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Side-by-side financial comparison of Delek US Holdings, Inc. (DK) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.
Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $2.6B, roughly 1.1× Delek US Holdings, Inc.). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs -7.7%, a 42.2% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs -4.9%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs -10.8%).
Delek US Holdings, Inc. is an oil refining, logistics and biofuels company founded in 2001 and headquartered in Brentwood, Tennessee.
Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.
DK vs VRTX — Head-to-Head
Income Statement — Q1 FY2026 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $2.6B | $3.0B |
| Net Profit | $-201.3M | $1.0B |
| Gross Margin | -5.8% | 86.8% |
| Operating Margin | — | 38.1% |
| Net Margin | -7.7% | 34.5% |
| Revenue YoY | -4.9% | 7.8% |
| Net Profit YoY | — | 59.6% |
| EPS (diluted) | $-3.34 | $4.02 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $2.6B | $3.0B | ||
| Q4 25 | $2.4B | $3.2B | ||
| Q3 25 | $2.9B | $3.1B | ||
| Q2 25 | $2.8B | $3.0B | ||
| Q1 25 | $2.6B | $2.8B | ||
| Q4 24 | $2.4B | $2.9B | ||
| Q3 24 | $3.0B | $2.8B | ||
| Q2 24 | $3.3B | $2.6B |
| Q1 26 | $-201.3M | $1.0B | ||
| Q4 25 | $78.3M | $1.2B | ||
| Q3 25 | $178.0M | $1.1B | ||
| Q2 25 | $-106.4M | $1.0B | ||
| Q1 25 | $-172.7M | $646.3M | ||
| Q4 24 | $-413.8M | $913.0M | ||
| Q3 24 | $-76.8M | $1.0B | ||
| Q2 24 | $-37.2M | $-3.6B |
| Q1 26 | -5.8% | 86.8% | ||
| Q4 25 | 9.3% | 85.4% | ||
| Q3 25 | 13.8% | 86.5% | ||
| Q2 25 | 1.9% | 86.3% | ||
| Q1 25 | -2.4% | 86.9% | ||
| Q4 24 | -5.7% | 85.5% | ||
| Q3 24 | -0.7% | 85.8% | ||
| Q2 24 | 0.5% | 85.9% |
| Q1 26 | — | 38.1% | ||
| Q4 25 | 6.8% | 37.8% | ||
| Q3 25 | 10.2% | 38.6% | ||
| Q2 25 | -1.2% | 38.8% | ||
| Q1 25 | -4.8% | 22.7% | ||
| Q4 24 | -17.0% | 35.2% | ||
| Q3 24 | -4.0% | 40.3% | ||
| Q2 24 | 0.1% | -132.9% |
| Q1 26 | -7.7% | 34.5% | ||
| Q4 25 | 3.2% | 37.3% | ||
| Q3 25 | 6.2% | 35.2% | ||
| Q2 25 | -3.8% | 34.8% | ||
| Q1 25 | -6.5% | 23.3% | ||
| Q4 24 | -17.4% | 31.4% | ||
| Q3 24 | -2.5% | 37.7% | ||
| Q2 24 | -1.1% | -135.8% |
| Q1 26 | $-3.34 | $4.02 | ||
| Q4 25 | $1.23 | $4.64 | ||
| Q3 25 | $2.93 | $4.20 | ||
| Q2 25 | $-1.76 | $3.99 | ||
| Q1 25 | $-2.78 | $2.49 | ||
| Q4 24 | $-6.48 | $3.62 | ||
| Q3 24 | $-1.20 | $4.01 | ||
| Q2 24 | $-0.58 | $-13.92 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $624.1M | — |
| Total DebtLower is stronger | $3.2B | — |
| Stockholders' EquityBook value | $302.0M | $19.4B |
| Total Assets | $7.6B | $26.5B |
| Debt / EquityLower = less leverage | 10.54× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $624.1M | — | ||
| Q4 25 | $625.8M | $6.6B | ||
| Q3 25 | $630.9M | $6.3B | ||
| Q2 25 | $615.5M | $6.4B | ||
| Q1 25 | $623.8M | $6.2B | ||
| Q4 24 | $735.6M | $6.1B | ||
| Q3 24 | $1.0B | $6.5B | ||
| Q2 24 | $657.9M | $5.8B |
| Q1 26 | $3.2B | — | ||
| Q4 25 | $3.2B | — | ||
| Q3 25 | $3.2B | — | ||
| Q2 25 | $3.1B | — | ||
| Q1 25 | $3.0B | — | ||
| Q4 24 | $2.8B | — | ||
| Q3 24 | $2.8B | — | ||
| Q2 24 | $2.5B | — |
| Q1 26 | $302.0M | $19.4B | ||
| Q4 25 | $547.3M | $18.7B | ||
| Q3 25 | $444.8M | $17.3B | ||
| Q2 25 | $294.9M | $17.2B | ||
| Q1 25 | $429.4M | $16.5B | ||
| Q4 24 | $575.2M | $16.4B | ||
| Q3 24 | $875.4M | $15.6B | ||
| Q2 24 | $982.8M | $14.8B |
| Q1 26 | $7.6B | $26.5B | ||
| Q4 25 | $6.8B | $25.6B | ||
| Q3 25 | $7.1B | $24.9B | ||
| Q2 25 | $7.1B | $24.0B | ||
| Q1 25 | $6.9B | $22.9B | ||
| Q4 24 | $6.7B | $22.5B | ||
| Q3 24 | $7.0B | $22.2B | ||
| Q2 24 | $6.9B | $20.1B |
| Q1 26 | 10.54× | — | ||
| Q4 25 | 5.91× | — | ||
| Q3 25 | 7.14× | — | ||
| Q2 25 | 10.51× | — | ||
| Q1 25 | 7.07× | — | ||
| Q4 24 | 4.81× | — | ||
| Q3 24 | 3.19× | — | ||
| Q2 24 | 2.50× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
DK
Segment breakdown not available.
VRTX
| TRIKAFTA/KAFTRIO | $2.4B | 79% |
| ALYFTREK | $424.4M | 14% |
| Other | $135.9M | 5% |
| CASGEVY | $42.9M | 1% |
| Vertex recorded | $29.0M | 1% |
