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Side-by-side financial comparison of CRISPR Therapeutics AG (CRSP) and Gloo Holdings, Inc. (GLOO). Click either name above to swap in a different company.

CRISPR Therapeutics AG is the larger business by last-quarter revenue ($35.7M vs $32.6M, roughly 1.1× Gloo Holdings, Inc.). CRISPR Therapeutics AG runs the higher net margin — -104.5% vs -116.9%, a 12.3% gap on every dollar of revenue. CRISPR Therapeutics AG produced more free cash flow last quarter ($-50.3M vs $-63.4M).

CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and common diseases. The company has approximately 500 employees and has offices in Zug, Switzerland, Boston, Massachusetts, San Francisco, California and London, United Kingdom. I...

CRSP vs GLOO — Head-to-Head

Bigger by revenue
CRSP
CRSP
1.1× larger
CRSP
$35.7M
$32.6M
GLOO
Higher net margin
CRSP
CRSP
12.3% more per $
CRSP
-104.5%
-116.9%
GLOO
More free cash flow
CRSP
CRSP
$13.1M more FCF
CRSP
$-50.3M
$-63.4M
GLOO

Income Statement — Q4 FY2024 vs Q3 FY2026

Metric
CRSP
CRSP
GLOO
GLOO
Revenue
$35.7M
$32.6M
Net Profit
$-37.3M
$-38.0M
Gross Margin
Operating Margin
-181.0%
-82.0%
Net Margin
-104.5%
-116.9%
Revenue YoY
-82.3%
Net Profit YoY
-141.8%
12.2%
EPS (diluted)
$-0.41
$-6.08

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CRSP
CRSP
GLOO
GLOO
Q4 25
$32.6M
Q4 24
$35.7M
Q4 23
$201.2M
Q3 23
$0
Q2 23
$70.0M
Q1 23
$100.0M
Net Profit
CRSP
CRSP
GLOO
GLOO
Q4 25
$-38.0M
Q4 24
$-37.3M
Q4 23
$89.3M
Q3 23
$-112.2M
Q2 23
$-77.7M
Q1 23
$-53.1M
Operating Margin
CRSP
CRSP
GLOO
GLOO
Q4 25
-82.0%
Q4 24
-181.0%
Q4 23
34.6%
Q3 23
Q2 23
-136.0%
Q1 23
-64.5%
Net Margin
CRSP
CRSP
GLOO
GLOO
Q4 25
-116.9%
Q4 24
-104.5%
Q4 23
44.4%
Q3 23
Q2 23
-111.1%
Q1 23
-53.1%
EPS (diluted)
CRSP
CRSP
GLOO
GLOO
Q4 25
$-6.08
Q4 24
$-0.41
Q4 23
$1.12
Q3 23
$-1.41
Q2 23
$-0.98
Q1 23
$-0.67

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CRSP
CRSP
GLOO
GLOO
Cash + ST InvestmentsLiquidity on hand
$1.9B
$15.1M
Total DebtLower is stronger
$176.5M
Stockholders' EquityBook value
$1.9B
$-444.4M
Total Assets
$2.2B
$206.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CRSP
CRSP
GLOO
GLOO
Q4 25
$15.1M
Q4 24
$1.9B
Q4 23
$1.7B
Q3 23
$1.7B
Q2 23
$1.8B
Q1 23
$1.9B
Total Debt
CRSP
CRSP
GLOO
GLOO
Q4 25
$176.5M
Q4 24
Q4 23
Q3 23
Q2 23
Q1 23
Stockholders' Equity
CRSP
CRSP
GLOO
GLOO
Q4 25
$-444.4M
Q4 24
$1.9B
Q4 23
$1.9B
Q3 23
$1.7B
Q2 23
$1.8B
Q1 23
$1.9B
Total Assets
CRSP
CRSP
GLOO
GLOO
Q4 25
$206.7M
Q4 24
$2.2B
Q4 23
$2.2B
Q3 23
$2.1B
Q2 23
$2.2B
Q1 23
$2.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CRSP
CRSP
GLOO
GLOO
Operating Cash FlowLast quarter
$-50.0M
$-63.0M
Free Cash FlowOCF − Capex
$-50.3M
$-63.4M
FCF MarginFCF / Revenue
-140.9%
-194.8%
Capex IntensityCapex / Revenue
0.7%
1.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-325.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CRSP
CRSP
GLOO
GLOO
Q4 25
$-63.0M
Q4 24
$-50.0M
Q4 23
$-96.1M
Q3 23
$-39.9M
Q2 23
$-133.2M
Q1 23
$8.8M
Free Cash Flow
CRSP
CRSP
GLOO
GLOO
Q4 25
$-63.4M
Q4 24
$-50.3M
Q4 23
$-96.8M
Q3 23
$-42.0M
Q2 23
$-136.8M
Q1 23
$5.7M
FCF Margin
CRSP
CRSP
GLOO
GLOO
Q4 25
-194.8%
Q4 24
-140.9%
Q4 23
-48.1%
Q3 23
Q2 23
-195.4%
Q1 23
5.7%
Capex Intensity
CRSP
CRSP
GLOO
GLOO
Q4 25
1.4%
Q4 24
0.7%
Q4 23
0.4%
Q3 23
Q2 23
5.1%
Q1 23
3.1%
Cash Conversion
CRSP
CRSP
GLOO
GLOO
Q4 25
Q4 24
Q4 23
-1.08×
Q3 23
Q2 23
Q1 23

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CRSP
CRSP

Collaboration Revenue$35.0M98%
Grant$2.3M6%

GLOO
GLOO

Platform Solutions$12.7M39%
Advertising$11.1M34%
Marketplace$3.9M12%
Midwestern Acquisition$2.7M8%
Servant Acquisition$1.8M6%

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