vs

Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and Seaport Entertainment Group Inc. (SEG). Click either name above to swap in a different company.

Seaport Entertainment Group Inc. is the larger business by last-quarter revenue ($29.5M vs $18.7M, roughly 1.6× CytomX Therapeutics, Inc.). CytomX Therapeutics, Inc. runs the higher net margin — -0.8% vs -125.0%, a 124.2% gap on every dollar of revenue.

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

CTMX vs SEG — Head-to-Head

Bigger by revenue
SEG
SEG
1.6× larger
SEG
$29.5M
$18.7M
CTMX
Higher net margin
CTMX
CTMX
124.2% more per $
CTMX
-0.8%
-125.0%
SEG

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
SEG
SEG
Revenue
$18.7M
$29.5M
Net Profit
$-154.0K
$-36.9M
Gross Margin
Operating Margin
-6.9%
-120.5%
Net Margin
-0.8%
-125.0%
Revenue YoY
-25.7%
Net Profit YoY
97.6%
EPS (diluted)
$-2.90

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
SEG
SEG
Q4 25
$29.5M
Q3 25
$45.0M
Q2 25
$18.7M
$39.8M
Q1 25
$50.9M
$16.1M
Q4 24
$38.1M
Q3 24
$33.4M
$39.4M
Q2 24
$25.1M
$33.7M
Q1 24
$41.5M
Net Profit
CTMX
CTMX
SEG
SEG
Q4 25
$-36.9M
Q3 25
$-33.2M
Q2 25
$-154.0K
$-14.8M
Q1 25
$23.5M
$-31.9M
Q4 24
$18.9M
Q3 24
$5.7M
$-32.5M
Q2 24
$-6.5M
$-35.0M
Q1 24
$13.8M
Operating Margin
CTMX
CTMX
SEG
SEG
Q4 25
-120.5%
Q3 25
-75.2%
Q2 25
-6.9%
-40.2%
Q1 25
44.4%
-203.5%
Q4 24
46.4%
Q3 24
12.3%
-51.0%
Q2 24
-33.7%
-75.3%
Q1 24
28.1%
Net Margin
CTMX
CTMX
SEG
SEG
Q4 25
-125.0%
Q3 25
-73.7%
Q2 25
-0.8%
-37.1%
Q1 25
46.2%
-198.4%
Q4 24
49.6%
Q3 24
17.2%
-82.5%
Q2 24
-26.0%
-103.9%
Q1 24
33.3%
EPS (diluted)
CTMX
CTMX
SEG
SEG
Q4 25
$-2.90
Q3 25
$-2.61
Q2 25
$-1.16
Q1 25
$-2.51
Q4 24
Q3 24
$-5.89
Q2 24
$-6.34
Q1 24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
SEG
SEG
Cash + ST InvestmentsLiquidity on hand
$49.0M
$77.8M
Total DebtLower is stronger
$38.3M
Stockholders' EquityBook value
$119.9M
$456.5M
Total Assets
$175.1M
$650.1M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
SEG
SEG
Q4 25
$77.8M
Q3 25
$106.2M
Q2 25
$49.0M
$123.3M
Q1 25
$47.6M
$129.9M
Q4 24
$38.1M
Q3 24
$40.6M
$23.7M
Q2 24
$43.2M
$3.3M
Q1 24
$36.2M
Total Debt
CTMX
CTMX
SEG
SEG
Q4 25
$38.3M
Q3 25
$39.3M
Q2 25
$100.6M
Q1 25
$101.6M
Q4 24
Q3 24
$103.3M
Q2 24
$157.1M
Q1 24
Stockholders' Equity
CTMX
CTMX
SEG
SEG
Q4 25
$456.5M
Q3 25
$485.8M
Q2 25
$119.9M
$517.9M
Q1 25
$25.0M
$531.2M
Q4 24
$-456.0K
Q3 24
$-23.5M
$433.8M
Q2 24
$-31.2M
$380.7M
Q1 24
$-31.7M
Total Assets
CTMX
CTMX
SEG
SEG
Q4 25
$650.1M
Q3 25
$699.1M
Q2 25
$175.1M
$717.2M
Q1 25
$98.5M
$718.4M
Q4 24
$120.5M
Q3 24
$139.0M
$622.8M
Q2 24
$159.2M
$610.1M
Q1 24
$184.7M
Debt / Equity
CTMX
CTMX
SEG
SEG
Q4 25
0.08×
Q3 25
0.08×
Q2 25
0.19×
Q1 25
0.19×
Q4 24
Q3 24
0.24×
Q2 24
0.41×
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
SEG
SEG
Operating Cash FlowLast quarter
$-15.8M
$-23.1M
Free Cash FlowOCF − Capex
$-15.8M
FCF MarginFCF / Revenue
-84.6%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
SEG
SEG
Q4 25
$-23.1M
Q3 25
$-5.3M
Q2 25
$-15.8M
$-754.0K
Q1 25
$-21.0M
$-20.5M
Q4 24
$-19.9M
Q3 24
$-20.7M
$-8.8M
Q2 24
$-19.5M
Q1 24
$-26.0M
Free Cash Flow
CTMX
CTMX
SEG
SEG
Q4 25
Q3 25
Q2 25
$-15.8M
Q1 25
$-21.2M
Q4 24
$-20.0M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
FCF Margin
CTMX
CTMX
SEG
SEG
Q4 25
Q3 25
Q2 25
-84.6%
Q1 25
-41.6%
Q4 24
-52.5%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Capex Intensity
CTMX
CTMX
SEG
SEG
Q4 25
Q3 25
Q2 25
0.1%
Q1 25
0.2%
Q4 24
0.2%
Q3 24
0.1%
Q2 24
0.4%
Q1 24
0.3%
Cash Conversion
CTMX
CTMX
SEG
SEG
Q4 25
Q3 25
Q2 25
Q1 25
-0.89×
Q4 24
-1.05×
Q3 24
-3.61×
Q2 24
Q1 24
-1.89×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

SEG
SEG

Sponsorships Events And Entertainment$12.5M43%
Hospitality$12.2M41%
Rental$4.1M14%
Other$631.0K2%

Related Comparisons