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Side-by-side financial comparison of Charles River Laboratories (CRL) and Tradeweb Markets Inc. (TW). Click either name above to swap in a different company.

Charles River Laboratories is the larger business by last-quarter revenue ($994.2M vs $617.8M, roughly 1.6× Tradeweb Markets Inc.). Tradeweb Markets Inc. runs the higher net margin — 37.7% vs -27.8%, a 65.6% gap on every dollar of revenue. On growth, Tradeweb Markets Inc. posted the faster year-over-year revenue change (21.2% vs -0.8%). Charles River Laboratories produced more free cash flow last quarter ($58.6M vs $2.0M). Over the past eight quarters, Tradeweb Markets Inc.'s revenue compounded faster (23.5% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

Tradeweb Markets Inc., headquartered in New York City, operates electronic trading platforms primarily used by institutional investors to trade fixed income products, ETFs, and derivatives. It has over 3,000 customers including banks, asset managers, central banks, pension funds, and insurance companies. In 2024, 83% of the company's revenue was from transaction fees and commissions and 17% was from subscription fees. In 2024, 52% of revenue came from products related to rates, 27% of revenue...

CRL vs TW — Head-to-Head

Bigger by revenue
CRL
CRL
1.6× larger
CRL
$994.2M
$617.8M
TW
Growing faster (revenue YoY)
TW
TW
+22.0% gap
TW
21.2%
-0.8%
CRL
Higher net margin
TW
TW
65.6% more per $
TW
37.7%
-27.8%
CRL
More free cash flow
CRL
CRL
$56.5M more FCF
CRL
$58.6M
$2.0M
TW
Faster 2-yr revenue CAGR
TW
TW
Annualised
TW
23.5%
-0.9%
CRL

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
CRL
CRL
TW
TW
Revenue
$994.2M
$617.8M
Net Profit
$-276.6M
$233.2M
Gross Margin
Operating Margin
-28.5%
46.5%
Net Margin
-27.8%
37.7%
Revenue YoY
-0.8%
21.2%
Net Profit YoY
-28.9%
38.5%
EPS (diluted)
$-5.57
$0.96

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRL
CRL
TW
TW
Q1 26
$617.8M
Q4 25
$994.2M
$521.2M
Q3 25
$1.0B
$508.6M
Q2 25
$1.0B
$513.0M
Q1 25
$984.2M
$509.7M
Q4 24
$1.0B
$463.3M
Q3 24
$1.0B
$448.9M
Q2 24
$1.0B
$405.0M
Net Profit
CRL
CRL
TW
TW
Q1 26
$233.2M
Q4 25
$-276.6M
$325.0M
Q3 25
$54.4M
$185.6M
Q2 25
$52.3M
$153.8M
Q1 25
$25.5M
$148.4M
Q4 24
$-214.5M
$142.2M
Q3 24
$69.7M
$113.9M
Q2 24
$94.1M
$119.2M
Gross Margin
CRL
CRL
TW
TW
Q1 26
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
34.6%
Q2 24
34.5%
Operating Margin
CRL
CRL
TW
TW
Q1 26
46.5%
Q4 25
-28.5%
42.4%
Q3 25
13.3%
41.4%
Q2 25
9.7%
39.0%
Q1 25
7.6%
40.0%
Q4 24
-16.7%
40.7%
Q3 24
11.6%
35.5%
Q2 24
14.8%
40.1%
Net Margin
CRL
CRL
TW
TW
Q1 26
37.7%
Q4 25
-27.8%
62.4%
Q3 25
5.4%
36.5%
Q2 25
5.1%
30.0%
Q1 25
2.6%
29.1%
Q4 24
-21.4%
30.7%
Q3 24
6.9%
25.4%
Q2 24
9.2%
29.4%
EPS (diluted)
CRL
CRL
TW
TW
Q1 26
$0.96
Q4 25
$-5.57
$1.52
Q3 25
$1.10
$0.86
Q2 25
$1.06
$0.71
Q1 25
$0.50
$0.69
Q4 24
$-4.17
$0.66
Q3 24
$1.33
$0.53
Q2 24
$1.74
$0.55

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRL
CRL
TW
TW
Cash + ST InvestmentsLiquidity on hand
$213.8M
Total DebtLower is stronger
$2.1B
Stockholders' EquityBook value
$3.2B
Total Assets
$7.1B
Debt / EquityLower = less leverage
0.68×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRL
CRL
TW
TW
Q1 26
Q4 25
$213.8M
$2.1B
Q3 25
$207.1M
$1.9B
Q2 25
$182.8M
$1.6B
Q1 25
$229.4M
$1.3B
Q4 24
$194.6M
$1.3B
Q3 24
$210.2M
$1.2B
Q2 24
$179.2M
$1.7B
Total Debt
CRL
CRL
TW
TW
Q1 26
Q4 25
$2.1B
Q3 25
$2.2B
Q2 25
$2.3B
Q1 25
$2.5B
Q4 24
$2.2B
Q3 24
$2.3B
Q2 24
$2.4B
Stockholders' Equity
CRL
CRL
TW
TW
Q1 26
Q4 25
$3.2B
$6.5B
Q3 25
$3.4B
$6.3B
Q2 25
$3.4B
$6.1B
Q1 25
$3.2B
$5.9B
Q4 24
$3.5B
$5.8B
Q3 24
$3.8B
$5.7B
Q2 24
$3.7B
$5.6B
Total Assets
CRL
CRL
TW
TW
Q1 26
Q4 25
$7.1B
$8.2B
Q3 25
$7.5B
$8.0B
Q2 25
$7.6B
$8.1B
Q1 25
$7.6B
$7.4B
Q4 24
$7.5B
$7.3B
Q3 24
$8.0B
$7.3B
Q2 24
$7.9B
$7.3B
Debt / Equity
CRL
CRL
TW
TW
Q1 26
Q4 25
0.68×
Q3 25
0.64×
Q2 25
0.70×
Q1 25
0.79×
Q4 24
0.65×
Q3 24
0.62×
Q2 24
0.65×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRL
CRL
TW
TW
Operating Cash FlowLast quarter
$147.5M
Free Cash FlowOCF − Capex
$58.6M
$2.0M
FCF MarginFCF / Revenue
5.9%
0.3%
Capex IntensityCapex / Revenue
8.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$1.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRL
CRL
TW
TW
Q1 26
Q4 25
$147.5M
$355.9M
Q3 25
$213.8M
$342.3M
Q2 25
$204.6M
$409.2M
Q1 25
$171.7M
$60.2M
Q4 24
$159.4M
$282.0M
Q3 24
$251.8M
$292.1M
Q2 24
$193.5M
$285.7M
Free Cash Flow
CRL
CRL
TW
TW
Q1 26
$2.0M
Q4 25
$58.6M
$336.5M
Q3 25
$178.2M
$328.3M
Q2 25
$169.3M
$403.7M
Q1 25
$112.4M
$58.6M
Q4 24
$83.7M
$256.8M
Q3 24
$213.1M
$287.8M
Q2 24
$154.0M
$280.8M
FCF Margin
CRL
CRL
TW
TW
Q1 26
0.3%
Q4 25
5.9%
64.6%
Q3 25
17.7%
64.5%
Q2 25
16.4%
78.7%
Q1 25
11.4%
11.5%
Q4 24
8.4%
55.4%
Q3 24
21.1%
64.1%
Q2 24
15.0%
69.4%
Capex Intensity
CRL
CRL
TW
TW
Q1 26
Q4 25
8.9%
3.7%
Q3 25
3.5%
2.8%
Q2 25
3.4%
1.1%
Q1 25
6.0%
0.3%
Q4 24
7.5%
5.4%
Q3 24
3.8%
1.0%
Q2 24
3.8%
1.2%
Cash Conversion
CRL
CRL
TW
TW
Q1 26
Q4 25
1.10×
Q3 25
3.93×
1.84×
Q2 25
3.91×
2.66×
Q1 25
6.74×
0.41×
Q4 24
1.98×
Q3 24
3.61×
2.56×
Q2 24
2.06×
2.40×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

TW
TW

Transaction fees and commissions$523.8M85%
Subscription fees$60.3M10%
LSEG market data fees$26.7M4%

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