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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and ECB Bancorp, Inc. (ECBK). Click either name above to swap in a different company.

CytomX Therapeutics, Inc. is the larger business by last-quarter revenue ($18.7M vs $9.5M, roughly 2.0× ECB Bancorp, Inc.). ECB Bancorp, Inc. runs the higher net margin — 27.3% vs -0.8%, a 28.1% gap on every dollar of revenue. On growth, ECB Bancorp, Inc. posted the faster year-over-year revenue change (33.8% vs -25.7%). ECB Bancorp, Inc. produced more free cash flow last quarter ($9.0M vs $-15.8M). Over the past eight quarters, ECB Bancorp, Inc.'s revenue compounded faster (23.8% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

ECB Bancorp, Inc. (MD) is a US-based bank holding company. It offers a full suite of retail and commercial banking products including deposit accounts, consumer loans, commercial financing and wealth management solutions, primarily serving individuals and small-to-mid enterprises across local markets in Maryland.

CTMX vs ECBK — Head-to-Head

Bigger by revenue
CTMX
CTMX
2.0× larger
CTMX
$18.7M
$9.5M
ECBK
Growing faster (revenue YoY)
ECBK
ECBK
+59.5% gap
ECBK
33.8%
-25.7%
CTMX
Higher net margin
ECBK
ECBK
28.1% more per $
ECBK
27.3%
-0.8%
CTMX
More free cash flow
ECBK
ECBK
$24.8M more FCF
ECBK
$9.0M
$-15.8M
CTMX
Faster 2-yr revenue CAGR
ECBK
ECBK
Annualised
ECBK
23.8%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
ECBK
ECBK
Revenue
$18.7M
$9.5M
Net Profit
$-154.0K
$2.6M
Gross Margin
Operating Margin
-6.9%
36.7%
Net Margin
-0.8%
27.3%
Revenue YoY
-25.7%
33.8%
Net Profit YoY
97.6%
79.5%
EPS (diluted)
$0.32

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
ECBK
ECBK
Q4 25
$9.5M
Q3 25
$8.8M
Q2 25
$18.7M
$8.0M
Q1 25
$50.9M
$6.9M
Q4 24
$38.1M
$7.1M
Q3 24
$33.4M
$6.6M
Q2 24
$25.1M
$6.3M
Q1 24
$41.5M
$6.2M
Net Profit
CTMX
CTMX
ECBK
ECBK
Q4 25
$2.6M
Q3 25
$2.4M
Q2 25
$-154.0K
$1.4M
Q1 25
$23.5M
$1.3M
Q4 24
$18.9M
$1.4M
Q3 24
$5.7M
$1.1M
Q2 24
$-6.5M
$791.0K
Q1 24
$13.8M
$621.0K
Operating Margin
CTMX
CTMX
ECBK
ECBK
Q4 25
36.7%
Q3 25
37.0%
Q2 25
-6.9%
23.9%
Q1 25
44.4%
24.9%
Q4 24
46.4%
27.3%
Q3 24
12.3%
23.3%
Q2 24
-33.7%
16.9%
Q1 24
28.1%
13.4%
Net Margin
CTMX
CTMX
ECBK
ECBK
Q4 25
27.3%
Q3 25
27.7%
Q2 25
-0.8%
18.0%
Q1 25
46.2%
18.7%
Q4 24
49.6%
20.3%
Q3 24
17.2%
17.2%
Q2 24
-26.0%
12.6%
Q1 24
33.3%
10.0%
EPS (diluted)
CTMX
CTMX
ECBK
ECBK
Q4 25
$0.32
Q3 25
$0.29
Q2 25
$0.17
Q1 25
$0.16
Q4 24
$0.18
Q3 24
$0.14
Q2 24
$0.09
Q1 24
$0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
ECBK
ECBK
Cash + ST InvestmentsLiquidity on hand
$49.0M
$82.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$119.9M
$171.9M
Total Assets
$175.1M
$1.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
ECBK
ECBK
Q4 25
$82.8M
Q3 25
$201.9M
Q2 25
$49.0M
$191.0M
Q1 25
$47.6M
$143.7M
Q4 24
$38.1M
$309.4M
Q3 24
$40.6M
$114.8M
Q2 24
$43.2M
$108.7M
Q1 24
$36.2M
$109.8M
Stockholders' Equity
CTMX
CTMX
ECBK
ECBK
Q4 25
$171.9M
Q3 25
$169.3M
Q2 25
$119.9M
$168.3M
Q1 25
$25.0M
$168.6M
Q4 24
$-456.0K
$168.3M
Q3 24
$-23.5M
$166.0M
Q2 24
$-31.2M
$166.5M
Q1 24
$-31.7M
$165.8M
Total Assets
CTMX
CTMX
ECBK
ECBK
Q4 25
$1.6B
Q3 25
$1.6B
Q2 25
$175.1M
$1.5B
Q1 25
$98.5M
$1.5B
Q4 24
$120.5M
$1.4B
Q3 24
$139.0M
$1.4B
Q2 24
$159.2M
$1.3B
Q1 24
$184.7M
$1.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
ECBK
ECBK
Operating Cash FlowLast quarter
$-15.8M
$9.2M
Free Cash FlowOCF − Capex
$-15.8M
$9.0M
FCF MarginFCF / Revenue
-84.6%
94.7%
Capex IntensityCapex / Revenue
0.1%
2.2%
Cash ConversionOCF / Net Profit
3.55×
TTM Free Cash FlowTrailing 4 quarters
$-77.7M
$14.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
ECBK
ECBK
Q4 25
$9.2M
Q3 25
$4.0M
Q2 25
$-15.8M
$1.9M
Q1 25
$-21.0M
$-631.0K
Q4 24
$-19.9M
$6.2M
Q3 24
$-20.7M
$861.0K
Q2 24
$-19.5M
$1.4M
Q1 24
$-26.0M
$-429.0K
Free Cash Flow
CTMX
CTMX
ECBK
ECBK
Q4 25
$9.0M
Q3 25
$4.0M
Q2 25
$-15.8M
$1.8M
Q1 25
$-21.2M
$-649.0K
Q4 24
$-20.0M
$6.2M
Q3 24
$-20.7M
Q2 24
$-19.6M
$1.3M
Q1 24
$-26.2M
$-449.0K
FCF Margin
CTMX
CTMX
ECBK
ECBK
Q4 25
94.7%
Q3 25
44.9%
Q2 25
-84.6%
23.0%
Q1 25
-41.6%
-9.4%
Q4 24
-52.5%
86.8%
Q3 24
-62.1%
Q2 24
-78.2%
21.4%
Q1 24
-63.1%
-7.2%
Capex Intensity
CTMX
CTMX
ECBK
ECBK
Q4 25
2.2%
Q3 25
0.8%
Q2 25
0.1%
0.6%
Q1 25
0.2%
0.3%
Q4 24
0.2%
0.8%
Q3 24
0.1%
0.0%
Q2 24
0.4%
0.6%
Q1 24
0.3%
0.3%
Cash Conversion
CTMX
CTMX
ECBK
ECBK
Q4 25
3.55×
Q3 25
1.65×
Q2 25
1.32×
Q1 25
-0.89×
-0.49×
Q4 24
-1.05×
4.31×
Q3 24
-3.61×
0.76×
Q2 24
1.75×
Q1 24
-1.89×
-0.69×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

ECBK
ECBK

Segment breakdown not available.

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