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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and CuriosityStream Inc. (CURI). Click either name above to swap in a different company.

CuriosityStream Inc. is the larger business by last-quarter revenue ($19.2M vs $18.7M, roughly 1.0× CytomX Therapeutics, Inc.). CytomX Therapeutics, Inc. runs the higher net margin — -0.8% vs -19.7%, a 18.9% gap on every dollar of revenue. On growth, CuriosityStream Inc. posted the faster year-over-year revenue change (35.8% vs -25.7%). CuriosityStream Inc. produced more free cash flow last quarter ($3.9M vs $-15.8M). Over the past eight quarters, CuriosityStream Inc.'s revenue compounded faster (26.5% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

Curiosity Stream Inc., formerly branded as CuriosityStream, is an American media company and over-the-top subscription video streaming service which offers documentary programming including films, series, and TV shows. The company offers a video on demand subscription service branded as "Curiosity Stream" and a linear broadcast television channel known as the Curiosity Channel through various services including FuboTV and The Roku Channel.

CTMX vs CURI — Head-to-Head

Bigger by revenue
CURI
CURI
1.0× larger
CURI
$19.2M
$18.7M
CTMX
Growing faster (revenue YoY)
CURI
CURI
+61.5% gap
CURI
35.8%
-25.7%
CTMX
Higher net margin
CTMX
CTMX
18.9% more per $
CTMX
-0.8%
-19.7%
CURI
More free cash flow
CURI
CURI
$19.7M more FCF
CURI
$3.9M
$-15.8M
CTMX
Faster 2-yr revenue CAGR
CURI
CURI
Annualised
CURI
26.5%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
CURI
CURI
Revenue
$18.7M
$19.2M
Net Profit
$-154.0K
$-3.8M
Gross Margin
Operating Margin
-6.9%
-17.6%
Net Margin
-0.8%
-19.7%
Revenue YoY
-25.7%
35.8%
Net Profit YoY
97.6%
-34.6%
EPS (diluted)
$-0.07

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
CURI
CURI
Q4 25
$19.2M
Q3 25
$18.4M
Q2 25
$18.7M
$19.0M
Q1 25
$50.9M
$15.1M
Q4 24
$38.1M
$14.1M
Q3 24
$33.4M
$12.6M
Q2 24
$25.1M
$12.4M
Q1 24
$41.5M
$12.0M
Net Profit
CTMX
CTMX
CURI
CURI
Q4 25
$-3.8M
Q3 25
$-3.7M
Q2 25
$-154.0K
$784.0K
Q1 25
$23.5M
$319.0K
Q4 24
$18.9M
$-2.8M
Q3 24
$5.7M
$-3.1M
Q2 24
$-6.5M
$-2.0M
Q1 24
$13.8M
$-5.0M
Operating Margin
CTMX
CTMX
CURI
CURI
Q4 25
-17.6%
Q3 25
-24.5%
Q2 25
-6.9%
2.5%
Q1 25
44.4%
0.5%
Q4 24
46.4%
-27.4%
Q3 24
12.3%
-25.8%
Q2 24
-33.7%
-20.6%
Q1 24
28.1%
-30.4%
Net Margin
CTMX
CTMX
CURI
CURI
Q4 25
-19.7%
Q3 25
-20.4%
Q2 25
-0.8%
4.1%
Q1 25
46.2%
2.1%
Q4 24
49.6%
-19.9%
Q3 24
17.2%
-24.3%
Q2 24
-26.0%
-16.4%
Q1 24
33.3%
-42.0%
EPS (diluted)
CTMX
CTMX
CURI
CURI
Q4 25
$-0.07
Q3 25
$-0.06
Q2 25
$0.01
Q1 25
$0.01
Q4 24
$-0.05
Q3 24
$-0.06
Q2 24
$-0.04
Q1 24
$-0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
CURI
CURI
Cash + ST InvestmentsLiquidity on hand
$49.0M
$27.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$119.9M
$41.5M
Total Assets
$175.1M
$75.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
CURI
CURI
Q4 25
$27.3M
Q3 25
$27.8M
Q2 25
$49.0M
$28.1M
Q1 25
$47.6M
$33.4M
Q4 24
$38.1M
$32.1M
Q3 24
$40.6M
$33.2M
Q2 24
$43.2M
$39.5M
Q1 24
$36.2M
$38.8M
Stockholders' Equity
CTMX
CTMX
CURI
CURI
Q4 25
$41.5M
Q3 25
$47.2M
Q2 25
$119.9M
$49.8M
Q1 25
$25.0M
$58.1M
Q4 24
$-456.0K
$57.8M
Q3 24
$-23.5M
$62.2M
Q2 24
$-31.2M
$64.8M
Q1 24
$-31.7M
$67.0M
Total Assets
CTMX
CTMX
CURI
CURI
Q4 25
$75.7M
Q3 25
$74.7M
Q2 25
$175.1M
$78.7M
Q1 25
$98.5M
$85.3M
Q4 24
$120.5M
$86.2M
Q3 24
$139.0M
$87.6M
Q2 24
$159.2M
$90.9M
Q1 24
$184.7M
$94.6M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
CURI
CURI
Operating Cash FlowLast quarter
$-15.8M
$4.0M
Free Cash FlowOCF − Capex
$-15.8M
$3.9M
FCF MarginFCF / Revenue
-84.6%
20.5%
Capex IntensityCapex / Revenue
0.1%
0.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
CURI
CURI
Q4 25
$4.0M
Q3 25
$4.4M
Q2 25
$-15.8M
$2.8M
Q1 25
$-21.0M
$1.9M
Q4 24
$-19.9M
$3.0M
Q3 24
$-20.7M
$2.3M
Q2 24
$-19.5M
$2.2M
Q1 24
$-26.0M
$666.0K
Free Cash Flow
CTMX
CTMX
CURI
CURI
Q4 25
$3.9M
Q3 25
Q2 25
$-15.8M
Q1 25
$-21.2M
$1.8M
Q4 24
$-20.0M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
FCF Margin
CTMX
CTMX
CURI
CURI
Q4 25
20.5%
Q3 25
Q2 25
-84.6%
Q1 25
-41.6%
12.2%
Q4 24
-52.5%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Capex Intensity
CTMX
CTMX
CURI
CURI
Q4 25
0.1%
Q3 25
0.0%
Q2 25
0.1%
0.0%
Q1 25
0.2%
0.5%
Q4 24
0.2%
0.0%
Q3 24
0.1%
0.0%
Q2 24
0.4%
0.0%
Q1 24
0.3%
0.0%
Cash Conversion
CTMX
CTMX
CURI
CURI
Q4 25
Q3 25
Q2 25
3.56×
Q1 25
-0.89×
6.03×
Q4 24
-1.05×
Q3 24
-3.61×
Q2 24
Q1 24
-1.89×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

CURI
CURI

Segment breakdown not available.

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