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Side-by-side financial comparison of Ginkgo Bioworks Holdings, Inc. (DNA) and FINANCIAL INSTITUTIONS INC (FISI). Click either name above to swap in a different company.

FINANCIAL INSTITUTIONS INC is the larger business by last-quarter revenue ($62.7M vs $33.4M, roughly 1.9× Ginkgo Bioworks Holdings, Inc.). Over the past eight quarters, FINANCIAL INSTITUTIONS INC's revenue compounded faster (-2.0% CAGR vs -6.2%).

Ginkgo Bioworks Holdings, Inc. is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It...

The Mizuho Financial Group, Inc. , known from 2000 to 2003 as Mizuho Holdings and abbreviated as MHFG or simply Mizuho, is a Japanese banking holding company headquartered in the Ōtemachi district of Chiyoda, Tokyo, Japan. The group was formed in 2000–2002 by merger of Dai-Ichi Kangyo Bank, Fuji Bank, and Industrial Bank of Japan. The name mizuho (瑞穂) literally means "abundant rice" in Japanese and "harvest" in the figurative sense.

DNA vs FISI — Head-to-Head

Bigger by revenue
FISI
FISI
1.9× larger
FISI
$62.7M
$33.4M
DNA
Faster 2-yr revenue CAGR
FISI
FISI
Annualised
FISI
-2.0%
-6.2%
DNA

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
DNA
DNA
FISI
FISI
Revenue
$33.4M
$62.7M
Net Profit
$21.0M
Gross Margin
Operating Margin
-211.9%
Net Margin
33.5%
Revenue YoY
-23.8%
Net Profit YoY
24.3%
EPS (diluted)
$-1.41
$1.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DNA
DNA
FISI
FISI
Q1 26
$62.7M
Q4 25
$33.4M
$64.1M
Q3 25
$38.8M
$63.8M
Q2 25
$49.6M
$59.7M
Q1 25
$48.3M
$57.2M
Q4 24
$43.8M
$41.6M
Q3 24
$89.0M
$50.1M
Q2 24
$56.2M
$65.2M
Net Profit
DNA
DNA
FISI
FISI
Q1 26
$21.0M
Q4 25
$20.0M
Q3 25
$-80.8M
$20.5M
Q2 25
$-60.3M
$17.5M
Q1 25
$-91.0M
$16.9M
Q4 24
$-82.8M
Q3 24
$-56.4M
$13.5M
Q2 24
$-217.2M
$25.6M
Operating Margin
DNA
DNA
FISI
FISI
Q1 26
Q4 25
-211.9%
37.4%
Q3 25
-231.8%
39.5%
Q2 25
-132.1%
36.0%
Q1 25
-184.1%
36.0%
Q4 24
-236.3%
-276.9%
Q3 24
-62.0%
29.0%
Q2 24
-396.7%
46.2%
Net Margin
DNA
DNA
FISI
FISI
Q1 26
33.5%
Q4 25
38.3%
Q3 25
-207.9%
32.1%
Q2 25
-121.6%
29.3%
Q1 25
-188.2%
29.5%
Q4 24
-198.9%
Q3 24
-63.3%
26.9%
Q2 24
-386.4%
39.3%
EPS (diluted)
DNA
DNA
FISI
FISI
Q1 26
$1.04
Q4 25
$-1.41
$0.96
Q3 25
$-1.45
$0.99
Q2 25
$-1.10
$0.85
Q1 25
$-1.68
$0.81
Q4 24
$-1.91
$-5.32
Q3 24
$-1.08
$0.84
Q2 24
$-4.23
$1.62

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DNA
DNA
FISI
FISI
Cash + ST InvestmentsLiquidity on hand
$422.6M
$85.5M
Total DebtLower is stronger
$114.0M
Stockholders' EquityBook value
$508.6M
Total Assets
$1.1B
$6.3B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DNA
DNA
FISI
FISI
Q1 26
$85.5M
Q4 25
$422.6M
$108.8M
Q3 25
$495.5M
$185.9M
Q2 25
$559.4M
$93.0M
Q1 25
$325.3M
$167.4M
Q4 24
$561.6M
$87.3M
Q3 24
$616.2M
Q2 24
$730.4M
Total Debt
DNA
DNA
FISI
FISI
Q1 26
$114.0M
Q4 25
$193.7M
Q3 25
$115.0M
Q2 25
$115.0M
Q1 25
$124.9M
Q4 24
$124.8M
Q3 24
$124.8M
Q2 24
$124.7M
Stockholders' Equity
DNA
DNA
FISI
FISI
Q1 26
Q4 25
$508.6M
$628.9M
Q3 25
$559.8M
$621.7M
Q2 25
$613.0M
$601.7M
Q1 25
$647.4M
$589.9M
Q4 24
$716.1M
$569.0M
Q3 24
$797.9M
$500.3M
Q2 24
$833.1M
$467.7M
Total Assets
DNA
DNA
FISI
FISI
Q1 26
$6.3B
Q4 25
$1.1B
$6.3B
Q3 25
$1.2B
$6.3B
Q2 25
$1.2B
$6.1B
Q1 25
$1.3B
$6.3B
Q4 24
$1.4B
$6.1B
Q3 24
$1.5B
$6.2B
Q2 24
$1.6B
$6.1B
Debt / Equity
DNA
DNA
FISI
FISI
Q1 26
Q4 25
0.31×
Q3 25
0.18×
Q2 25
0.19×
Q1 25
0.21×
Q4 24
0.22×
Q3 24
0.25×
Q2 24
0.27×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DNA
DNA
FISI
FISI
Operating Cash FlowLast quarter
$-47.7M
Free Cash FlowOCF − Capex
$-47.7M
FCF MarginFCF / Revenue
-142.8%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DNA
DNA
FISI
FISI
Q1 26
Q4 25
$-47.7M
$18.8M
Q3 25
$-31.6M
$-6.9M
Q2 25
$-40.3M
$-5.7M
Q1 25
$-51.5M
$10.0M
Q4 24
$-42.4M
$77.1M
Q3 24
$-103.5M
$2.1M
Q2 24
$-84.4M
$35.7M
Free Cash Flow
DNA
DNA
FISI
FISI
Q1 26
Q4 25
$-47.7M
$13.3M
Q3 25
$-7.9M
Q2 25
$-40.3M
$-7.3M
Q1 25
$-59.1M
$9.2M
Q4 24
$-56.1M
$72.2M
Q3 24
$-118.6M
$-299.0K
Q2 24
$-111.4M
$34.7M
FCF Margin
DNA
DNA
FISI
FISI
Q1 26
Q4 25
-142.8%
20.7%
Q3 25
-12.4%
Q2 25
-81.2%
-12.3%
Q1 25
-122.4%
16.1%
Q4 24
-128.0%
173.3%
Q3 24
-133.2%
-0.6%
Q2 24
-198.2%
53.3%
Capex Intensity
DNA
DNA
FISI
FISI
Q1 26
Q4 25
0.0%
8.7%
Q3 25
0.0%
1.6%
Q2 25
0.1%
2.7%
Q1 25
15.8%
1.4%
Q4 24
31.3%
11.9%
Q3 24
16.9%
4.9%
Q2 24
48.1%
1.5%
Cash Conversion
DNA
DNA
FISI
FISI
Q1 26
Q4 25
0.94×
Q3 25
-0.34×
Q2 25
-0.33×
Q1 25
0.59×
Q4 24
Q3 24
0.16×
Q2 24
1.39×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DNA
DNA

Cell Engineering Segment$26.0M78%
Other$7.4M22%

FISI
FISI

Net Interest Income$52.0M83%
Noninterest Income$10.7M17%

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