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Side-by-side financial comparison of COLLEGIUM PHARMACEUTICAL, INC (COLL) and Pacira BioSciences, Inc. (PCRX). Click either name above to swap in a different company.

COLLEGIUM PHARMACEUTICAL, INC is the larger business by last-quarter revenue ($205.4M vs $196.9M, roughly 1.0× Pacira BioSciences, Inc.). On growth, COLLEGIUM PHARMACEUTICAL, INC posted the faster year-over-year revenue change (12.9% vs 5.1%). COLLEGIUM PHARMACEUTICAL, INC produced more free cash flow last quarter ($122.4M vs $43.5M). Over the past eight quarters, COLLEGIUM PHARMACEUTICAL, INC's revenue compounded faster (19.1% CAGR vs 8.5%).

Collegium Pharmaceutical, Inc. is a specialty pharmaceutical firm focused on developing and commercializing innovative, abuse-deterrent pain management therapies. Operating primarily in the U.S. market, it offers extended-release analgesics for chronic pain patients, serving providers across primary and specialty care segments.

Pacira BioSciences, Inc. is a specialty pharmaceutical company focused on developing and commercializing non-opioid pain management solutions. Its core product line targets post-surgical pain relief for patients, serving hospitals, ambulatory surgery centers and other healthcare providers primarily in the U.S., with ongoing expansion efforts in select international markets.

COLL vs PCRX — Head-to-Head

Bigger by revenue
COLL
COLL
1.0× larger
COLL
$205.4M
$196.9M
PCRX
Growing faster (revenue YoY)
COLL
COLL
+7.8% gap
COLL
12.9%
5.1%
PCRX
More free cash flow
COLL
COLL
$78.9M more FCF
COLL
$122.4M
$43.5M
PCRX
Faster 2-yr revenue CAGR
COLL
COLL
Annualised
COLL
19.1%
8.5%
PCRX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
COLL
COLL
PCRX
PCRX
Revenue
$205.4M
$196.9M
Net Profit
$17.0M
Gross Margin
62.5%
79.5%
Operating Margin
29.6%
1.2%
Net Margin
8.3%
Revenue YoY
12.9%
5.1%
Net Profit YoY
35.3%
EPS (diluted)
$0.48
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
COLL
COLL
PCRX
PCRX
Q4 25
$205.4M
$196.9M
Q3 25
$209.4M
$179.5M
Q2 25
$188.0M
$181.1M
Q1 25
$177.8M
$168.9M
Q4 24
$181.9M
$187.3M
Q3 24
$159.3M
$168.6M
Q2 24
$145.3M
$178.0M
Q1 24
$144.9M
$167.1M
Net Profit
COLL
COLL
PCRX
PCRX
Q4 25
$17.0M
Q3 25
$31.5M
$5.4M
Q2 25
$12.0M
$-4.8M
Q1 25
$2.4M
$4.8M
Q4 24
$12.5M
Q3 24
$9.3M
$-143.5M
Q2 24
$19.6M
$18.9M
Q1 24
$27.7M
$9.0M
Gross Margin
COLL
COLL
PCRX
PCRX
Q4 25
62.5%
79.5%
Q3 25
61.7%
80.9%
Q2 25
57.7%
77.4%
Q1 25
54.8%
79.7%
Q4 24
54.0%
78.7%
Q3 24
60.8%
76.9%
Q2 24
62.5%
75.1%
Q1 24
63.1%
71.6%
Operating Margin
COLL
COLL
PCRX
PCRX
Q4 25
29.6%
1.2%
Q3 25
29.7%
3.5%
Q2 25
18.7%
4.7%
Q1 25
12.2%
1.2%
Q4 24
20.9%
13.2%
Q3 24
21.9%
-82.8%
Q2 24
32.7%
15.9%
Q1 24
34.1%
7.9%
Net Margin
COLL
COLL
PCRX
PCRX
Q4 25
8.3%
Q3 25
15.0%
3.0%
Q2 25
6.4%
-2.7%
Q1 25
1.4%
2.8%
Q4 24
6.9%
Q3 24
5.9%
-85.1%
Q2 24
13.5%
10.6%
Q1 24
19.1%
5.4%
EPS (diluted)
COLL
COLL
PCRX
PCRX
Q4 25
$0.48
$0.05
Q3 25
$0.84
$0.12
Q2 25
$0.34
$-0.11
Q1 25
$0.07
$0.10
Q4 24
$0.36
$0.38
Q3 24
$0.27
$-3.11
Q2 24
$0.52
$0.39
Q1 24
$0.71
$0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
COLL
COLL
PCRX
PCRX
Cash + ST InvestmentsLiquidity on hand
$386.7M
$238.4M
Total DebtLower is stronger
$372.2M
Stockholders' EquityBook value
$301.7M
$693.1M
Total Assets
$1.7B
$1.3B
Debt / EquityLower = less leverage
0.54×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
COLL
COLL
PCRX
PCRX
Q4 25
$386.7M
$238.4M
Q3 25
$285.9M
$246.3M
Q2 25
$222.2M
$445.9M
Q1 25
$197.8M
$493.6M
Q4 24
$162.8M
$484.6M
Q3 24
$120.0M
$453.8M
Q2 24
$271.6M
$404.2M
Q1 24
$318.0M
$325.9M
Total Debt
COLL
COLL
PCRX
PCRX
Q4 25
$372.2M
Q3 25
$376.7M
Q2 25
$580.5M
Q1 25
$583.4M
Q4 24
$585.3M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
COLL
COLL
PCRX
PCRX
Q4 25
$301.7M
$693.1M
Q3 25
$274.8M
$727.2M
Q2 25
$232.2M
$757.8M
Q1 25
$234.4M
$798.5M
Q4 24
$228.8M
$778.3M
Q3 24
$234.3M
$749.6M
Q2 24
$216.6M
$879.3M
Q1 24
$222.2M
$892.2M
Total Assets
COLL
COLL
PCRX
PCRX
Q4 25
$1.7B
$1.3B
Q3 25
$1.6B
$1.3B
Q2 25
$1.6B
$1.5B
Q1 25
$1.6B
$1.6B
Q4 24
$1.7B
$1.6B
Q3 24
$1.6B
$1.5B
Q2 24
$1.1B
$1.6B
Q1 24
$1.1B
$1.6B
Debt / Equity
COLL
COLL
PCRX
PCRX
Q4 25
0.54×
Q3 25
0.52×
Q2 25
0.77×
Q1 25
0.73×
Q4 24
0.75×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
COLL
COLL
PCRX
PCRX
Operating Cash FlowLast quarter
$123.0M
$43.7M
Free Cash FlowOCF − Capex
$122.4M
$43.5M
FCF MarginFCF / Revenue
59.6%
22.1%
Capex IntensityCapex / Revenue
0.3%
0.1%
Cash ConversionOCF / Net Profit
7.25×
TTM Free Cash FlowTrailing 4 quarters
$327.6M
$136.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
COLL
COLL
PCRX
PCRX
Q4 25
$123.0M
$43.7M
Q3 25
$78.4M
$60.8M
Q2 25
$72.4M
$12.0M
Q1 25
$55.4M
$35.5M
Q4 24
$84.6M
$33.1M
Q3 24
$-9.0M
$53.9M
Q2 24
$67.4M
$53.2M
Q1 24
$61.9M
$49.1M
Free Cash Flow
COLL
COLL
PCRX
PCRX
Q4 25
$122.4M
$43.5M
Q3 25
$78.3M
$57.0M
Q2 25
$72.4M
$9.3M
Q1 25
$54.6M
$26.9M
Q4 24
$84.1M
$31.0M
Q3 24
$-9.2M
$49.8M
Q2 24
$67.1M
$51.6M
Q1 24
$61.4M
$46.3M
FCF Margin
COLL
COLL
PCRX
PCRX
Q4 25
59.6%
22.1%
Q3 25
37.4%
31.7%
Q2 25
38.5%
5.1%
Q1 25
30.7%
15.9%
Q4 24
46.2%
16.6%
Q3 24
-5.8%
29.6%
Q2 24
46.2%
29.0%
Q1 24
42.3%
27.7%
Capex Intensity
COLL
COLL
PCRX
PCRX
Q4 25
0.3%
0.1%
Q3 25
0.1%
2.2%
Q2 25
0.0%
1.5%
Q1 25
0.4%
5.1%
Q4 24
0.3%
1.1%
Q3 24
0.2%
2.4%
Q2 24
0.2%
0.9%
Q1 24
0.4%
1.7%
Cash Conversion
COLL
COLL
PCRX
PCRX
Q4 25
7.25×
Q3 25
2.49×
11.20×
Q2 25
6.05×
Q1 25
22.92×
7.37×
Q4 24
6.75×
Q3 24
-0.96×
Q2 24
3.44×
2.82×
Q1 24
2.23×
5.47×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

COLL
COLL

Segment breakdown not available.

PCRX
PCRX

EXPAREL$155.8M79%
ZILRETTA$33.0M17%
Iovera$7.0M4%

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