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Side-by-side financial comparison of Cue Biopharma, Inc. (CUE) and TOP SHIPS INC. (TOPS). Click either name above to swap in a different company.

TOP SHIPS INC. is the larger business by last-quarter revenue ($36.6M vs $21.9M, roughly 1.7× Cue Biopharma, Inc.). Cue Biopharma, Inc. runs the higher net margin — 7.2% vs -12.2%, a 19.5% gap on every dollar of revenue.

Cue Biopharma is a clinical-stage biotechnology company focused on developing novel targeted immunotherapies for cancer, autoimmune disorders, and inflammatory diseases. Its proprietary platform enables precise T-cell activity modulation, with core operations in North America and global pharma partnerships to advance lead product candidates through clinical trials.

Top Ships Inc. is a supply chain maritime transportation operations management company responsible for seaborne trade of raw materials. The company was founded by Evangelos J. Pistiolis on January 10, 2000 and is headquartered in Maroussi, Greece.

CUE vs TOPS — Head-to-Head

Bigger by revenue
TOPS
TOPS
1.7× larger
TOPS
$36.6M
$21.9M
CUE
Higher net margin
CUE
CUE
19.5% more per $
CUE
7.2%
-12.2%
TOPS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CUE
CUE
TOPS
TOPS
Revenue
$21.9M
$36.6M
Net Profit
$1.6M
$-4.5M
Gross Margin
Operating Margin
9.0%
22.0%
Net Margin
7.2%
-12.2%
Revenue YoY
1292.3%
Net Profit YoY
116.7%
EPS (diluted)
$0.05
$-0.96

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CUE
CUE
TOPS
TOPS
Q4 25
$21.9M
$36.6M
Q3 25
$2.1M
Q2 25
$3.0M
Q1 25
$421.0K
Q4 24
$1.6M
Q3 24
$3.3M
Q2 24
$2.7M
Q1 24
$1.7M
Net Profit
CUE
CUE
TOPS
TOPS
Q4 25
$1.6M
$-4.5M
Q3 25
$-7.4M
Q2 25
$-8.5M
Q1 25
$-12.3M
Q4 24
Q3 24
$-8.7M
Q2 24
$-10.2M
Q1 24
$-12.3M
Operating Margin
CUE
CUE
TOPS
TOPS
Q4 25
9.0%
22.0%
Q3 25
-353.4%
Q2 25
-292.3%
Q1 25
-2921.4%
Q4 24
Q3 24
-264.2%
Q2 24
-390.6%
Q1 24
-737.8%
Net Margin
CUE
CUE
TOPS
TOPS
Q4 25
7.2%
-12.2%
Q3 25
-346.6%
Q2 25
-287.1%
Q1 25
-2911.4%
Q4 24
Q3 24
-259.6%
Q2 24
-382.7%
Q1 24
-719.1%
EPS (diluted)
CUE
CUE
TOPS
TOPS
Q4 25
$0.05
$-0.96
Q3 25
$-0.07
Q2 25
$-0.09
Q1 25
$-0.17
Q4 24
Q3 24
$-0.17
Q2 24
$-0.20
Q1 24
$-0.25

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CUE
CUE
TOPS
TOPS
Cash + ST InvestmentsLiquidity on hand
$27.1M
$20.4M
Total DebtLower is stronger
$216.6M
Stockholders' EquityBook value
$26.4M
$89.2M
Total Assets
$42.2M
$333.6M
Debt / EquityLower = less leverage
2.43×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CUE
CUE
TOPS
TOPS
Q4 25
$27.1M
$20.4M
Q3 25
$11.7M
Q2 25
$27.5M
Q1 25
$13.1M
Q4 24
$22.5M
Q3 24
$32.4M
Q2 24
$30.0M
Q1 24
$41.0M
Total Debt
CUE
CUE
TOPS
TOPS
Q4 25
$216.6M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
$1.0M
Q2 24
$2.0M
Q1 24
$3.0M
Stockholders' Equity
CUE
CUE
TOPS
TOPS
Q4 25
$26.4M
$89.2M
Q3 25
$13.2M
Q2 25
$18.2M
Q1 25
$6.6M
Q4 24
$17.5M
Q3 24
$25.4M
Q2 24
$21.6M
Q1 24
$30.0M
Total Assets
CUE
CUE
TOPS
TOPS
Q4 25
$42.2M
$333.6M
Q3 25
$31.6M
Q2 25
$40.7M
Q1 25
$22.3M
Q4 24
$32.2M
Q3 24
$44.8M
Q2 24
$42.3M
Q1 24
$54.0M
Debt / Equity
CUE
CUE
TOPS
TOPS
Q4 25
2.43×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
0.04×
Q2 24
0.09×
Q1 24
0.10×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CUE
CUE
TOPS
TOPS
Operating Cash FlowLast quarter
$-1.1M
$26.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
-0.68×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CUE
CUE
TOPS
TOPS
Q4 25
$-1.1M
$26.4M
Q3 25
$-9.0M
Q2 25
$-3.4M
Q1 25
$-8.2M
Q4 24
$-36.3M
Q3 24
$-7.5M
Q2 24
$-10.0M
Q1 24
$-9.8M
Free Cash Flow
CUE
CUE
TOPS
TOPS
Q4 25
Q3 25
Q2 25
$-3.4M
Q1 25
$-8.3M
Q4 24
$-36.4M
Q3 24
$-7.5M
Q2 24
$-10.0M
Q1 24
$-9.8M
FCF Margin
CUE
CUE
TOPS
TOPS
Q4 25
Q3 25
Q2 25
-116.5%
Q1 25
-1976.7%
Q4 24
-2309.3%
Q3 24
-225.7%
Q2 24
-376.2%
Q1 24
-573.0%
Capex Intensity
CUE
CUE
TOPS
TOPS
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.9%
Q1 25
35.6%
Q4 24
4.2%
Q3 24
0.0%
Q2 24
0.4%
Q1 24
3.2%
Cash Conversion
CUE
CUE
TOPS
TOPS
Q4 25
-0.68×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CUE
CUE

Immuno Scape Collaboration And License Agreement$9.5M43%
BI Collaboration And License Agreement$8.1M37%
Other$4.3M20%

TOPS
TOPS

Segment breakdown not available.

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