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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and TPG Mortgage Investment Trust, Inc. (MITT). Click either name above to swap in a different company.

TPG Mortgage Investment Trust, Inc. is the larger business by last-quarter revenue ($20.4M vs $18.7M, roughly 1.1× CytomX Therapeutics, Inc.). TPG Mortgage Investment Trust, Inc. runs the higher net margin — 65.0% vs -0.8%, a 65.8% gap on every dollar of revenue. On growth, TPG Mortgage Investment Trust, Inc. posted the faster year-over-year revenue change (17.7% vs -25.7%). Over the past eight quarters, TPG Mortgage Investment Trust, Inc.'s revenue compounded faster (9.1% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

TPG Mortgage Investment Trust, Inc. is a real estate investment trust managed by global alternative asset firm TPG. It primarily invests in residential and commercial mortgage-backed securities, performing and non-performing mortgage loans, and other credit-linked real estate assets, with its core market being the United States. It generates returns via net interest income from holdings and strategic asset disposition gains.

CTMX vs MITT — Head-to-Head

Bigger by revenue
MITT
MITT
1.1× larger
MITT
$20.4M
$18.7M
CTMX
Growing faster (revenue YoY)
MITT
MITT
+43.4% gap
MITT
17.7%
-25.7%
CTMX
Higher net margin
MITT
MITT
65.8% more per $
MITT
65.0%
-0.8%
CTMX
Faster 2-yr revenue CAGR
MITT
MITT
Annualised
MITT
9.1%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
MITT
MITT
Revenue
$18.7M
$20.4M
Net Profit
$-154.0K
$13.3M
Gross Margin
Operating Margin
-6.9%
67.1%
Net Margin
-0.8%
65.0%
Revenue YoY
-25.7%
17.7%
Net Profit YoY
97.6%
-7.0%
EPS (diluted)
$0.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
MITT
MITT
Q4 25
$20.4M
Q3 25
$19.5M
Q2 25
$18.7M
$17.8M
Q1 25
$50.9M
$18.8M
Q4 24
$38.1M
$17.4M
Q3 24
$33.4M
$14.9M
Q2 24
$25.1M
$16.4M
Q1 24
$41.5M
$17.2M
Net Profit
CTMX
CTMX
MITT
MITT
Q4 25
$13.3M
Q3 25
$20.0M
Q2 25
$-154.0K
$3.9M
Q1 25
$23.5M
$11.5M
Q4 24
$18.9M
$14.3M
Q3 24
$5.7M
$16.6M
Q2 24
$-6.5M
$3.9M
Q1 24
$13.8M
$20.9M
Operating Margin
CTMX
CTMX
MITT
MITT
Q4 25
67.1%
Q3 25
Q2 25
-6.9%
20.9%
Q1 25
44.4%
54.6%
Q4 24
46.4%
76.7%
Q3 24
12.3%
Q2 24
-33.7%
18.4%
Q1 24
28.1%
Net Margin
CTMX
CTMX
MITT
MITT
Q4 25
65.0%
Q3 25
102.5%
Q2 25
-0.8%
22.2%
Q1 25
46.2%
60.9%
Q4 24
49.6%
82.2%
Q3 24
17.2%
111.3%
Q2 24
-26.0%
24.0%
Q1 24
33.3%
121.6%
EPS (diluted)
CTMX
CTMX
MITT
MITT
Q4 25
$0.27
Q3 25
$0.47
Q2 25
$-0.05
Q1 25
$0.21
Q4 24
$0.30
Q3 24
$0.40
Q2 24
$-0.02
Q1 24
$0.55

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
MITT
MITT
Cash + ST InvestmentsLiquidity on hand
$49.0M
$57.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$119.9M
$560.7M
Total Assets
$175.1M
$8.7B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
MITT
MITT
Q4 25
$57.8M
Q3 25
$59.0M
Q2 25
$49.0M
$88.7M
Q1 25
$47.6M
$115.5M
Q4 24
$38.1M
$118.7M
Q3 24
$40.6M
$102.5M
Q2 24
$43.2M
$120.9M
Q1 24
$36.2M
$100.3M
Stockholders' Equity
CTMX
CTMX
MITT
MITT
Q4 25
$560.7M
Q3 25
$559.8M
Q2 25
$119.9M
$536.4M
Q1 25
$25.0M
$543.9M
Q4 24
$-456.0K
$543.4M
Q3 24
$-23.5M
$540.1M
Q2 24
$-31.2M
$533.5M
Q1 24
$-31.7M
$539.6M
Total Assets
CTMX
CTMX
MITT
MITT
Q4 25
$8.7B
Q3 25
$9.0B
Q2 25
$175.1M
$7.5B
Q1 25
$98.5M
$7.3B
Q4 24
$120.5M
$6.9B
Q3 24
$139.0M
$7.0B
Q2 24
$159.2M
$7.1B
Q1 24
$184.7M
$6.4B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
MITT
MITT
Operating Cash FlowLast quarter
$-15.8M
$59.6M
Free Cash FlowOCF − Capex
$-15.8M
FCF MarginFCF / Revenue
-84.6%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
4.48×
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
MITT
MITT
Q4 25
$59.6M
Q3 25
$17.4M
Q2 25
$-15.8M
$11.5M
Q1 25
$-21.0M
$12.0M
Q4 24
$-19.9M
$55.8M
Q3 24
$-20.7M
$14.5M
Q2 24
$-19.5M
$13.7M
Q1 24
$-26.0M
$12.0M
Free Cash Flow
CTMX
CTMX
MITT
MITT
Q4 25
Q3 25
Q2 25
$-15.8M
Q1 25
$-21.2M
Q4 24
$-20.0M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
FCF Margin
CTMX
CTMX
MITT
MITT
Q4 25
Q3 25
Q2 25
-84.6%
Q1 25
-41.6%
Q4 24
-52.5%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Capex Intensity
CTMX
CTMX
MITT
MITT
Q4 25
Q3 25
Q2 25
0.1%
Q1 25
0.2%
Q4 24
0.2%
Q3 24
0.1%
Q2 24
0.4%
Q1 24
0.3%
Cash Conversion
CTMX
CTMX
MITT
MITT
Q4 25
4.48×
Q3 25
0.87×
Q2 25
2.92×
Q1 25
-0.89×
1.05×
Q4 24
-1.05×
3.91×
Q3 24
-3.61×
0.87×
Q2 24
3.50×
Q1 24
-1.89×
0.57×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

MITT
MITT

Segment breakdown not available.

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