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Side-by-side financial comparison of Charles River Laboratories (CRL) and EPAM Systems (EPAM). Click either name above to swap in a different company.

EPAM Systems is the larger business by last-quarter revenue ($1.4B vs $994.2M, roughly 1.4× Charles River Laboratories). EPAM Systems runs the higher net margin — 7.8% vs -27.8%, a 35.6% gap on every dollar of revenue. On growth, EPAM Systems posted the faster year-over-year revenue change (12.8% vs -0.8%). EPAM Systems produced more free cash flow last quarter ($268.1M vs $58.6M). Over the past eight quarters, EPAM Systems's revenue compounded faster (9.9% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

EPAM Systems, Inc. is an American company that specializes in software engineering services, digital platform engineering, and digital product design, operating out of Newtown, Pennsylvania. EPAM is a founding member of the MACH Alliance.

CRL vs EPAM — Head-to-Head

Bigger by revenue
EPAM
EPAM
1.4× larger
EPAM
$1.4B
$994.2M
CRL
Growing faster (revenue YoY)
EPAM
EPAM
+13.6% gap
EPAM
12.8%
-0.8%
CRL
Higher net margin
EPAM
EPAM
35.6% more per $
EPAM
7.8%
-27.8%
CRL
More free cash flow
EPAM
EPAM
$209.5M more FCF
EPAM
$268.1M
$58.6M
CRL
Faster 2-yr revenue CAGR
EPAM
EPAM
Annualised
EPAM
9.9%
-0.9%
CRL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CRL
CRL
EPAM
EPAM
Revenue
$994.2M
$1.4B
Net Profit
$-276.6M
$109.4M
Gross Margin
30.1%
Operating Margin
-28.5%
10.6%
Net Margin
-27.8%
7.8%
Revenue YoY
-0.8%
12.8%
Net Profit YoY
-28.9%
5.9%
EPS (diluted)
$-5.57
$1.97

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRL
CRL
EPAM
EPAM
Q4 25
$994.2M
$1.4B
Q3 25
$1.0B
$1.4B
Q2 25
$1.0B
$1.4B
Q1 25
$984.2M
$1.3B
Q4 24
$1.0B
$1.2B
Q3 24
$1.0B
$1.2B
Q2 24
$1.0B
$1.1B
Q1 24
$1.0B
$1.2B
Net Profit
CRL
CRL
EPAM
EPAM
Q4 25
$-276.6M
$109.4M
Q3 25
$54.4M
$106.8M
Q2 25
$52.3M
$88.0M
Q1 25
$25.5M
$73.5M
Q4 24
$-214.5M
$103.3M
Q3 24
$69.7M
$136.3M
Q2 24
$94.1M
$98.6M
Q1 24
$73.0M
$116.2M
Gross Margin
CRL
CRL
EPAM
EPAM
Q4 25
30.1%
Q3 25
29.5%
Q2 25
28.8%
Q1 25
26.9%
Q4 24
30.4%
Q3 24
34.6%
34.6%
Q2 24
34.5%
29.3%
Q1 24
34.1%
28.4%
Operating Margin
CRL
CRL
EPAM
EPAM
Q4 25
-28.5%
10.6%
Q3 25
13.3%
10.4%
Q2 25
9.7%
9.3%
Q1 25
7.6%
7.6%
Q4 24
-16.7%
10.9%
Q3 24
11.6%
15.2%
Q2 24
14.8%
10.5%
Q1 24
12.5%
9.5%
Net Margin
CRL
CRL
EPAM
EPAM
Q4 25
-27.8%
7.8%
Q3 25
5.4%
7.7%
Q2 25
5.1%
6.5%
Q1 25
2.6%
5.6%
Q4 24
-21.4%
8.3%
Q3 24
6.9%
11.7%
Q2 24
9.2%
8.6%
Q1 24
7.2%
10.0%
EPS (diluted)
CRL
CRL
EPAM
EPAM
Q4 25
$-5.57
$1.97
Q3 25
$1.10
$1.91
Q2 25
$1.06
$1.56
Q1 25
$0.50
$1.28
Q4 24
$-4.17
$1.80
Q3 24
$1.33
$2.37
Q2 24
$1.74
$1.70
Q1 24
$1.30
$1.97

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRL
CRL
EPAM
EPAM
Cash + ST InvestmentsLiquidity on hand
$213.8M
$1.3B
Total DebtLower is stronger
$2.1B
Stockholders' EquityBook value
$3.2B
$3.7B
Total Assets
$7.1B
$4.9B
Debt / EquityLower = less leverage
0.68×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRL
CRL
EPAM
EPAM
Q4 25
$213.8M
$1.3B
Q3 25
$207.1M
$1.2B
Q2 25
$182.8M
$1.0B
Q1 25
$229.4M
$1.2B
Q4 24
$194.6M
$1.3B
Q3 24
$210.2M
$2.1B
Q2 24
$179.2M
$1.8B
Q1 24
$327.0M
$2.0B
Total Debt
CRL
CRL
EPAM
EPAM
Q4 25
$2.1B
Q3 25
$2.2B
Q2 25
$2.3B
Q1 25
$2.5B
Q4 24
$2.2B
Q3 24
$2.3B
Q2 24
$2.4B
Q1 24
$2.7B
Stockholders' Equity
CRL
CRL
EPAM
EPAM
Q4 25
$3.2B
$3.7B
Q3 25
$3.4B
$3.7B
Q2 25
$3.4B
$3.7B
Q1 25
$3.2B
$3.6B
Q4 24
$3.5B
$3.6B
Q3 24
$3.8B
$3.6B
Q2 24
$3.7B
$3.4B
Q1 24
$3.6B
$3.5B
Total Assets
CRL
CRL
EPAM
EPAM
Q4 25
$7.1B
$4.9B
Q3 25
$7.5B
$4.8B
Q2 25
$7.6B
$4.7B
Q1 25
$7.6B
$4.7B
Q4 24
$7.5B
$4.8B
Q3 24
$8.0B
$4.5B
Q2 24
$7.9B
$4.2B
Q1 24
$8.2B
$4.4B
Debt / Equity
CRL
CRL
EPAM
EPAM
Q4 25
0.68×
Q3 25
0.64×
Q2 25
0.70×
Q1 25
0.79×
Q4 24
0.65×
Q3 24
0.62×
Q2 24
0.65×
Q1 24
0.73×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRL
CRL
EPAM
EPAM
Operating Cash FlowLast quarter
$147.5M
$282.9M
Free Cash FlowOCF − Capex
$58.6M
$268.1M
FCF MarginFCF / Revenue
5.9%
19.0%
Capex IntensityCapex / Revenue
8.9%
1.1%
Cash ConversionOCF / Net Profit
2.59×
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$612.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRL
CRL
EPAM
EPAM
Q4 25
$147.5M
$282.9M
Q3 25
$213.8M
$294.7M
Q2 25
$204.6M
$53.2M
Q1 25
$171.7M
$24.2M
Q4 24
$159.4M
$130.3M
Q3 24
$251.8M
$242.0M
Q2 24
$193.5M
$57.0M
Q1 24
$129.9M
$129.9M
Free Cash Flow
CRL
CRL
EPAM
EPAM
Q4 25
$58.6M
$268.1M
Q3 25
$178.2M
$286.4M
Q2 25
$169.3M
$43.4M
Q1 25
$112.4M
$14.8M
Q4 24
$83.7M
$114.5M
Q3 24
$213.1M
$237.0M
Q2 24
$154.0M
$52.3M
Q1 24
$50.7M
$123.2M
FCF Margin
CRL
CRL
EPAM
EPAM
Q4 25
5.9%
19.0%
Q3 25
17.7%
20.5%
Q2 25
16.4%
3.2%
Q1 25
11.4%
1.1%
Q4 24
8.4%
9.2%
Q3 24
21.1%
20.3%
Q2 24
15.0%
4.6%
Q1 24
5.0%
10.6%
Capex Intensity
CRL
CRL
EPAM
EPAM
Q4 25
8.9%
1.1%
Q3 25
3.5%
0.6%
Q2 25
3.4%
0.7%
Q1 25
6.0%
0.7%
Q4 24
7.5%
1.3%
Q3 24
3.8%
0.4%
Q2 24
3.8%
0.4%
Q1 24
7.8%
0.6%
Cash Conversion
CRL
CRL
EPAM
EPAM
Q4 25
2.59×
Q3 25
3.93×
2.76×
Q2 25
3.91×
0.60×
Q1 25
6.74×
0.33×
Q4 24
1.26×
Q3 24
3.61×
1.77×
Q2 24
2.06×
0.58×
Q1 24
1.78×
1.12×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

EPAM
EPAM

Segment breakdown not available.

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