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Side-by-side financial comparison of Cue Biopharma, Inc. (CUE) and TPG Mortgage Investment Trust, Inc. (MITT). Click either name above to swap in a different company.
Cue Biopharma, Inc. is the larger business by last-quarter revenue ($21.9M vs $20.4M, roughly 1.1× TPG Mortgage Investment Trust, Inc.). TPG Mortgage Investment Trust, Inc. runs the higher net margin — 65.0% vs 7.2%, a 57.7% gap on every dollar of revenue. On growth, Cue Biopharma, Inc. posted the faster year-over-year revenue change (1292.3% vs 17.7%). Over the past eight quarters, Cue Biopharma, Inc.'s revenue compounded faster (257.5% CAGR vs 9.1%).
Cue Biopharma is a clinical-stage biotechnology company focused on developing novel targeted immunotherapies for cancer, autoimmune disorders, and inflammatory diseases. Its proprietary platform enables precise T-cell activity modulation, with core operations in North America and global pharma partnerships to advance lead product candidates through clinical trials.
TPG Mortgage Investment Trust, Inc. is a real estate investment trust managed by global alternative asset firm TPG. It primarily invests in residential and commercial mortgage-backed securities, performing and non-performing mortgage loans, and other credit-linked real estate assets, with its core market being the United States. It generates returns via net interest income from holdings and strategic asset disposition gains.
CUE vs MITT — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $21.9M | $20.4M |
| Net Profit | $1.6M | $13.3M |
| Gross Margin | — | — |
| Operating Margin | 9.0% | 67.1% |
| Net Margin | 7.2% | 65.0% |
| Revenue YoY | 1292.3% | 17.7% |
| Net Profit YoY | 116.7% | -7.0% |
| EPS (diluted) | $0.05 | $0.27 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $21.9M | $20.4M | ||
| Q3 25 | $2.1M | $19.5M | ||
| Q2 25 | $3.0M | $17.8M | ||
| Q1 25 | $421.0K | $18.8M | ||
| Q4 24 | $1.6M | $17.4M | ||
| Q3 24 | $3.3M | $14.9M | ||
| Q2 24 | $2.7M | $16.4M | ||
| Q1 24 | $1.7M | $17.2M |
| Q4 25 | $1.6M | $13.3M | ||
| Q3 25 | $-7.4M | $20.0M | ||
| Q2 25 | $-8.5M | $3.9M | ||
| Q1 25 | $-12.3M | $11.5M | ||
| Q4 24 | — | $14.3M | ||
| Q3 24 | $-8.7M | $16.6M | ||
| Q2 24 | $-10.2M | $3.9M | ||
| Q1 24 | $-12.3M | $20.9M |
| Q4 25 | 9.0% | 67.1% | ||
| Q3 25 | -353.4% | — | ||
| Q2 25 | -292.3% | 20.9% | ||
| Q1 25 | -2921.4% | 54.6% | ||
| Q4 24 | — | 76.7% | ||
| Q3 24 | -264.2% | — | ||
| Q2 24 | -390.6% | 18.4% | ||
| Q1 24 | -737.8% | — |
| Q4 25 | 7.2% | 65.0% | ||
| Q3 25 | -346.6% | 102.5% | ||
| Q2 25 | -287.1% | 22.2% | ||
| Q1 25 | -2911.4% | 60.9% | ||
| Q4 24 | — | 82.2% | ||
| Q3 24 | -259.6% | 111.3% | ||
| Q2 24 | -382.7% | 24.0% | ||
| Q1 24 | -719.1% | 121.6% |
| Q4 25 | $0.05 | $0.27 | ||
| Q3 25 | $-0.07 | $0.47 | ||
| Q2 25 | $-0.09 | $-0.05 | ||
| Q1 25 | $-0.17 | $0.21 | ||
| Q4 24 | — | $0.30 | ||
| Q3 24 | $-0.17 | $0.40 | ||
| Q2 24 | $-0.20 | $-0.02 | ||
| Q1 24 | $-0.25 | $0.55 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $27.1M | $57.8M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $26.4M | $560.7M |
| Total Assets | $42.2M | $8.7B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $27.1M | $57.8M | ||
| Q3 25 | $11.7M | $59.0M | ||
| Q2 25 | $27.5M | $88.7M | ||
| Q1 25 | $13.1M | $115.5M | ||
| Q4 24 | $22.5M | $118.7M | ||
| Q3 24 | $32.4M | $102.5M | ||
| Q2 24 | $30.0M | $120.9M | ||
| Q1 24 | $41.0M | $100.3M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | $1.0M | — | ||
| Q2 24 | $2.0M | — | ||
| Q1 24 | $3.0M | — |
| Q4 25 | $26.4M | $560.7M | ||
| Q3 25 | $13.2M | $559.8M | ||
| Q2 25 | $18.2M | $536.4M | ||
| Q1 25 | $6.6M | $543.9M | ||
| Q4 24 | $17.5M | $543.4M | ||
| Q3 24 | $25.4M | $540.1M | ||
| Q2 24 | $21.6M | $533.5M | ||
| Q1 24 | $30.0M | $539.6M |
| Q4 25 | $42.2M | $8.7B | ||
| Q3 25 | $31.6M | $9.0B | ||
| Q2 25 | $40.7M | $7.5B | ||
| Q1 25 | $22.3M | $7.3B | ||
| Q4 24 | $32.2M | $6.9B | ||
| Q3 24 | $44.8M | $7.0B | ||
| Q2 24 | $42.3M | $7.1B | ||
| Q1 24 | $54.0M | $6.4B |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 0.04× | — | ||
| Q2 24 | 0.09× | — | ||
| Q1 24 | 0.10× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-1.1M | $59.6M |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | -0.68× | 4.48× |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-1.1M | $59.6M | ||
| Q3 25 | $-9.0M | $17.4M | ||
| Q2 25 | $-3.4M | $11.5M | ||
| Q1 25 | $-8.2M | $12.0M | ||
| Q4 24 | $-36.3M | $55.8M | ||
| Q3 24 | $-7.5M | $14.5M | ||
| Q2 24 | $-10.0M | $13.7M | ||
| Q1 24 | $-9.8M | $12.0M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | $-3.4M | — | ||
| Q1 25 | $-8.3M | — | ||
| Q4 24 | $-36.4M | — | ||
| Q3 24 | $-7.5M | — | ||
| Q2 24 | $-10.0M | — | ||
| Q1 24 | $-9.8M | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | -116.5% | — | ||
| Q1 25 | -1976.7% | — | ||
| Q4 24 | -2309.3% | — | ||
| Q3 24 | -225.7% | — | ||
| Q2 24 | -376.2% | — | ||
| Q1 24 | -573.0% | — |
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.9% | — | ||
| Q1 25 | 35.6% | — | ||
| Q4 24 | 4.2% | — | ||
| Q3 24 | 0.0% | — | ||
| Q2 24 | 0.4% | — | ||
| Q1 24 | 3.2% | — |
| Q4 25 | -0.68× | 4.48× | ||
| Q3 25 | — | 0.87× | ||
| Q2 25 | — | 2.92× | ||
| Q1 25 | — | 1.05× | ||
| Q4 24 | — | 3.91× | ||
| Q3 24 | — | 0.87× | ||
| Q2 24 | — | 3.50× | ||
| Q1 24 | — | 0.57× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CUE
| Immuno Scape Collaboration And License Agreement | $9.5M | 43% |
| BI Collaboration And License Agreement | $8.1M | 37% |
| Other | $4.3M | 20% |
MITT
Segment breakdown not available.
