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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and Crexendo, Inc. (CXDO). Click either name above to swap in a different company.

CytomX Therapeutics, Inc. is the larger business by last-quarter revenue ($18.7M vs $18.1M, roughly 1.0× Crexendo, Inc.). Crexendo, Inc. runs the higher net margin — 6.7% vs -0.8%, a 7.6% gap on every dollar of revenue. On growth, Crexendo, Inc. posted the faster year-over-year revenue change (11.2% vs -25.7%). Over the past eight quarters, Crexendo, Inc.'s revenue compounded faster (12.4% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

Crexendo, Inc. is a U.S.-headquartered cloud communications technology provider. It delivers unified communications as a service (UCaaS), contact center solutions, business VoIP services, and collaborative work tools, primarily catering to small and medium-sized enterprises operating in the North American market.

CTMX vs CXDO — Head-to-Head

Bigger by revenue
CTMX
CTMX
1.0× larger
CTMX
$18.7M
$18.1M
CXDO
Growing faster (revenue YoY)
CXDO
CXDO
+36.9% gap
CXDO
11.2%
-25.7%
CTMX
Higher net margin
CXDO
CXDO
7.6% more per $
CXDO
6.7%
-0.8%
CTMX
Faster 2-yr revenue CAGR
CXDO
CXDO
Annualised
CXDO
12.4%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
CXDO
CXDO
Revenue
$18.7M
$18.1M
Net Profit
$-154.0K
$1.2M
Gross Margin
Operating Margin
-6.9%
6.3%
Net Margin
-0.8%
6.7%
Revenue YoY
-25.7%
11.2%
Net Profit YoY
97.6%
140.2%
EPS (diluted)
$0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
CXDO
CXDO
Q4 25
$18.1M
Q3 25
$17.5M
Q2 25
$18.7M
$16.6M
Q1 25
$50.9M
$16.1M
Q4 24
$38.1M
$16.2M
Q3 24
$33.4M
$15.6M
Q2 24
$25.1M
$14.7M
Q1 24
$41.5M
$14.3M
Net Profit
CTMX
CTMX
CXDO
CXDO
Q4 25
$1.2M
Q3 25
$1.4M
Q2 25
$-154.0K
$1.2M
Q1 25
$23.5M
$1.2M
Q4 24
$18.9M
$507.0K
Q3 24
$5.7M
$148.0K
Q2 24
$-6.5M
$588.0K
Q1 24
$13.8M
$434.0K
Operating Margin
CTMX
CTMX
CXDO
CXDO
Q4 25
6.3%
Q3 25
7.5%
Q2 25
-6.9%
6.7%
Q1 25
44.4%
7.2%
Q4 24
46.4%
3.9%
Q3 24
12.3%
0.9%
Q2 24
-33.7%
3.9%
Q1 24
28.1%
3.4%
Net Margin
CTMX
CTMX
CXDO
CXDO
Q4 25
6.7%
Q3 25
8.3%
Q2 25
-0.8%
7.4%
Q1 25
46.2%
7.3%
Q4 24
49.6%
3.1%
Q3 24
17.2%
0.9%
Q2 24
-26.0%
4.0%
Q1 24
33.3%
3.0%
EPS (diluted)
CTMX
CTMX
CXDO
CXDO
Q4 25
$0.03
Q3 25
$0.05
Q2 25
$0.04
Q1 25
$0.04
Q4 24
$0.03
Q3 24
$0.00
Q2 24
$0.02
Q1 24
$0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
CXDO
CXDO
Cash + ST InvestmentsLiquidity on hand
$49.0M
Total DebtLower is stronger
$114.0K
Stockholders' EquityBook value
$119.9M
$63.8M
Total Assets
$175.1M
$77.7M
Debt / EquityLower = less leverage
0.00×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
CXDO
CXDO
Q4 25
Q3 25
Q2 25
$49.0M
Q1 25
$47.6M
Q4 24
$38.1M
Q3 24
$40.6M
Q2 24
$43.2M
Q1 24
$36.2M
Total Debt
CTMX
CTMX
CXDO
CXDO
Q4 25
$114.0K
Q3 25
$236.0K
Q2 25
$356.0K
Q1 25
$475.0K
Q4 24
$592.0K
Q3 24
$709.0K
Q2 24
$823.0K
Q1 24
$937.0K
Stockholders' Equity
CTMX
CTMX
CXDO
CXDO
Q4 25
$63.8M
Q3 25
$61.3M
Q2 25
$119.9M
$58.3M
Q1 25
$25.0M
$55.2M
Q4 24
$-456.0K
$51.4M
Q3 24
$-23.5M
$49.5M
Q2 24
$-31.2M
$48.2M
Q1 24
$-31.7M
$46.8M
Total Assets
CTMX
CTMX
CXDO
CXDO
Q4 25
$77.7M
Q3 25
$76.0M
Q2 25
$175.1M
$71.4M
Q1 25
$98.5M
$67.4M
Q4 24
$120.5M
$64.9M
Q3 24
$139.0M
$62.3M
Q2 24
$159.2M
$59.6M
Q1 24
$184.7M
$57.5M
Debt / Equity
CTMX
CTMX
CXDO
CXDO
Q4 25
0.00×
Q3 25
0.00×
Q2 25
0.01×
Q1 25
0.01×
Q4 24
0.01×
Q3 24
0.01×
Q2 24
0.02×
Q1 24
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
CXDO
CXDO
Operating Cash FlowLast quarter
$-15.8M
$2.3M
Free Cash FlowOCF − Capex
$-15.8M
FCF MarginFCF / Revenue
-84.6%
Capex IntensityCapex / Revenue
0.1%
0.0%
Cash ConversionOCF / Net Profit
1.93×
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
CXDO
CXDO
Q4 25
$2.3M
Q3 25
$4.4M
Q2 25
$-15.8M
$1.3M
Q1 25
$-21.0M
$1.2M
Q4 24
$-19.9M
$2.2M
Q3 24
$-20.7M
$1.6M
Q2 24
$-19.5M
$2.7M
Q1 24
$-26.0M
$-166.0K
Free Cash Flow
CTMX
CTMX
CXDO
CXDO
Q4 25
Q3 25
Q2 25
$-15.8M
$1.3M
Q1 25
$-21.2M
Q4 24
$-20.0M
$2.1M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
FCF Margin
CTMX
CTMX
CXDO
CXDO
Q4 25
Q3 25
Q2 25
-84.6%
7.7%
Q1 25
-41.6%
Q4 24
-52.5%
13.2%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Capex Intensity
CTMX
CTMX
CXDO
CXDO
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.1%
0.1%
Q1 25
0.2%
0.0%
Q4 24
0.2%
0.2%
Q3 24
0.1%
0.0%
Q2 24
0.4%
0.0%
Q1 24
0.3%
0.0%
Cash Conversion
CTMX
CTMX
CXDO
CXDO
Q4 25
1.93×
Q3 25
3.05×
Q2 25
1.05×
Q1 25
-0.89×
1.06×
Q4 24
-1.05×
4.29×
Q3 24
-3.61×
10.95×
Q2 24
4.51×
Q1 24
-1.89×
-0.38×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

CXDO
CXDO

Services$8.6M48%
Software Solution Segment$8.3M46%
Products$1.1M6%

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