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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and MANNATECH INC (MTEX). Click either name above to swap in a different company.

MANNATECH INC is the larger business by last-quarter revenue ($29.2M vs $18.7M, roughly 1.6× CytomX Therapeutics, Inc.). MANNATECH INC runs the higher net margin — 6.6% vs -0.8%, a 7.4% gap on every dollar of revenue. On growth, MANNATECH INC posted the faster year-over-year revenue change (-8.1% vs -25.7%). MANNATECH INC produced more free cash flow last quarter ($-2.0M vs $-15.8M). Over the past eight quarters, MANNATECH INC's revenue compounded faster (-5.4% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

Mannatech Inc. is a publicly traded, multinational multi-level marketing firm that sells dietary supplements and personal care products. It was founded in November 1993 by Samuel Caster, and is headquartered in Flower Mound, Texas. The company's stock is traded on the NASDAQ exchange under the symbol MTEX. As of 2017, Mannatech employed 252 people and sold its products through some 220,000 independent sales associates.

CTMX vs MTEX — Head-to-Head

Bigger by revenue
MTEX
MTEX
1.6× larger
MTEX
$29.2M
$18.7M
CTMX
Growing faster (revenue YoY)
MTEX
MTEX
+17.6% gap
MTEX
-8.1%
-25.7%
CTMX
Higher net margin
MTEX
MTEX
7.4% more per $
MTEX
6.6%
-0.8%
CTMX
More free cash flow
MTEX
MTEX
$13.8M more FCF
MTEX
$-2.0M
$-15.8M
CTMX
Faster 2-yr revenue CAGR
MTEX
MTEX
Annualised
MTEX
-5.4%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q3 FY2025

Metric
CTMX
CTMX
MTEX
MTEX
Revenue
$18.7M
$29.2M
Net Profit
$-154.0K
$1.9M
Gross Margin
76.4%
Operating Margin
-6.9%
6.9%
Net Margin
-0.8%
6.6%
Revenue YoY
-25.7%
-8.1%
Net Profit YoY
97.6%
686.6%
EPS (diluted)
$1.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
MTEX
MTEX
Q3 25
$29.2M
Q2 25
$18.7M
Q1 25
$50.9M
$26.6M
Q4 24
$38.1M
$29.0M
Q3 24
$33.4M
$31.7M
Q2 24
$25.1M
$27.7M
Q1 24
$41.5M
$29.4M
Q4 23
$26.6M
$32.7M
Net Profit
CTMX
CTMX
MTEX
MTEX
Q3 25
$1.9M
Q2 25
$-154.0K
Q1 25
$23.5M
$-1.5M
Q4 24
$18.9M
$2.3M
Q3 24
$5.7M
$-328.0K
Q2 24
$-6.5M
$-624.0K
Q1 24
$13.8M
$1.2M
Q4 23
$837.0K
$-1.8M
Gross Margin
CTMX
CTMX
MTEX
MTEX
Q3 25
76.4%
Q2 25
Q1 25
74.3%
Q4 24
80.6%
Q3 24
74.5%
Q2 24
77.1%
Q1 24
78.6%
Q4 23
75.4%
Operating Margin
CTMX
CTMX
MTEX
MTEX
Q3 25
6.9%
Q2 25
-6.9%
Q1 25
44.4%
-3.1%
Q4 24
46.4%
3.0%
Q3 24
12.3%
2.8%
Q2 24
-33.7%
-4.1%
Q1 24
28.1%
2.8%
Q4 23
-2.3%
-2.7%
Net Margin
CTMX
CTMX
MTEX
MTEX
Q3 25
6.6%
Q2 25
-0.8%
Q1 25
46.2%
-5.8%
Q4 24
49.6%
7.8%
Q3 24
17.2%
-1.0%
Q2 24
-26.0%
-2.2%
Q1 24
33.3%
4.0%
Q4 23
3.1%
-5.4%
EPS (diluted)
CTMX
CTMX
MTEX
MTEX
Q3 25
$1.01
Q2 25
Q1 25
$-0.80
Q4 24
$1.19
Q3 24
$-0.17
Q2 24
$-0.33
Q1 24
$0.63
Q4 23
$-0.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
MTEX
MTEX
Cash + ST InvestmentsLiquidity on hand
$49.0M
$7.1M
Total DebtLower is stronger
$2.9M
Stockholders' EquityBook value
$119.9M
$7.0M
Total Assets
$175.1M
$33.9M
Debt / EquityLower = less leverage
0.42×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
MTEX
MTEX
Q3 25
$7.1M
Q2 25
$49.0M
Q1 25
$47.6M
$9.3M
Q4 24
$38.1M
$11.4M
Q3 24
$40.6M
$12.2M
Q2 24
$43.2M
$9.2M
Q1 24
$36.2M
$7.9M
Q4 23
$17.2M
$7.7M
Total Debt
CTMX
CTMX
MTEX
MTEX
Q3 25
$2.9M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23
Stockholders' Equity
CTMX
CTMX
MTEX
MTEX
Q3 25
$7.0M
Q2 25
$119.9M
Q1 25
$25.0M
$7.6M
Q4 24
$-456.0K
$8.6M
Q3 24
$-23.5M
$10.0M
Q2 24
$-31.2M
$8.2M
Q1 24
$-31.7M
$10.4M
Q4 23
$-47.4M
$10.5M
Total Assets
CTMX
CTMX
MTEX
MTEX
Q3 25
$33.9M
Q2 25
$175.1M
Q1 25
$98.5M
$36.7M
Q4 24
$120.5M
$36.1M
Q3 24
$139.0M
$40.6M
Q2 24
$159.2M
$39.9M
Q1 24
$184.7M
$41.1M
Q4 23
$201.8M
$41.2M
Debt / Equity
CTMX
CTMX
MTEX
MTEX
Q3 25
0.42×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
MTEX
MTEX
Operating Cash FlowLast quarter
$-15.8M
$-1.3M
Free Cash FlowOCF − Capex
$-15.8M
$-2.0M
FCF MarginFCF / Revenue
-84.6%
-6.8%
Capex IntensityCapex / Revenue
0.1%
2.4%
Cash ConversionOCF / Net Profit
-0.68×
TTM Free Cash FlowTrailing 4 quarters
$-77.7M
$-1.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
MTEX
MTEX
Q3 25
$-1.3M
Q2 25
$-15.8M
Q1 25
$-21.0M
$-1.4M
Q4 24
$-19.9M
$-219.0K
Q3 24
$-20.7M
$3.3M
Q2 24
$-19.5M
$-2.7M
Q1 24
$-26.0M
$1.9M
Q4 23
$-22.0M
$-1.3M
Free Cash Flow
CTMX
CTMX
MTEX
MTEX
Q3 25
$-2.0M
Q2 25
$-15.8M
Q1 25
$-21.2M
$-1.9M
Q4 24
$-20.0M
$-325.0K
Q3 24
$-20.7M
$3.0M
Q2 24
$-19.6M
$-2.7M
Q1 24
$-26.2M
$1.8M
Q4 23
$-22.2M
$-1.5M
FCF Margin
CTMX
CTMX
MTEX
MTEX
Q3 25
-6.8%
Q2 25
-84.6%
Q1 25
-41.6%
-7.0%
Q4 24
-52.5%
-1.1%
Q3 24
-62.1%
9.5%
Q2 24
-78.2%
-9.9%
Q1 24
-63.1%
6.2%
Q4 23
-83.5%
-4.7%
Capex Intensity
CTMX
CTMX
MTEX
MTEX
Q3 25
2.4%
Q2 25
0.1%
Q1 25
0.2%
1.8%
Q4 24
0.2%
0.4%
Q3 24
0.1%
0.8%
Q2 24
0.4%
0.3%
Q1 24
0.3%
0.2%
Q4 23
1.0%
0.6%
Cash Conversion
CTMX
CTMX
MTEX
MTEX
Q3 25
-0.68×
Q2 25
Q1 25
-0.89×
Q4 24
-1.05×
-0.10×
Q3 24
-3.61×
Q2 24
Q1 24
-1.89×
1.59×
Q4 23
-26.24×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

MTEX
MTEX

Segment breakdown not available.

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