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Side-by-side financial comparison of Charles River Laboratories (CRL) and TWILIO INC (TWLO). Click either name above to swap in a different company.
TWILIO INC is the larger business by last-quarter revenue ($1.4B vs $995.8M, roughly 1.4× Charles River Laboratories). TWILIO INC runs the higher net margin — 6.4% vs -1.5%, a 7.9% gap on every dollar of revenue. Over the past eight quarters, TWILIO INC's revenue compounded faster (14.0% CAGR vs -1.5%).
Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.
Twilio Inc. is an American cloud communications company based in San Francisco, California, which provides programmable communication tools for making and receiving phone calls, sending and receiving text messages, and performing other communication functions using its web service APIs.
CRL vs TWLO — Head-to-Head
Income Statement — Q1 FY2026 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $995.8M | $1.4B |
| Net Profit | $-14.8M | $90.0M |
| Gross Margin | — | 48.6% |
| Operating Margin | 12.0% | 7.7% |
| Net Margin | -1.5% | 6.4% |
| Revenue YoY | 1.2% | — |
| Net Profit YoY | -157.2% | — |
| EPS (diluted) | $-0.30 | $0.57 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $995.8M | $1.4B | ||
| Q4 25 | $994.2M | $1.4B | ||
| Q3 25 | $1.0B | $1.3B | ||
| Q2 25 | $1.0B | $1.2B | ||
| Q1 25 | $984.2M | $1.2B | ||
| Q4 24 | $1.0B | $1.2B | ||
| Q3 24 | $1.0B | $1.1B | ||
| Q2 24 | $1.0B | $1.1B |
| Q1 26 | $-14.8M | $90.0M | ||
| Q4 25 | $-276.6M | $-45.9M | ||
| Q3 25 | $54.4M | $37.2M | ||
| Q2 25 | $52.3M | $22.4M | ||
| Q1 25 | $25.5M | $20.0M | ||
| Q4 24 | $-214.5M | $-12.5M | ||
| Q3 24 | $69.7M | $-9.7M | ||
| Q2 24 | $94.1M | $-31.9M |
| Q1 26 | — | 48.6% | ||
| Q4 25 | — | 48.5% | ||
| Q3 25 | — | 48.6% | ||
| Q2 25 | — | 49.1% | ||
| Q1 25 | — | 49.6% | ||
| Q4 24 | — | 50.2% | ||
| Q3 24 | 34.6% | 51.0% | ||
| Q2 24 | 34.5% | 51.3% |
| Q1 26 | 12.0% | 7.7% | ||
| Q4 25 | -28.5% | 4.2% | ||
| Q3 25 | 13.3% | 3.1% | ||
| Q2 25 | 9.7% | 3.0% | ||
| Q1 25 | 7.6% | 2.0% | ||
| Q4 24 | -16.7% | 1.1% | ||
| Q3 24 | 11.6% | -0.4% | ||
| Q2 24 | 14.8% | -1.8% |
| Q1 26 | -1.5% | 6.4% | ||
| Q4 25 | -27.8% | -3.4% | ||
| Q3 25 | 5.4% | 2.9% | ||
| Q2 25 | 5.1% | 1.8% | ||
| Q1 25 | 2.6% | 1.7% | ||
| Q4 24 | -21.4% | -1.0% | ||
| Q3 24 | 6.9% | -0.9% | ||
| Q2 24 | 9.2% | -2.9% |
| Q1 26 | $-0.30 | $0.57 | ||
| Q4 25 | $-5.57 | $-0.28 | ||
| Q3 25 | $1.10 | $0.23 | ||
| Q2 25 | $1.06 | $0.14 | ||
| Q1 25 | $0.50 | $0.12 | ||
| Q4 24 | $-4.17 | $-0.10 | ||
| Q3 24 | $1.33 | $-0.06 | ||
| Q2 24 | $1.74 | $-0.19 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $191.8M | $542.0M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $2.9B | $7.8B |
| Total Assets | $7.7B | $9.6B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $191.8M | $542.0M | ||
| Q4 25 | $213.8M | $682.3M | ||
| Q3 25 | $207.1M | $734.8M | ||
| Q2 25 | $182.8M | $969.2M | ||
| Q1 25 | $229.4M | $467.1M | ||
| Q4 24 | $194.6M | $421.3M | ||
| Q3 24 | $210.2M | $584.0M | ||
| Q2 24 | $179.2M | $755.1M |
| Q1 26 | — | — | ||
| Q4 25 | $2.1B | $992.3M | ||
| Q3 25 | $2.2B | $991.9M | ||
| Q2 25 | $2.3B | $991.4M | ||
| Q1 25 | $2.5B | $991.0M | ||
| Q4 24 | $2.2B | $990.6M | ||
| Q3 24 | $2.3B | $990.2M | ||
| Q2 24 | $2.4B | $989.8M |
| Q1 26 | $2.9B | $7.8B | ||
| Q4 25 | $3.2B | $7.8B | ||
| Q3 25 | $3.4B | $7.9B | ||
| Q2 25 | $3.4B | $8.0B | ||
| Q1 25 | $3.2B | $8.0B | ||
| Q4 24 | $3.5B | $8.0B | ||
| Q3 24 | $3.8B | $8.2B | ||
| Q2 24 | $3.7B | $8.7B |
| Q1 26 | $7.7B | $9.6B | ||
| Q4 25 | $7.1B | $9.8B | ||
| Q3 25 | $7.5B | $9.7B | ||
| Q2 25 | $7.6B | $9.8B | ||
| Q1 25 | $7.6B | $9.8B | ||
| Q4 24 | $7.5B | $9.9B | ||
| Q3 24 | $8.0B | $10.0B | ||
| Q2 24 | $7.9B | $10.5B |
| Q1 26 | — | — | ||
| Q4 25 | 0.68× | 0.13× | ||
| Q3 25 | 0.64× | 0.13× | ||
| Q2 25 | 0.70× | 0.12× | ||
| Q1 25 | 0.79× | 0.12× | ||
| Q4 24 | 0.65× | 0.12× | ||
| Q3 24 | 0.62× | 0.12× | ||
| Q2 24 | 0.65× | 0.11× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $41.1M | $153.0M |
| Free Cash FlowOCF − Capex | — | $132.0M |
| FCF MarginFCF / Revenue | — | 9.4% |
| Capex IntensityCapex / Revenue | 5.6% | — |
| Cash ConversionOCF / Net Profit | — | 1.70× |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $41.1M | $153.0M | ||
| Q4 25 | $147.5M | $271.6M | ||
| Q3 25 | $213.8M | $263.6M | ||
| Q2 25 | $204.6M | $277.1M | ||
| Q1 25 | $171.7M | $191.0M | ||
| Q4 24 | $159.4M | $108.4M | ||
| Q3 24 | $251.8M | $204.3M | ||
| Q2 24 | $193.5M | $213.3M |
| Q1 26 | — | $132.0M | ||
| Q4 25 | $58.6M | — | ||
| Q3 25 | $178.2M | — | ||
| Q2 25 | $169.3M | — | ||
| Q1 25 | $112.4M | — | ||
| Q4 24 | $83.7M | — | ||
| Q3 24 | $213.1M | — | ||
| Q2 24 | $154.0M | — |
| Q1 26 | — | 9.4% | ||
| Q4 25 | 5.9% | — | ||
| Q3 25 | 17.7% | — | ||
| Q2 25 | 16.4% | — | ||
| Q1 25 | 11.4% | — | ||
| Q4 24 | 8.4% | — | ||
| Q3 24 | 21.1% | — | ||
| Q2 24 | 15.0% | — |
| Q1 26 | 5.6% | — | ||
| Q4 25 | 8.9% | — | ||
| Q3 25 | 3.5% | — | ||
| Q2 25 | 3.4% | — | ||
| Q1 25 | 6.0% | — | ||
| Q4 24 | 7.5% | — | ||
| Q3 24 | 3.8% | — | ||
| Q2 24 | 3.8% | — |
| Q1 26 | — | 1.70× | ||
| Q4 25 | — | — | ||
| Q3 25 | 3.93× | 7.08× | ||
| Q2 25 | 3.91× | 12.36× | ||
| Q1 25 | 6.74× | 9.54× | ||
| Q4 24 | — | — | ||
| Q3 24 | 3.61× | — | ||
| Q2 24 | 2.06× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CRL
| Service revenue | $798.2M | 80% |
| Product revenue | $197.7M | 20% |
TWLO
Segment breakdown not available.
