B
Free Cash Flow
CM
CM
VRTX
VRTX
Q1 26
Q4 25
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$778.2M
Q4 24
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
FCF Margin
CM
CM
VRTX
VRTX
Q1 26
Q4 25
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
28.1%
Q4 24
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Capex Intensity
CM
CM
VRTX
VRTX
Q1 26
Q4 25
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
1.5%
Q4 24
3.2%
Q3 24
2.4%
Q2 24
2.6%
Cash Conversion
CM
CM
VRTX
VRTX
Q1 26
-0.69×
Q4 25
0.42×
Q3 25
2.80×
1.15×
Q2 25
0.46×
1.04×
Q1 25
1.27×
Q4 24
0.64×
Q3 24
1.31×
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CM
CM

Segment breakdown not available.

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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