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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and TOP SHIPS INC. (TOPS). Click either name above to swap in a different company.

TOP SHIPS INC. is the larger business by last-quarter revenue ($36.6M vs $18.7M, roughly 2.0× CytomX Therapeutics, Inc.). CytomX Therapeutics, Inc. runs the higher net margin — -0.8% vs -12.2%, a 11.4% gap on every dollar of revenue.

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

Top Ships Inc. is a supply chain maritime transportation operations management company responsible for seaborne trade of raw materials. The company was founded by Evangelos J. Pistiolis on January 10, 2000 and is headquartered in Maroussi, Greece.

CTMX vs TOPS — Head-to-Head

Bigger by revenue
TOPS
TOPS
2.0× larger
TOPS
$36.6M
$18.7M
CTMX
Higher net margin
CTMX
CTMX
11.4% more per $
CTMX
-0.8%
-12.2%
TOPS

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
TOPS
TOPS
Revenue
$18.7M
$36.6M
Net Profit
$-154.0K
$-4.5M
Gross Margin
Operating Margin
-6.9%
22.0%
Net Margin
-0.8%
-12.2%
Revenue YoY
-25.7%
Net Profit YoY
97.6%
EPS (diluted)
$-0.96

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
TOPS
TOPS
Q4 25
$36.6M
Q2 25
$18.7M
Q1 25
$50.9M
Q4 24
$38.1M
Q3 24
$33.4M
Q2 24
$25.1M
Q1 24
$41.5M
Q4 23
$26.6M
Net Profit
CTMX
CTMX
TOPS
TOPS
Q4 25
$-4.5M
Q2 25
$-154.0K
Q1 25
$23.5M
Q4 24
$18.9M
Q3 24
$5.7M
Q2 24
$-6.5M
Q1 24
$13.8M
Q4 23
$837.0K
Operating Margin
CTMX
CTMX
TOPS
TOPS
Q4 25
22.0%
Q2 25
-6.9%
Q1 25
44.4%
Q4 24
46.4%
Q3 24
12.3%
Q2 24
-33.7%
Q1 24
28.1%
Q4 23
-2.3%
Net Margin
CTMX
CTMX
TOPS
TOPS
Q4 25
-12.2%
Q2 25
-0.8%
Q1 25
46.2%
Q4 24
49.6%
Q3 24
17.2%
Q2 24
-26.0%
Q1 24
33.3%
Q4 23
3.1%
EPS (diluted)
CTMX
CTMX
TOPS
TOPS
Q4 25
$-0.96
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
TOPS
TOPS
Cash + ST InvestmentsLiquidity on hand
$49.0M
$20.4M
Total DebtLower is stronger
$216.6M
Stockholders' EquityBook value
$119.9M
$89.2M
Total Assets
$175.1M
$333.6M
Debt / EquityLower = less leverage
2.43×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
TOPS
TOPS
Q4 25
$20.4M
Q2 25
$49.0M
Q1 25
$47.6M
Q4 24
$38.1M
Q3 24
$40.6M
Q2 24
$43.2M
Q1 24
$36.2M
Q4 23
$17.2M
Total Debt
CTMX
CTMX
TOPS
TOPS
Q4 25
$216.6M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23
Stockholders' Equity
CTMX
CTMX
TOPS
TOPS
Q4 25
$89.2M
Q2 25
$119.9M
Q1 25
$25.0M
Q4 24
$-456.0K
Q3 24
$-23.5M
Q2 24
$-31.2M
Q1 24
$-31.7M
Q4 23
$-47.4M
Total Assets
CTMX
CTMX
TOPS
TOPS
Q4 25
$333.6M
Q2 25
$175.1M
Q1 25
$98.5M
Q4 24
$120.5M
Q3 24
$139.0M
Q2 24
$159.2M
Q1 24
$184.7M
Q4 23
$201.8M
Debt / Equity
CTMX
CTMX
TOPS
TOPS
Q4 25
2.43×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
TOPS
TOPS
Operating Cash FlowLast quarter
$-15.8M
$26.4M
Free Cash FlowOCF − Capex
$-15.8M
FCF MarginFCF / Revenue
-84.6%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
TOPS
TOPS
Q4 25
$26.4M
Q2 25
$-15.8M
Q1 25
$-21.0M
Q4 24
$-19.9M
Q3 24
$-20.7M
Q2 24
$-19.5M
Q1 24
$-26.0M
Q4 23
$-22.0M
Free Cash Flow
CTMX
CTMX
TOPS
TOPS
Q4 25
Q2 25
$-15.8M
Q1 25
$-21.2M
Q4 24
$-20.0M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
Q4 23
$-22.2M
FCF Margin
CTMX
CTMX
TOPS
TOPS
Q4 25
Q2 25
-84.6%
Q1 25
-41.6%
Q4 24
-52.5%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Q4 23
-83.5%
Capex Intensity
CTMX
CTMX
TOPS
TOPS
Q4 25
Q2 25
0.1%
Q1 25
0.2%
Q4 24
0.2%
Q3 24
0.1%
Q2 24
0.4%
Q1 24
0.3%
Q4 23
1.0%
Cash Conversion
CTMX
CTMX
TOPS
TOPS
Q4 25
Q2 25
Q1 25
-0.89×
Q4 24
-1.05×
Q3 24
-3.61×
Q2 24
Q1 24
-1.89×
Q4 23
-26.24×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

TOPS
TOPS

Segment breakdown not available.

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