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Side-by-side financial comparison of Charles River Laboratories (CRL) and DENTSPLY SIRONA Inc. (XRAY). Click either name above to swap in a different company.

Charles River Laboratories is the larger business by last-quarter revenue ($994.2M vs $961.0M, roughly 1.0× DENTSPLY SIRONA Inc.). DENTSPLY SIRONA Inc. runs the higher net margin — -15.2% vs -27.8%, a 12.6% gap on every dollar of revenue. On growth, DENTSPLY SIRONA Inc. posted the faster year-over-year revenue change (6.2% vs -0.8%). DENTSPLY SIRONA Inc. produced more free cash flow last quarter ($60.0M vs $58.6M). Over the past eight quarters, DENTSPLY SIRONA Inc.'s revenue compounded faster (0.4% CAGR vs -0.9%).

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices.

Dentsply Sirona Inc. is an American dental equipment manufacturer and dental consumables producer that markets its products in over 120 countries. It has factories in 21 countries. The present company is largely the result of a merger in 1993 in which Gendex Corporation acquired Dentsply International Inc. for $590 million.

CRL vs XRAY — Head-to-Head

Bigger by revenue
CRL
CRL
1.0× larger
CRL
$994.2M
$961.0M
XRAY
Growing faster (revenue YoY)
XRAY
XRAY
+7.0% gap
XRAY
6.2%
-0.8%
CRL
Higher net margin
XRAY
XRAY
12.6% more per $
XRAY
-15.2%
-27.8%
CRL
More free cash flow
XRAY
XRAY
$1.4M more FCF
XRAY
$60.0M
$58.6M
CRL
Faster 2-yr revenue CAGR
XRAY
XRAY
Annualised
XRAY
0.4%
-0.9%
CRL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CRL
CRL
XRAY
XRAY
Revenue
$994.2M
$961.0M
Net Profit
$-276.6M
$-146.0M
Gross Margin
46.1%
Operating Margin
-28.5%
-14.5%
Net Margin
-27.8%
-15.2%
Revenue YoY
-0.8%
6.2%
Net Profit YoY
-28.9%
66.0%
EPS (diluted)
$-5.57
$-0.74

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRL
CRL
XRAY
XRAY
Q4 25
$994.2M
$961.0M
Q3 25
$1.0B
$904.0M
Q2 25
$1.0B
$936.0M
Q1 25
$984.2M
$879.0M
Q4 24
$1.0B
$905.0M
Q3 24
$1.0B
$951.0M
Q2 24
$1.0B
$984.0M
Q1 24
$1.0B
$953.0M
Net Profit
CRL
CRL
XRAY
XRAY
Q4 25
$-276.6M
$-146.0M
Q3 25
$54.4M
$-427.0M
Q2 25
$52.3M
$-45.0M
Q1 25
$25.5M
$20.0M
Q4 24
$-214.5M
$-430.0M
Q3 24
$69.7M
$-494.0M
Q2 24
$94.1M
$-4.0M
Q1 24
$73.0M
$18.0M
Gross Margin
CRL
CRL
XRAY
XRAY
Q4 25
46.1%
Q3 25
48.8%
Q2 25
52.4%
Q1 25
53.0%
Q4 24
49.3%
Q3 24
34.6%
52.1%
Q2 24
34.5%
51.9%
Q1 24
34.1%
53.1%
Operating Margin
CRL
CRL
XRAY
XRAY
Q4 25
-28.5%
-14.5%
Q3 25
13.3%
-24.1%
Q2 25
9.7%
-13.7%
Q1 25
7.6%
7.2%
Q4 24
-16.7%
-56.2%
Q3 24
11.6%
-48.6%
Q2 24
14.8%
5.1%
Q1 24
12.5%
4.4%
Net Margin
CRL
CRL
XRAY
XRAY
Q4 25
-27.8%
-15.2%
Q3 25
5.4%
-47.2%
Q2 25
5.1%
-4.8%
Q1 25
2.6%
2.3%
Q4 24
-21.4%
-47.5%
Q3 24
6.9%
-51.9%
Q2 24
9.2%
-0.4%
Q1 24
7.2%
1.9%
EPS (diluted)
CRL
CRL
XRAY
XRAY
Q4 25
$-5.57
$-0.74
Q3 25
$1.10
$-2.14
Q2 25
$1.06
$-0.22
Q1 25
$0.50
$0.10
Q4 24
$-4.17
$-2.09
Q3 24
$1.33
$-2.46
Q2 24
$1.74
$-0.02
Q1 24
$1.30
$0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRL
CRL
XRAY
XRAY
Cash + ST InvestmentsLiquidity on hand
$213.8M
$326.0M
Total DebtLower is stronger
$2.1B
$2.3B
Stockholders' EquityBook value
$3.2B
$1.3B
Total Assets
$7.1B
$5.4B
Debt / EquityLower = less leverage
0.68×
1.70×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRL
CRL
XRAY
XRAY
Q4 25
$213.8M
$326.0M
Q3 25
$207.1M
$363.0M
Q2 25
$182.8M
$359.0M
Q1 25
$229.4M
$398.0M
Q4 24
$194.6M
$272.0M
Q3 24
$210.2M
$296.0M
Q2 24
$179.2M
$279.0M
Q1 24
$327.0M
$291.0M
Total Debt
CRL
CRL
XRAY
XRAY
Q4 25
$2.1B
$2.3B
Q3 25
$2.2B
Q2 25
$2.3B
Q1 25
$2.5B
Q4 24
$2.2B
$1.7B
Q3 24
$2.3B
Q2 24
$2.4B
Q1 24
$2.7B
Stockholders' Equity
CRL
CRL
XRAY
XRAY
Q4 25
$3.2B
$1.3B
Q3 25
$3.4B
$1.5B
Q2 25
$3.4B
$2.0B
Q1 25
$3.2B
$2.0B
Q4 24
$3.5B
$1.9B
Q3 24
$3.8B
$2.5B
Q2 24
$3.7B
$3.1B
Q1 24
$3.6B
$3.3B
Total Assets
CRL
CRL
XRAY
XRAY
Q4 25
$7.1B
$5.4B
Q3 25
$7.5B
$5.7B
Q2 25
$7.6B
$6.1B
Q1 25
$7.6B
$6.0B
Q4 24
$7.5B
$5.8B
Q3 24
$8.0B
$6.6B
Q2 24
$7.9B
$6.9B
Q1 24
$8.2B
$7.1B
Debt / Equity
CRL
CRL
XRAY
XRAY
Q4 25
0.68×
1.70×
Q3 25
0.64×
Q2 25
0.70×
Q1 25
0.79×
Q4 24
0.65×
0.90×
Q3 24
0.62×
Q2 24
0.65×
Q1 24
0.73×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRL
CRL
XRAY
XRAY
Operating Cash FlowLast quarter
$147.5M
$101.0M
Free Cash FlowOCF − Capex
$58.6M
$60.0M
FCF MarginFCF / Revenue
5.9%
6.2%
Capex IntensityCapex / Revenue
8.9%
4.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$518.5M
$104.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRL
CRL
XRAY
XRAY
Q4 25
$147.5M
$101.0M
Q3 25
$213.8M
$79.0M
Q2 25
$204.6M
$48.0M
Q1 25
$171.7M
$7.0M
Q4 24
$159.4M
$87.0M
Q3 24
$251.8M
$141.0M
Q2 24
$193.5M
$208.0M
Q1 24
$129.9M
$25.0M
Free Cash Flow
CRL
CRL
XRAY
XRAY
Q4 25
$58.6M
$60.0M
Q3 25
$178.2M
$40.0M
Q2 25
$169.3M
$16.0M
Q1 25
$112.4M
$-12.0M
Q4 24
$83.7M
$36.0M
Q3 24
$213.1M
$98.0M
Q2 24
$154.0M
$156.0M
Q1 24
$50.7M
$-9.0M
FCF Margin
CRL
CRL
XRAY
XRAY
Q4 25
5.9%
6.2%
Q3 25
17.7%
4.4%
Q2 25
16.4%
1.7%
Q1 25
11.4%
-1.4%
Q4 24
8.4%
4.0%
Q3 24
21.1%
10.3%
Q2 24
15.0%
15.9%
Q1 24
5.0%
-0.9%
Capex Intensity
CRL
CRL
XRAY
XRAY
Q4 25
8.9%
4.3%
Q3 25
3.5%
4.3%
Q2 25
3.4%
3.4%
Q1 25
6.0%
2.2%
Q4 24
7.5%
5.6%
Q3 24
3.8%
4.5%
Q2 24
3.8%
5.3%
Q1 24
7.8%
3.6%
Cash Conversion
CRL
CRL
XRAY
XRAY
Q4 25
Q3 25
3.93×
Q2 25
3.91×
Q1 25
6.74×
0.35×
Q4 24
Q3 24
3.61×
Q2 24
2.06×
Q1 24
1.78×
1.39×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRL
CRL

Discovery And Safety Assessment Segment$591.6M60%
Manufacturing Support Segment$196.4M20%
Transferred At Point In Time$108.0M11%
Transferred Over Time$98.3M10%

XRAY
XRAY

Essential Dental Solutions$372.0M39%
Equipment And Instruments$160.0M17%
Implants And Prosthetics$150.0M16%
CADCAM$139.0M14%
Wellspect Healthcare$88.0M9%
Orthodontics$52.0M5%

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