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Side-by-side financial comparison of Commerce.com, Inc. (CMRC) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $89.5M, roughly 1.7× Commerce.com, Inc.). Commerce.com, Inc. runs the higher net margin — -9.3% vs -21.1%, a 11.7% gap on every dollar of revenue. On growth, Commerce.com, Inc. posted the faster year-over-year revenue change (2.9% vs -19.2%). Commerce.com, Inc. produced more free cash flow last quarter ($-2.2M vs $-28.6M). Over the past eight quarters, Commerce.com, Inc.'s revenue compounded faster (5.5% CAGR vs -7.5%).

SPS Commerce, Inc. is a technology and application software company based in the United States that provides cloud-based supply chain management software. The company's headquarters are located in Minneapolis, Minnesota, but it also has a US office in New Jersey, and international locations in Amsterdam, Beijing, Breukelen, Hong Kong, Kyiv, Melbourne, Montpellier, Sydney, and Toronto.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

CMRC vs OPK — Head-to-Head

Bigger by revenue
OPK
OPK
1.7× larger
OPK
$148.5M
$89.5M
CMRC
Growing faster (revenue YoY)
CMRC
CMRC
+22.0% gap
CMRC
2.9%
-19.2%
OPK
Higher net margin
CMRC
CMRC
11.7% more per $
CMRC
-9.3%
-21.1%
OPK
More free cash flow
CMRC
CMRC
$26.4M more FCF
CMRC
$-2.2M
$-28.6M
OPK
Faster 2-yr revenue CAGR
CMRC
CMRC
Annualised
CMRC
5.5%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CMRC
CMRC
OPK
OPK
Revenue
$89.5M
$148.5M
Net Profit
$-8.4M
$-31.3M
Gross Margin
78.3%
43.1%
Operating Margin
-7.4%
-25.8%
Net Margin
-9.3%
-21.1%
Revenue YoY
2.9%
-19.2%
Net Profit YoY
-250.0%
-322.8%
EPS (diluted)
$-0.11
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CMRC
CMRC
OPK
OPK
Q4 25
$89.5M
$148.5M
Q3 25
$86.0M
$151.7M
Q2 25
$84.4M
$156.8M
Q1 25
$82.4M
$150.0M
Q4 24
$87.0M
$183.6M
Q3 24
$83.7M
$173.6M
Q2 24
$81.8M
$182.2M
Q1 24
$80.4M
$173.7M
Net Profit
CMRC
CMRC
OPK
OPK
Q4 25
$-8.4M
$-31.3M
Q3 25
$-2.2M
$21.6M
Q2 25
$-8.4M
$-148.4M
Q1 25
$-353.0K
$-67.6M
Q4 24
$-2.4M
$14.0M
Q3 24
$-7.0M
$24.9M
Q2 24
$-11.3M
$-10.3M
Q1 24
$-6.4M
$-81.8M
Gross Margin
CMRC
CMRC
OPK
OPK
Q4 25
78.3%
43.1%
Q3 25
78.4%
32.9%
Q2 25
79.0%
31.5%
Q1 25
79.4%
28.4%
Q4 24
77.6%
46.1%
Q3 24
76.3%
23.1%
Q2 24
75.8%
28.4%
Q1 24
77.1%
24.2%
Operating Margin
CMRC
CMRC
OPK
OPK
Q4 25
-7.4%
-25.8%
Q3 25
-0.5%
31.7%
Q2 25
-8.0%
-38.3%
Q1 25
-2.9%
-44.8%
Q4 24
-0.9%
-18.0%
Q3 24
-23.0%
8.2%
Q2 24
-16.5%
-33.9%
Q1 24
-10.2%
-41.2%
Net Margin
CMRC
CMRC
OPK
OPK
Q4 25
-9.3%
-21.1%
Q3 25
-2.6%
14.3%
Q2 25
-9.9%
-94.7%
Q1 25
-0.4%
-45.1%
Q4 24
-2.7%
7.6%
Q3 24
-8.4%
14.3%
Q2 24
-13.8%
-5.7%
Q1 24
-8.0%
-47.1%
EPS (diluted)
CMRC
CMRC
OPK
OPK
Q4 25
$-0.11
$-0.04
Q3 25
$-0.03
$0.03
Q2 25
$-0.10
$-0.19
Q1 25
$0.00
$-0.10
Q4 24
$-0.03
$0.02
Q3 24
$-0.09
$0.03
Q2 24
$-0.15
$-0.01
Q1 24
$-0.08
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CMRC
CMRC
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$141.1M
$364.4M
Total DebtLower is stronger
$157.0M
$344.0M
Stockholders' EquityBook value
$39.4M
$1.3B
Total Assets
$308.8M
$1.9B
Debt / EquityLower = less leverage
3.99×
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CMRC
CMRC
OPK
OPK
Q4 25
$141.1M
$364.4M
Q3 25
$142.0M
$412.0M
Q2 25
$134.5M
$267.3M
Q1 25
$120.7M
$428.8M
Q4 24
$178.2M
$426.6M
Q3 24
$168.4M
$400.1M
Q2 24
$275.8M
$40.6M
Q1 24
$265.2M
$75.6M
Total Debt
CMRC
CMRC
OPK
OPK
Q4 25
$157.0M
$344.0M
Q3 25
$157.3M
$344.2M
Q2 25
$157.5M
$343.3M
Q1 25
$157.8M
$439.2M
Q4 24
$216.5M
$437.2M
Q3 24
$441.0M
Q2 24
$340.9M
$201.9M
Q1 24
$340.5M
$350.1M
Stockholders' Equity
CMRC
CMRC
OPK
OPK
Q4 25
$39.4M
$1.3B
Q3 25
$42.8M
$1.3B
Q2 25
$38.8M
$1.3B
Q1 25
$38.1M
$1.3B
Q4 24
$33.4M
$1.4B
Q3 24
$29.0M
$1.4B
Q2 24
$26.1M
$1.4B
Q1 24
$26.9M
$1.3B
Total Assets
CMRC
CMRC
OPK
OPK
Q4 25
$308.8M
$1.9B
Q3 25
$309.5M
$2.0B
Q2 25
$302.5M
$2.0B
Q1 25
$286.3M
$2.1B
Q4 24
$340.3M
$2.2B
Q3 24
$335.1M
$2.3B
Q2 24
$452.5M
$2.0B
Q1 24
$442.5M
$2.0B
Debt / Equity
CMRC
CMRC
OPK
OPK
Q4 25
3.99×
0.27×
Q3 25
3.67×
0.26×
Q2 25
4.06×
0.26×
Q1 25
4.14×
0.33×
Q4 24
6.49×
0.32×
Q3 24
0.31×
Q2 24
13.06×
0.14×
Q1 24
12.65×
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CMRC
CMRC
OPK
OPK
Operating Cash FlowLast quarter
$980.0K
$-25.9M
Free Cash FlowOCF − Capex
$-2.2M
$-28.6M
FCF MarginFCF / Revenue
-2.4%
-19.3%
Capex IntensityCapex / Revenue
3.5%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$16.9M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CMRC
CMRC
OPK
OPK
Q4 25
$980.0K
$-25.9M
Q3 25
$10.6M
$-34.6M
Q2 25
$13.6M
$-83.4M
Q1 25
$401.0K
$-34.6M
Q4 24
$12.4M
$-44.4M
Q3 24
$5.6M
$-77.1M
Q2 24
$11.7M
$-26.4M
Q1 24
$-3.4M
$-35.6M
Free Cash Flow
CMRC
CMRC
OPK
OPK
Q4 25
$-2.2M
$-28.6M
Q3 25
$7.6M
$-37.8M
Q2 25
$11.9M
$-86.7M
Q1 25
$-424.0K
$-37.7M
Q4 24
$11.6M
$-49.8M
Q3 24
$4.5M
$-85.0M
Q2 24
$10.7M
$-33.7M
Q1 24
$-4.2M
$-40.0M
FCF Margin
CMRC
CMRC
OPK
OPK
Q4 25
-2.4%
-19.3%
Q3 25
8.8%
-24.9%
Q2 25
14.1%
-55.3%
Q1 25
-0.5%
-25.2%
Q4 24
13.3%
-27.1%
Q3 24
5.4%
-49.0%
Q2 24
13.0%
-18.5%
Q1 24
-5.3%
-23.0%
Capex Intensity
CMRC
CMRC
OPK
OPK
Q4 25
3.5%
1.8%
Q3 25
3.4%
2.1%
Q2 25
2.0%
2.1%
Q1 25
1.0%
2.1%
Q4 24
0.9%
2.9%
Q3 24
1.3%
4.6%
Q2 24
1.3%
4.0%
Q1 24
1.0%
2.6%
Cash Conversion
CMRC
CMRC
OPK
OPK
Q4 25
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CMRC
CMRC

Subscription And Circulation$65.2M73%
Partner And Services$24.4M27%

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

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