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Side-by-side financial comparison of Compass Therapeutics, Inc. (CMPX) and PALVELLA THERAPEUTICS, INC. (PVLA). Click either name above to swap in a different company.

Compass Pathways, or COMPASS Pathways, is a British pharmaceutical company developing psychedelics as potential medicines. Its main drug candidate, psilocybin (COMP360), is currently in phase 3 clinical trials for treatment-resistant depression. This candidate has received breakthrough therapy status from the U.S. Food and Drug Administration (FDA). It is the most advanced psychedelic drug candidate in development besides Lykos Therapeutics's midomafetamine (MDMA).

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing targeted therapies for rare, debilitating genetic diseases with high unmet medical needs. Its lead product candidates address congenital disorders, serving global patient populations that lack effective existing treatment options.

CMPX vs PVLA — Head-to-Head

Bigger by revenue
PVLA
PVLA
Infinity× larger
PVLA
$520.0K
$0
CMPX

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
CMPX
CMPX
PVLA
PVLA
Revenue
$0
$520.0K
Net Profit
$-14.3M
Gross Margin
Operating Margin
Net Margin
Revenue YoY
14.3%
Net Profit YoY
-36.0%
-221.8%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CMPX
CMPX
PVLA
PVLA
Q4 25
$520.0K
Q3 25
$0
$628.0K
Q2 25
$0
$690.0K
Q1 25
$752.0K
Q3 24
$0
$0
Q2 24
$850.0K
$0
Q1 24
$53.0K
Q4 23
$1.3M
Net Profit
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
$-14.3M
$-11.3M
Q2 25
$-19.9M
$-9.5M
Q1 25
$-8.2M
Q3 24
$-10.5M
$-6.8M
Q2 24
$-13.1M
$-4.2M
Q1 24
$-2.5M
Q4 23
Operating Margin
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
-1620.5%
Q2 25
-1340.6%
Q1 25
-1046.7%
Q3 24
Q2 24
-1770.0%
Q1 24
-3318.9%
Q4 23
Net Margin
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
-1806.5%
Q2 25
-1372.6%
Q1 25
-1088.4%
Q3 24
Q2 24
-1538.4%
Q1 24
-4784.9%
Q4 23
EPS (diluted)
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
$-1.03
Q2 25
$-0.86
Q1 25
$-0.74
Q3 24
$-3.94
Q2 24
$-2.47
Q1 24
$-1.54
Q4 23

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CMPX
CMPX
PVLA
PVLA
Cash + ST InvestmentsLiquidity on hand
$219.9M
$58.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$209.6M
$28.0M
Total Assets
$231.3M
$59.6M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CMPX
CMPX
PVLA
PVLA
Q4 25
$58.0M
Q3 25
$219.9M
$63.6M
Q2 25
$100.9M
$70.4M
Q1 25
$75.6M
Q3 24
$118.0M
$19.4M
Q2 24
$146.2M
$19.7M
Q1 24
$19.1M
Q4 23
$16.3M
Stockholders' Equity
CMPX
CMPX
PVLA
PVLA
Q4 25
$28.0M
Q3 25
$209.6M
$38.7M
Q2 25
$93.2M
$47.8M
Q1 25
$55.6M
Q3 24
$138.4M
$-87.4M
Q2 24
$146.1M
$-80.8M
Q1 24
$-76.9M
Q4 23
$-74.5M
Total Assets
CMPX
CMPX
PVLA
PVLA
Q4 25
$59.6M
Q3 25
$231.3M
$66.9M
Q2 25
$116.7M
$73.7M
Q1 25
$79.4M
Q3 24
$149.2M
$20.5M
Q2 24
$155.6M
$25.1M
Q1 24
$29.5M
Q4 23
$7.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CMPX
CMPX
PVLA
PVLA
Operating Cash FlowLast quarter
$-10.8M
$-25.0M
Free Cash FlowOCF − Capex
$-10.9M
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CMPX
CMPX
PVLA
PVLA
Q4 25
$-25.0M
Q3 25
$-10.8M
$-7.9M
Q2 25
$-11.8M
$-5.4M
Q1 25
$-6.8M
Q3 24
$-11.1M
$-2.7M
Q2 24
$-10.8M
$-1.6M
Q1 24
$-1.1M
Q4 23
$-13.7M
Free Cash Flow
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
$-10.9M
Q2 25
Q1 25
Q3 24
$-11.1M
Q2 24
Q1 24
Q4 23
$-13.9M
FCF Margin
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
Q2 25
Q1 25
Q3 24
Q2 24
Q1 24
Q4 23
-1068.1%
Capex Intensity
CMPX
CMPX
PVLA
PVLA
Q4 25
Q3 25
Q2 25
Q1 25
Q3 24
Q2 24
0.0%
Q1 24
0.0%
Q4 23
13.2%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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