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Side-by-side financial comparison of Charles River Laboratories (CRL) and RXO, Inc. (RXO). Click either name above to swap in a different company.

RXO, Inc. is the larger business by last-quarter revenue ($1.5B vs $994.2M, roughly 1.5× Charles River Laboratories). RXO, Inc. runs the higher net margin — -3.1% vs -27.8%, a 24.7% gap on every dollar of revenue. On growth, Charles River Laboratories posted the faster year-over-year revenue change (-0.8% vs -11.9%). Charles River Laboratories produced more free cash flow last quarter ($58.6M vs $-9.0M). Over the past eight quarters, RXO, Inc.'s revenue compounded faster (26.8% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

RXO, Inc. is a leading transportation and logistics solutions provider headquartered in the United States. Its core service portfolio includes freight brokerage, last-mile delivery for heavy and bulky goods, managed transportation services, and end-to-end supply chain optimization support, primarily catering to clients across the North American manufacturing, retail, and e-commerce segments.

CRL vs RXO — Head-to-Head

Bigger by revenue
RXO
RXO
1.5× larger
RXO
$1.5B
$994.2M
CRL
Growing faster (revenue YoY)
CRL
CRL
+11.0% gap
CRL
-0.8%
-11.9%
RXO
Higher net margin
RXO
RXO
24.7% more per $
RXO
-3.1%
-27.8%
CRL
More free cash flow
CRL
CRL
$67.6M more FCF
CRL
$58.6M
$-9.0M
RXO
Faster 2-yr revenue CAGR
RXO
RXO
Annualised
RXO
26.8%
-0.9%
CRL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CRL
CRL
RXO
RXO
Revenue
$994.2M
$1.5B
Net Profit
$-276.6M
$-46.0M
Gross Margin
Operating Margin
-28.5%
-2.9%
Net Margin
-27.8%
-3.1%
Revenue YoY
-0.8%
-11.9%
Net Profit YoY
-28.9%
-84.0%
EPS (diluted)
$-5.57
$-0.28

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRL
CRL
RXO
RXO
Q4 25
$994.2M
$1.5B
Q3 25
$1.0B
$1.4B
Q2 25
$1.0B
$1.4B
Q1 25
$984.2M
$1.4B
Q4 24
$1.0B
$1.7B
Q3 24
$1.0B
$1.0B
Q2 24
$1.0B
$930.0M
Q1 24
$1.0B
$913.0M
Net Profit
CRL
CRL
RXO
RXO
Q4 25
$-276.6M
$-46.0M
Q3 25
$54.4M
$-14.0M
Q2 25
$52.3M
$-9.0M
Q1 25
$25.5M
$-31.0M
Q4 24
$-214.5M
$-25.0M
Q3 24
$69.7M
$-243.0M
Q2 24
$94.1M
$-7.0M
Q1 24
$73.0M
$-15.0M
Gross Margin
CRL
CRL
RXO
RXO
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
34.6%
Q2 24
34.5%
Q1 24
34.1%
Operating Margin
CRL
CRL
RXO
RXO
Q4 25
-28.5%
-2.9%
Q3 25
13.3%
-0.5%
Q2 25
9.7%
Q1 25
7.6%
-2.1%
Q4 24
-16.7%
-1.4%
Q3 24
11.6%
-1.9%
Q2 24
14.8%
Q1 24
12.5%
-1.3%
Net Margin
CRL
CRL
RXO
RXO
Q4 25
-27.8%
-3.1%
Q3 25
5.4%
-1.0%
Q2 25
5.1%
-0.6%
Q1 25
2.6%
-2.2%
Q4 24
-21.4%
-1.5%
Q3 24
6.9%
-23.4%
Q2 24
9.2%
-0.8%
Q1 24
7.2%
-1.6%
EPS (diluted)
CRL
CRL
RXO
RXO
Q4 25
$-5.57
$-0.28
Q3 25
$1.10
$-0.08
Q2 25
$1.06
$-0.05
Q1 25
$0.50
$-0.18
Q4 24
$-4.17
$-0.17
Q3 24
$1.33
$-1.81
Q2 24
$1.74
$-0.06
Q1 24
$1.30
$-0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRL
CRL
RXO
RXO
Cash + ST InvestmentsLiquidity on hand
$213.8M
$17.0M
Total DebtLower is stronger
$2.1B
$387.0M
Stockholders' EquityBook value
$3.2B
$1.5B
Total Assets
$7.1B
$3.3B
Debt / EquityLower = less leverage
0.68×
0.25×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRL
CRL
RXO
RXO
Q4 25
$213.8M
$17.0M
Q3 25
$207.1M
$25.0M
Q2 25
$182.8M
$18.0M
Q1 25
$229.4M
$16.0M
Q4 24
$194.6M
$35.0M
Q3 24
$210.2M
$55.0M
Q2 24
$179.2M
$7.0M
Q1 24
$327.0M
$7.0M
Total Debt
CRL
CRL
RXO
RXO
Q4 25
$2.1B
$387.0M
Q3 25
$2.2B
$387.0M
Q2 25
$2.3B
$387.0M
Q1 25
$2.5B
$387.0M
Q4 24
$2.2B
$351.0M
Q3 24
$2.3B
$352.0M
Q2 24
$2.4B
$370.0M
Q1 24
$2.7B
$351.0M
Stockholders' Equity
CRL
CRL
RXO
RXO
Q4 25
$3.2B
$1.5B
Q3 25
$3.4B
$1.6B
Q2 25
$3.4B
$1.6B
Q1 25
$3.2B
$1.6B
Q4 24
$3.5B
$1.6B
Q3 24
$3.8B
$1.7B
Q2 24
$3.7B
$579.0M
Q1 24
$3.6B
$582.0M
Total Assets
CRL
CRL
RXO
RXO
Q4 25
$7.1B
$3.3B
Q3 25
$7.5B
$3.2B
Q2 25
$7.6B
$3.2B
Q1 25
$7.6B
$3.3B
Q4 24
$7.5B
$3.4B
Q3 24
$8.0B
$3.4B
Q2 24
$7.9B
$1.8B
Q1 24
$8.2B
$1.8B
Debt / Equity
CRL
CRL
RXO
RXO
Q4 25
0.68×
0.25×
Q3 25
0.64×
0.24×
Q2 25
0.70×
0.24×
Q1 25
0.79×
0.24×
Q4 24
0.65×
0.22×
Q3 24
0.62×
0.21×
Q2 24
0.65×
0.64×
Q1 24
0.73×
0.60×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRL
CRL
RXO
RXO
Operating Cash FlowLast quarter
$147.5M
$7.0M
Free Cash FlowOCF − Capex
$58.6M
$-9.0M
FCF MarginFCF / Revenue
5.9%
-0.6%
Capex IntensityCapex / Revenue
8.9%
1.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$-8.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRL
CRL
RXO
RXO
Q4 25
$147.5M
$7.0M
Q3 25
$213.8M
$23.0M
Q2 25
$204.6M
$23.0M
Q1 25
$171.7M
$-2.0M
Q4 24
$159.4M
$-7.0M
Q3 24
$251.8M
$-7.0M
Q2 24
$193.5M
$-5.0M
Q1 24
$129.9M
$7.0M
Free Cash Flow
CRL
CRL
RXO
RXO
Q4 25
$58.6M
$-9.0M
Q3 25
$178.2M
$9.0M
Q2 25
$169.3M
$9.0M
Q1 25
$112.4M
$-17.0M
Q4 24
$83.7M
$-19.0M
Q3 24
$213.1M
$-18.0M
Q2 24
$154.0M
$-16.0M
Q1 24
$50.7M
$-4.0M
FCF Margin
CRL
CRL
RXO
RXO
Q4 25
5.9%
-0.6%
Q3 25
17.7%
0.6%
Q2 25
16.4%
0.6%
Q1 25
11.4%
-1.2%
Q4 24
8.4%
-1.1%
Q3 24
21.1%
-1.7%
Q2 24
15.0%
-1.7%
Q1 24
5.0%
-0.4%
Capex Intensity
CRL
CRL
RXO
RXO
Q4 25
8.9%
1.1%
Q3 25
3.5%
1.0%
Q2 25
3.4%
1.0%
Q1 25
6.0%
1.0%
Q4 24
7.5%
0.7%
Q3 24
3.8%
1.1%
Q2 24
3.8%
1.2%
Q1 24
7.8%
1.2%
Cash Conversion
CRL
CRL
RXO
RXO
Q4 25
Q3 25
3.93×
Q2 25
3.91×
Q1 25
6.74×
Q4 24
Q3 24
3.61×
Q2 24
2.06×
Q1 24
1.78×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

RXO
RXO

Retail Sector$546.0M37%
Last Mile$298.0M20%
Food And Beverage Sector$225.0M15%
Other Sector$185.0M13%
Managed Transportation$133.0M9%
Automotive Sector$93.0M6%

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