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Side-by-side financial comparison of Cue Biopharma, Inc. (CUE) and KKR Real Estate Finance Trust Inc. (KREF). Click either name above to swap in a different company.

KKR Real Estate Finance Trust Inc. is the larger business by last-quarter revenue ($25.8M vs $21.9M, roughly 1.2× Cue Biopharma, Inc.). Cue Biopharma, Inc. runs the higher net margin — 7.2% vs -101.7%, a 109.0% gap on every dollar of revenue. On growth, Cue Biopharma, Inc. posted the faster year-over-year revenue change (1292.3% vs -26.6%). Over the past eight quarters, Cue Biopharma, Inc.'s revenue compounded faster (257.5% CAGR vs -18.8%).

Cue Biopharma is a clinical-stage biotechnology company focused on developing novel targeted immunotherapies for cancer, autoimmune disorders, and inflammatory diseases. Its proprietary platform enables precise T-cell activity modulation, with core operations in North America and global pharma partnerships to advance lead product candidates through clinical trials.

KKR Real Estate Finance Trust Inc. is a specialized real estate finance firm sponsored by global investment firm KKR. It primarily originates, acquires, and manages a portfolio of senior secured commercial real estate loans, mostly backed by high-quality institutional commercial properties across the United States, delivering stable risk-adjusted returns to investors via interest income from its diversified assets.

CUE vs KREF — Head-to-Head

Bigger by revenue
KREF
KREF
1.2× larger
KREF
$25.8M
$21.9M
CUE
Growing faster (revenue YoY)
CUE
CUE
+1318.8% gap
CUE
1292.3%
-26.6%
KREF
Higher net margin
CUE
CUE
109.0% more per $
CUE
7.2%
-101.7%
KREF
Faster 2-yr revenue CAGR
CUE
CUE
Annualised
CUE
257.5%
-18.8%
KREF

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CUE
CUE
KREF
KREF
Revenue
$21.9M
$25.8M
Net Profit
$1.6M
$-26.2M
Gross Margin
Operating Margin
9.0%
-105.1%
Net Margin
7.2%
-101.7%
Revenue YoY
1292.3%
-26.6%
Net Profit YoY
116.7%
-229.6%
EPS (diluted)
$0.05
$-0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CUE
CUE
KREF
KREF
Q4 25
$21.9M
$25.8M
Q3 25
$2.1M
$25.3M
Q2 25
$3.0M
$30.2M
Q1 25
$421.0K
$31.3M
Q4 24
$1.6M
$35.1M
Q3 24
$3.3M
$37.0M
Q2 24
$2.7M
$40.4M
Q1 24
$1.7M
$39.1M
Net Profit
CUE
CUE
KREF
KREF
Q4 25
$1.6M
$-26.2M
Q3 25
$-7.4M
$13.8M
Q2 25
$-8.5M
$-29.7M
Q1 25
$-12.3M
$-4.9M
Q4 24
$20.3M
Q3 24
$-8.7M
$-7.4M
Q2 24
$-10.2M
$25.8M
Q1 24
$-12.3M
$-3.1M
Operating Margin
CUE
CUE
KREF
KREF
Q4 25
9.0%
-105.1%
Q3 25
-353.4%
50.4%
Q2 25
-292.3%
-101.3%
Q1 25
-2921.4%
-18.3%
Q4 24
55.8%
Q3 24
-264.2%
-19.6%
Q2 24
-390.6%
63.3%
Q1 24
-737.8%
-8.7%
Net Margin
CUE
CUE
KREF
KREF
Q4 25
7.2%
-101.7%
Q3 25
-346.6%
54.4%
Q2 25
-287.1%
-98.5%
Q1 25
-2911.4%
-15.5%
Q4 24
57.7%
Q3 24
-259.6%
-20.0%
Q2 24
-382.7%
63.9%
Q1 24
-719.1%
-7.9%
EPS (diluted)
CUE
CUE
KREF
KREF
Q4 25
$0.05
$-0.49
Q3 25
$-0.07
$0.12
Q2 25
$-0.09
$-0.53
Q1 25
$-0.17
$-0.15
Q4 24
$0.22
Q3 24
$-0.17
$-0.19
Q2 24
$-0.20
$0.29
Q1 24
$-0.25
$-0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CUE
CUE
KREF
KREF
Cash + ST InvestmentsLiquidity on hand
$27.1M
$84.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$26.4M
$1.2B
Total Assets
$42.2M
$6.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CUE
CUE
KREF
KREF
Q4 25
$27.1M
$84.6M
Q3 25
$11.7M
$204.1M
Q2 25
$27.5M
$107.7M
Q1 25
$13.1M
$106.4M
Q4 24
$22.5M
$104.9M
Q3 24
$32.4M
$108.8M
Q2 24
$30.0M
$107.2M
Q1 24
$41.0M
$106.5M
Total Debt
CUE
CUE
KREF
KREF
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
$1.0M
Q2 24
$2.0M
Q1 24
$3.0M
Stockholders' Equity
CUE
CUE
KREF
KREF
Q4 25
$26.4M
$1.2B
Q3 25
$13.2M
$1.2B
Q2 25
$18.2M
$1.2B
Q1 25
$6.6M
$1.3B
Q4 24
$17.5M
$1.3B
Q3 24
$25.4M
$1.4B
Q2 24
$21.6M
$1.4B
Q1 24
$30.0M
$1.4B
Total Assets
CUE
CUE
KREF
KREF
Q4 25
$42.2M
$6.5B
Q3 25
$31.6M
$6.5B
Q2 25
$40.7M
$6.8B
Q1 25
$22.3M
$6.6B
Q4 24
$32.2M
$6.4B
Q3 24
$44.8M
$6.8B
Q2 24
$42.3M
$7.1B
Q1 24
$54.0M
$7.3B
Debt / Equity
CUE
CUE
KREF
KREF
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
0.04×
Q2 24
0.09×
Q1 24
0.10×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CUE
CUE
KREF
KREF
Operating Cash FlowLast quarter
$-1.1M
$72.3M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
-0.68×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CUE
CUE
KREF
KREF
Q4 25
$-1.1M
$72.3M
Q3 25
$-9.0M
$18.5M
Q2 25
$-3.4M
$21.1M
Q1 25
$-8.2M
$15.9M
Q4 24
$-36.3M
$132.6M
Q3 24
$-7.5M
$49.1M
Q2 24
$-10.0M
$30.6M
Q1 24
$-9.8M
$34.5M
Free Cash Flow
CUE
CUE
KREF
KREF
Q4 25
Q3 25
Q2 25
$-3.4M
Q1 25
$-8.3M
Q4 24
$-36.4M
Q3 24
$-7.5M
Q2 24
$-10.0M
Q1 24
$-9.8M
FCF Margin
CUE
CUE
KREF
KREF
Q4 25
Q3 25
Q2 25
-116.5%
Q1 25
-1976.7%
Q4 24
-2309.3%
Q3 24
-225.7%
Q2 24
-376.2%
Q1 24
-573.0%
Capex Intensity
CUE
CUE
KREF
KREF
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.9%
Q1 25
35.6%
Q4 24
4.2%
Q3 24
0.0%
Q2 24
0.4%
Q1 24
3.2%
Cash Conversion
CUE
CUE
KREF
KREF
Q4 25
-0.68×
Q3 25
1.34×
Q2 25
Q1 25
Q4 24
6.54×
Q3 24
Q2 24
1.19×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CUE
CUE

Immuno Scape Collaboration And License Agreement$9.5M43%
BI Collaboration And License Agreement$8.1M37%
Other$4.3M20%

KREF
KREF

Segment breakdown not available.

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