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Side-by-side financial comparison of Charles River Laboratories (CRL) and Danaher Corporation (DHR), based on the latest 10-Q / 10-K filings. Click either name above to swap in a different company.

Danaher Corporation is the larger business by last-quarter revenue ($6.8B vs $994.2M, roughly 6.9× Charles River Laboratories). Danaher Corporation runs the higher net margin — -27.8% vs 17.5%, a 45.3% gap on every dollar of revenue. On growth, Danaher Corporation posted the faster year-over-year revenue change (4.6% vs -0.8%). Danaher Corporation produced more free cash flow last quarter ($1.7B vs $58.6M). Over the past eight quarters, Danaher Corporation's revenue compounded faster (8.6% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

Danaher Corporation is an American healthcare company headquartered in Washington, D.C.. It develops products used for advances in biotechnology, life sciences, and diagnostics. The company operates three divisions: biotechnology, which develops products for the development of therapeutics; life sciences, which develops products to identify causes of disease, new therapies, and to test and manufacture new drugs, vaccines and gene editing technologies; and diagnostics, which develops instruments,...

CRL vs DHR — Head-to-Head

Bigger by revenue
DHR
DHR
6.9× larger
DHR
$6.8B
$994.2M
CRL
Growing faster (revenue YoY)
DHR
DHR
+5.4% gap
DHR
4.6%
-0.8%
CRL
Higher net margin
DHR
DHR
45.3% more per $
DHR
17.5%
-27.8%
CRL
More free cash flow
DHR
DHR
$1.7B more FCF
DHR
$1.7B
$58.6M
CRL
Faster 2-yr revenue CAGR
DHR
DHR
Annualised
DHR
8.6%
-0.9%
CRL

Income Statement — Q4 2025 vs Q4 2025

Metric
CRL
CRL
DHR
DHR
Revenue
$994.2M
$6.8B
Net Profit
$-276.6M
$1.2B
Gross Margin
58.0%
Operating Margin
-28.5%
22.0%
Net Margin
-27.8%
17.5%
Revenue YoY
-0.8%
4.6%
Net Profit YoY
-28.9%
10.2%
EPS (diluted)
$-5.57
$1.69

Green = leading value per metric. Periods may differ when fiscal calendars don't align — see 8-quarter trend below.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history — bar widths are scaled to the larger of the two companies so you can eyeball the size gap and growth trajectory without doing math. Quarters aligned by calendar period (report date) so offset fiscal years line up.

Revenue
CRL
CRL
DHR
DHR
Q4 25
$994.2M
$6.8B
Q3 25
$1.0B
$6.1B
Q2 25
$1.0B
$5.9B
Q1 25
$984.2M
$5.7B
Q4 24
$1.0B
$6.5B
Q3 24
$1.0B
$5.8B
Q2 24
$1.0B
$5.7B
Q1 24
$1.0B
$5.8B
Net Profit
CRL
CRL
DHR
DHR
Q4 25
$-276.6M
$1.2B
Q3 25
$54.4M
$908.0M
Q2 25
$52.3M
$555.0M
Q1 25
$25.5M
$954.0M
Q4 24
$-214.5M
$1.1B
Q3 24
$69.7M
$818.0M
Q2 24
$94.1M
$907.0M
Q1 24
$73.0M
$1.1B
Gross Margin
CRL
CRL
DHR
DHR
Q4 25
58.0%
Q3 25
58.2%
Q2 25
59.3%
Q1 25
61.2%
Q4 24
59.5%
Q3 24
34.6%
58.7%
Q2 24
34.5%
59.7%
Q1 24
34.1%
60.2%
Operating Margin
CRL
CRL
DHR
DHR
Q4 25
-28.5%
22.0%
Q3 25
13.3%
19.1%
Q2 25
9.7%
12.8%
Q1 25
7.6%
22.2%
Q4 24
-16.7%
21.8%
Q3 24
11.6%
16.5%
Q2 24
14.8%
20.3%
Q1 24
12.5%
22.6%
Net Margin
CRL
CRL
DHR
DHR
Q4 25
-27.8%
17.5%
Q3 25
5.4%
15.0%
Q2 25
5.1%
9.3%
Q1 25
2.6%
16.6%
Q4 24
-21.4%
16.6%
Q3 24
6.9%
14.1%
Q2 24
9.2%
15.8%
Q1 24
7.2%
18.8%
EPS (diluted)
CRL
CRL
DHR
DHR
Q4 25
$-5.57
$1.69
Q3 25
$1.10
$1.27
Q2 25
$1.06
$0.77
Q1 25
$0.50
$1.32
Q4 24
$-4.17
$1.50
Q3 24
$1.33
$1.12
Q2 24
$1.74
$1.22
Q1 24
$1.30
$1.45

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest filing — the kind of financial-strength check premium terminals charge for.

Metric
CRL
CRL
DHR
DHR
Cash + ST InvestmentsLiquidity on hand
$213.8M
Total DebtLower is stronger
$2.1B
$18.4B
Stockholders' EquityBook value
$3.2B
$52.5B
Total Assets
$7.1B
$83.5B
Debt / EquityLower = less leverage
0.68×
0.35×

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Cash + ST Investments
CRL
CRL
DHR
DHR
Q4 25
$213.8M
Q3 25
$207.1M
Q2 25
$182.8M
Q1 25
$229.4M
Q4 24
$194.6M
Q3 24
$210.2M
Q2 24
$179.2M
Q1 24
$327.0M
Total Debt
CRL
CRL
DHR
DHR
Q4 25
$2.1B
$18.4B
Q3 25
$2.2B
$16.9B
Q2 25
$2.3B
$17.4B
Q1 25
$2.5B
$16.5B
Q4 24
$2.2B
$16.0B
Q3 24
$2.3B
$17.5B
Q2 24
$2.4B
$17.0B
Q1 24
$2.7B
$18.2B
Stockholders' Equity
CRL
CRL
DHR
DHR
Q4 25
$3.2B
$52.5B
Q3 25
$3.4B
$51.1B
Q2 25
$3.4B
$52.3B
Q1 25
$3.2B
$50.8B
Q4 24
$3.5B
$49.5B
Q3 24
$3.8B
$51.3B
Q2 24
$3.7B
$49.9B
Q1 24
$3.6B
$53.4B
Total Assets
CRL
CRL
DHR
DHR
Q4 25
$7.1B
$83.5B
Q3 25
$7.5B
$79.9B
Q2 25
$7.6B
$81.6B
Q1 25
$7.6B
$79.1B
Q4 24
$7.5B
$77.5B
Q3 24
$8.0B
$80.6B
Q2 24
$7.9B
$78.6B
Q1 24
$8.2B
$83.4B
Debt / Equity
CRL
CRL
DHR
DHR
Q4 25
0.68×
0.35×
Q3 25
0.64×
0.33×
Q2 25
0.70×
0.33×
Q1 25
0.79×
0.32×
Q4 24
0.65×
0.32×
Q3 24
0.62×
0.34×
Q2 24
0.65×
0.34×
Q1 24
0.73×
0.34×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Net income can be massaged; cash flow is harder to fake.

Metric
CRL
CRL
DHR
DHR
Operating Cash FlowLast quarter
$147.5M
$2.1B
Free Cash FlowOCF − Capex
$58.6M
$1.7B
FCF MarginFCF / Revenue
5.9%
25.5%
Capex IntensityCapex / Revenue; lower = less reinvestment burden
8.9%
5.4%
Cash ConversionOCF / Net Profit; >1× = earnings back up with cash
1.77×
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$5.3B

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Operating Cash Flow
CRL
CRL
DHR
DHR
Q4 25
$147.5M
$2.1B
Q3 25
$213.8M
$1.7B
Q2 25
$204.6M
$1.3B
Q1 25
$171.7M
$1.3B
Q4 24
$159.4M
$2.0B
Q3 24
$251.8M
$1.5B
Q2 24
$193.5M
$1.4B
Q1 24
$129.9M
$1.7B
Free Cash Flow
CRL
CRL
DHR
DHR
Q4 25
$58.6M
$1.7B
Q3 25
$178.2M
$1.4B
Q2 25
$169.3M
$1.1B
Q1 25
$112.4M
$1.1B
Q4 24
$83.7M
$1.5B
Q3 24
$213.1M
$1.2B
Q2 24
$154.0M
$1.1B
Q1 24
$50.7M
$1.4B
FCF Margin
CRL
CRL
DHR
DHR
Q4 25
5.9%
25.5%
Q3 25
17.7%
22.6%
Q2 25
16.4%
18.4%
Q1 25
11.4%
18.4%
Q4 24
8.4%
23.0%
Q3 24
21.1%
21.0%
Q2 24
15.0%
19.7%
Q1 24
5.0%
25.0%
Capex Intensity
CRL
CRL
DHR
DHR
Q4 25
8.9%
5.4%
Q3 25
3.5%
4.8%
Q2 25
3.4%
4.2%
Q1 25
6.0%
4.3%
Q4 24
7.5%
7.9%
Q3 24
3.8%
5.1%
Q2 24
3.8%
5.0%
Q1 24
7.8%
5.0%
Cash Conversion
CRL
CRL
DHR
DHR
Q4 25
1.77×
Q3 25
3.93×
1.83×
Q2 25
3.91×
2.41×
Q1 25
6.74×
1.36×
Q4 24
1.86×
Q3 24
3.61×
1.85×
Q2 24
2.06×
1.56×
Q1 24
1.78×
1.60×

Financial Flow Comparison

Sankey diagram of revenue → gross profit → operating profit → net profit for each company. Charts shown full-width and stacked so both segment hierarchies are readable side-by-side on desktop and mobile.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

DHR
DHR

Segment breakdown not available.

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