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Side-by-side financial comparison of CASTLE BIOSCIENCES INC (CSTL) and FIRST BUSINESS FINANCIAL SERVICES, INC. (FBIZ). Click either name above to swap in a different company.

CASTLE BIOSCIENCES INC is the larger business by last-quarter revenue ($83.7M vs $44.3M, roughly 1.9× FIRST BUSINESS FINANCIAL SERVICES, INC.). FIRST BUSINESS FINANCIAL SERVICES, INC. runs the higher net margin — 27.5% vs -17.4%, a 44.9% gap on every dollar of revenue. On growth, FIRST BUSINESS FINANCIAL SERVICES, INC. posted the faster year-over-year revenue change (8.5% vs -4.9%). Over the past eight quarters, FIRST BUSINESS FINANCIAL SERVICES, INC.'s revenue compounded faster (8.0% CAGR vs -1.9%).

Castle Biosciences Inc. is a commercial-stage diagnostic firm that develops and markets proprietary, clinically actionable tests for dermatological conditions such as melanoma and other skin cancers, plus rare diseases. It operates mainly in the U.S. healthcare market, focusing on segments with high unmet need for more accurate diagnostics to guide treatment choices.

The PNC Financial Services Group, Inc. is an American bank holding company and financial services corporation based in Pittsburgh, Pennsylvania. Its banking subsidiary, PNC Bank, operates in 27 states and the District of Columbia, with 2,629 branches and 9,523 ATMs. PNC Bank is one of the largest banks in the US by assets and by number of branches, deposits, and ATMs.

CSTL vs FBIZ — Head-to-Head

Bigger by revenue
CSTL
CSTL
1.9× larger
CSTL
$83.7M
$44.3M
FBIZ
Growing faster (revenue YoY)
FBIZ
FBIZ
+13.4% gap
FBIZ
8.5%
-4.9%
CSTL
Higher net margin
FBIZ
FBIZ
44.9% more per $
FBIZ
27.5%
-17.4%
CSTL
Faster 2-yr revenue CAGR
FBIZ
FBIZ
Annualised
FBIZ
8.0%
-1.9%
CSTL

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
CSTL
CSTL
FBIZ
FBIZ
Revenue
$83.7M
$44.3M
Net Profit
$-14.5M
$12.2M
Gross Margin
Operating Margin
Net Margin
-17.4%
27.5%
Revenue YoY
-4.9%
8.5%
Net Profit YoY
43.8%
9.2%
EPS (diluted)
$-0.49
$1.44

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$83.7M
$44.3M
Q4 25
$87.0M
$42.2M
Q3 25
$83.0M
$44.5M
Q2 25
$86.2M
$41.0M
Q1 25
$88.0M
$40.8M
Q4 24
$86.3M
$41.2M
Q3 24
$85.8M
$38.1M
Q2 24
$87.0M
$38.0M
Net Profit
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$-14.5M
$12.2M
Q4 25
$13.3M
Q3 25
$-501.0K
$14.4M
Q2 25
$4.5M
$11.4M
Q1 25
$-25.8M
$11.2M
Q4 24
$14.4M
Q3 24
$2.3M
$10.5M
Q2 24
$8.9M
$10.5M
Gross Margin
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
79.0%
Q3 25
77.5%
Q2 25
79.5%
Q1 25
81.4%
Q4 24
81.3%
Q3 24
81.8%
Q2 24
83.3%
Operating Margin
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
-4.4%
38.5%
Q3 25
-8.2%
39.0%
Q2 25
-4.9%
32.6%
Q1 25
-31.7%
33.0%
Q4 24
4.7%
37.2%
Q3 24
5.9%
33.8%
Q2 24
5.8%
32.6%
Net Margin
CSTL
CSTL
FBIZ
FBIZ
Q1 26
-17.4%
27.5%
Q4 25
31.6%
Q3 25
-0.6%
32.3%
Q2 25
5.2%
27.8%
Q1 25
-29.4%
27.4%
Q4 24
35.0%
Q3 24
2.6%
27.6%
Q2 24
10.3%
27.5%
EPS (diluted)
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$-0.49
$1.44
Q4 25
$-0.06
$1.57
Q3 25
$-0.02
$1.70
Q2 25
$0.15
$1.35
Q1 25
$-0.90
$1.32
Q4 24
$0.32
$1.69
Q3 24
$0.08
$1.24
Q2 24
$0.31
$1.23

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CSTL
CSTL
FBIZ
FBIZ
Cash + ST InvestmentsLiquidity on hand
$63.8M
$265.8M
Total DebtLower is stronger
$10.1M
Stockholders' EquityBook value
$461.4M
Total Assets
$547.8M
$4.3B
Debt / EquityLower = less leverage
0.02×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$63.8M
$265.8M
Q4 25
$299.5M
$39.5M
Q3 25
$287.5M
$44.3M
Q2 25
$275.9M
$123.2M
Q1 25
$275.2M
$170.6M
Q4 24
$293.1M
$157.7M
Q3 24
$95.0M
$132.0M
Q2 24
$85.6M
$81.1M
Total Debt
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$10.1M
Q4 25
$10.1M
Q3 25
$10.0M
Q2 25
$10.0M
Q1 25
$10.0M
Q4 24
$10.0M
Q3 24
$10.0M
Q2 24
$10.0M
Stockholders' Equity
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$461.4M
Q4 25
$470.9M
$371.6M
Q3 25
$467.0M
$358.3M
Q2 25
$455.4M
$344.8M
Q1 25
$440.3M
$336.1M
Q4 24
$455.8M
$328.6M
Q3 24
$441.1M
$312.0M
Q2 24
$423.9M
$305.2M
Total Assets
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$547.8M
$4.3B
Q4 25
$578.6M
$4.1B
Q3 25
$562.8M
$4.0B
Q2 25
$544.7M
$4.0B
Q1 25
$501.7M
$3.9B
Q4 24
$531.2M
$3.9B
Q3 24
$514.6M
$3.7B
Q2 24
$487.3M
$3.9B
Debt / Equity
CSTL
CSTL
FBIZ
FBIZ
Q1 26
0.02×
Q4 25
0.02×
Q3 25
0.02×
Q2 25
0.02×
Q1 25
0.02×
Q4 24
0.02×
Q3 24
0.02×
Q2 24
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CSTL
CSTL
FBIZ
FBIZ
Operating Cash FlowLast quarter
$-22.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CSTL
CSTL
FBIZ
FBIZ
Q1 26
$-22.1M
Q4 25
$26.9M
$61.7M
Q3 25
$22.6M
$18.4M
Q2 25
$20.8M
$15.8M
Q1 25
$-6.0M
$11.3M
Q4 24
$24.4M
$57.5M
Q3 24
$23.3M
$13.8M
Q2 24
$24.0M
$13.1M
Free Cash Flow
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
$19.7M
$61.1M
Q3 25
$7.8M
$18.3M
Q2 25
$11.6M
$15.5M
Q1 25
$-10.8M
$11.2M
Q4 24
$16.8M
$57.3M
Q3 24
$17.0M
$13.2M
Q2 24
$18.8M
$12.7M
FCF Margin
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
22.7%
144.7%
Q3 25
9.4%
41.0%
Q2 25
13.4%
37.8%
Q1 25
-12.2%
27.5%
Q4 24
19.5%
139.2%
Q3 24
19.8%
34.6%
Q2 24
21.6%
33.3%
Capex Intensity
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
8.3%
1.4%
Q3 25
17.9%
0.3%
Q2 25
10.7%
0.8%
Q1 25
5.4%
0.2%
Q4 24
8.8%
0.5%
Q3 24
7.4%
1.6%
Q2 24
6.0%
1.1%
Cash Conversion
CSTL
CSTL
FBIZ
FBIZ
Q1 26
Q4 25
4.63×
Q3 25
1.28×
Q2 25
4.60×
1.39×
Q1 25
1.01×
Q4 24
3.99×
Q3 24
10.29×
1.31×
Q2 24
2.69×
1.25×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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