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Side-by-side financial comparison of Caribou Biosciences, Inc. (CRBU) and Heritage Distilling Holding Company, Inc. (IPST). Click either name above to swap in a different company.

Heritage Distilling Holding Company, Inc. is the larger business by last-quarter revenue ($4.7M vs $3.9M, roughly 1.2× Caribou Biosciences, Inc.). Caribou Biosciences, Inc. runs the higher net margin — -672.1% vs -6862.0%, a 6189.9% gap on every dollar of revenue.

Caribou Biosciences, Inc. is a clinical-stage biotechnology company focused on developing CRISPR genome-edited cell therapies for cancers and autoimmune diseases. It operates mainly in North American and European markets, partnering with leading pharmaceutical enterprises to advance its pipeline of accessible, targeted therapeutic products for global patients.

Newport Craft Brewing & Distilling Company is a brewery and distillery located in Newport, Rhode Island. Established in 1999 as the Coastal Extreme Brewing Company, it was the first microbrewery in Newport and began distilling operations in 2006. The company produces a range of beers and spirits that are distributed in the Northeastern United States. In 2018 it adopted its current name to reflect its combined brewing and distilling operations. Newport Craft is owned by Audrain Hospitality Gro...

CRBU vs IPST — Head-to-Head

Bigger by revenue
IPST
IPST
1.2× larger
IPST
$4.7M
$3.9M
CRBU
Higher net margin
CRBU
CRBU
6189.9% more per $
CRBU
-672.1%
-6862.0%
IPST

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CRBU
CRBU
IPST
IPST
Revenue
$3.9M
$4.7M
Net Profit
$-26.5M
$-323.7M
Gross Margin
68.5%
Operating Margin
-722.0%
-2622.6%
Net Margin
-672.1%
-6862.0%
Revenue YoY
89.7%
Net Profit YoY
25.4%
EPS (diluted)
$-0.28
$-31.89

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRBU
CRBU
IPST
IPST
Q4 25
$3.9M
$4.7M
Q3 25
$2.2M
$3.0M
Q2 25
$2.7M
$1.3M
Q1 25
$2.4M
$1.1M
Q4 24
$2.1M
Q3 24
$2.0M
$1.8M
Q2 24
$3.5M
Q1 24
$2.4M
Net Profit
CRBU
CRBU
IPST
IPST
Q4 25
$-26.5M
$-323.7M
Q3 25
$-27.5M
$196.3M
Q2 25
$-54.1M
$-7.3M
Q1 25
$-40.0M
$-3.0M
Q4 24
Q3 24
$-34.7M
$-3.4M
Q2 24
$-37.7M
Q1 24
$-41.2M
Gross Margin
CRBU
CRBU
IPST
IPST
Q4 25
68.5%
Q3 25
61.3%
Q2 25
17.2%
Q1 25
24.9%
Q4 24
Q3 24
35.8%
Q2 24
Q1 24
Operating Margin
CRBU
CRBU
IPST
IPST
Q4 25
-722.0%
-2622.6%
Q3 25
-1337.6%
-38.4%
Q2 25
-1784.0%
-503.0%
Q1 25
-1823.8%
-224.5%
Q4 24
Q3 24
-1889.2%
-118.1%
Q2 24
-1255.8%
Q1 24
-1893.9%
Net Margin
CRBU
CRBU
IPST
IPST
Q4 25
-672.1%
-6862.0%
Q3 25
-1253.3%
6566.2%
Q2 25
-2028.4%
-551.9%
Q1 25
-1699.6%
-277.8%
Q4 24
Q3 24
-1713.6%
-194.9%
Q2 24
-1088.3%
Q1 24
-1697.6%
EPS (diluted)
CRBU
CRBU
IPST
IPST
Q4 25
$-0.28
$-31.89
Q3 25
$-0.30
$16.97
Q2 25
$-0.58
$-0.77
Q1 25
$-0.43
$-0.34
Q4 24
Q3 24
$-0.38
$-160.41
Q2 24
$-0.42
Q1 24
$-0.46

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRBU
CRBU
IPST
IPST
Cash + ST InvestmentsLiquidity on hand
$12.4M
Total DebtLower is stronger
$2.6M
Stockholders' EquityBook value
$122.2M
$98.2M
Total Assets
$175.4M
$108.8M
Debt / EquityLower = less leverage
0.03×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRBU
CRBU
IPST
IPST
Q4 25
$12.4M
Q3 25
$11.1M
Q2 25
$25.2M
Q1 25
$29.4M
Q4 24
$16.3M
Q3 24
$32.0M
Q2 24
$37.9M
Q1 24
$49.4M
Total Debt
CRBU
CRBU
IPST
IPST
Q4 25
$2.6M
Q3 25
$2.6M
Q2 25
$13.0M
Q1 25
$13.0M
Q4 24
Q3 24
$15.0M
Q2 24
Q1 24
Stockholders' Equity
CRBU
CRBU
IPST
IPST
Q4 25
$122.2M
$98.2M
Q3 25
$141.8M
$420.4M
Q2 25
$166.1M
$-2.9M
Q1 25
$217.2M
$-329.0K
Q4 24
$253.0M
Q3 24
$281.2M
$-34.0M
Q2 24
$310.5M
Q1 24
$343.3M
Total Assets
CRBU
CRBU
IPST
IPST
Q4 25
$175.4M
$108.8M
Q3 25
$195.0M
$482.8M
Q2 25
$220.9M
$26.5M
Q1 25
$273.7M
$27.1M
Q4 24
$313.3M
Q3 24
$344.3M
$31.1M
Q2 24
$372.9M
Q1 24
$406.8M
Debt / Equity
CRBU
CRBU
IPST
IPST
Q4 25
0.03×
Q3 25
0.01×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRBU
CRBU
IPST
IPST
Operating Cash FlowLast quarter
$-20.8M
$-7.5M
Free Cash FlowOCF − Capex
$-21.0M
FCF MarginFCF / Revenue
-533.9%
Capex IntensityCapex / Revenue
5.5%
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-112.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRBU
CRBU
IPST
IPST
Q4 25
$-20.8M
$-7.5M
Q3 25
$-25.2M
$-4.3M
Q2 25
$-28.3M
$-1.5M
Q1 25
$-36.7M
$-2.0M
Q4 24
$-138.2M
Q3 24
$-32.7M
Q2 24
$-32.9M
Q1 24
$-37.2M
Free Cash Flow
CRBU
CRBU
IPST
IPST
Q4 25
$-21.0M
Q3 25
$-25.3M
$-4.3M
Q2 25
$-28.7M
$-1.5M
Q1 25
$-37.8M
$-2.0M
Q4 24
$-143.1M
Q3 24
$-33.3M
Q2 24
$-35.1M
Q1 24
$-38.7M
FCF Margin
CRBU
CRBU
IPST
IPST
Q4 25
-533.9%
Q3 25
-1151.0%
-144.7%
Q2 25
-1075.2%
-115.3%
Q1 25
-1605.1%
-187.6%
Q4 24
-6888.8%
Q3 24
-1646.9%
Q2 24
-1013.5%
Q1 24
-1591.2%
Capex Intensity
CRBU
CRBU
IPST
IPST
Q4 25
5.5%
0.0%
Q3 25
5.2%
1.5%
Q2 25
15.7%
0.9%
Q1 25
44.3%
1.6%
Q4 24
235.0%
Q3 24
33.3%
Q2 24
64.7%
Q1 24
59.6%
Cash Conversion
CRBU
CRBU
IPST
IPST
Q4 25
Q3 25
-0.02×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRBU
CRBU

Segment breakdown not available.

IPST
IPST

Direct To Consumer$3.0M63%
Wholesale$1.2M26%
Other$517.7K11%

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