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Side-by-side financial comparison of Ginkgo Bioworks Holdings, Inc. (DNA) and INNOVATIVE SOLUTIONS & SUPPORT INC (ISSC). Click either name above to swap in a different company.

Ginkgo Bioworks Holdings, Inc. is the larger business by last-quarter revenue ($33.4M vs $21.8M, roughly 1.5× INNOVATIVE SOLUTIONS & SUPPORT INC). On growth, INNOVATIVE SOLUTIONS & SUPPORT INC posted the faster year-over-year revenue change (36.6% vs -23.8%). INNOVATIVE SOLUTIONS & SUPPORT INC produced more free cash flow last quarter ($7.0M vs $-47.7M). Over the past eight quarters, INNOVATIVE SOLUTIONS & SUPPORT INC's revenue compounded faster (42.5% CAGR vs -6.2%).

Ginkgo Bioworks Holdings, Inc. is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It...

Motorola Solutions, Inc., is an American technology company that provides safety and security products and services. Headquartered in Chicago, Illinois, the company provides critical communications, video security, and command center technologies, used by public safety agencies and enterprises. It was formed in 2011 by the division of Motorola, Inc., and is its legal successor; the former company's mobile phone division was spun off as Motorola Mobility, now part of Chinese technology company...

DNA vs ISSC — Head-to-Head

Bigger by revenue
DNA
DNA
1.5× larger
DNA
$33.4M
$21.8M
ISSC
Growing faster (revenue YoY)
ISSC
ISSC
+60.4% gap
ISSC
36.6%
-23.8%
DNA
More free cash flow
ISSC
ISSC
$54.7M more FCF
ISSC
$7.0M
$-47.7M
DNA
Faster 2-yr revenue CAGR
ISSC
ISSC
Annualised
ISSC
42.5%
-6.2%
DNA

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
DNA
DNA
ISSC
ISSC
Revenue
$33.4M
$21.8M
Net Profit
$4.1M
Gross Margin
54.5%
Operating Margin
-211.9%
28.9%
Net Margin
18.6%
Revenue YoY
-23.8%
36.6%
Net Profit YoY
451.4%
EPS (diluted)
$-1.41
$0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DNA
DNA
ISSC
ISSC
Q4 25
$33.4M
$21.8M
Q3 25
$38.8M
$22.2M
Q2 25
$49.6M
$24.1M
Q1 25
$48.3M
$21.9M
Q4 24
$43.8M
$16.0M
Q3 24
$89.0M
$15.4M
Q2 24
$56.2M
$11.8M
Q1 24
$37.9M
$10.7M
Net Profit
DNA
DNA
ISSC
ISSC
Q4 25
$4.1M
Q3 25
$-80.8M
$7.1M
Q2 25
$-60.3M
$2.4M
Q1 25
$-91.0M
$5.3M
Q4 24
$736.2K
Q3 24
$-56.4M
$3.2M
Q2 24
$-217.2M
$1.6M
Q1 24
$-165.9M
$1.2M
Gross Margin
DNA
DNA
ISSC
ISSC
Q4 25
54.5%
Q3 25
63.2%
Q2 25
35.5%
Q1 25
51.4%
Q4 24
41.4%
Q3 24
55.4%
Q2 24
53.4%
Q1 24
52.0%
Operating Margin
DNA
DNA
ISSC
ISSC
Q4 25
-211.9%
28.9%
Q3 25
-231.8%
37.0%
Q2 25
-132.1%
14.6%
Q1 25
-184.1%
31.8%
Q4 24
-236.3%
8.4%
Q3 24
-62.0%
28.4%
Q2 24
-396.7%
17.3%
Q1 24
-469.1%
15.3%
Net Margin
DNA
DNA
ISSC
ISSC
Q4 25
18.6%
Q3 25
-207.9%
32.0%
Q2 25
-121.6%
10.1%
Q1 25
-188.2%
24.3%
Q4 24
4.6%
Q3 24
-63.3%
20.7%
Q2 24
-386.4%
13.2%
Q1 24
-437.3%
11.3%
EPS (diluted)
DNA
DNA
ISSC
ISSC
Q4 25
$-1.41
$0.22
Q3 25
$-1.45
$0.40
Q2 25
$-1.10
$0.14
Q1 25
$-1.68
$0.30
Q4 24
$-1.91
$0.04
Q3 24
$-1.08
$0.18
Q2 24
$-4.23
$0.09
Q1 24
$-3.32
$0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DNA
DNA
ISSC
ISSC
Cash + ST InvestmentsLiquidity on hand
$422.6M
$8.3M
Total DebtLower is stronger
$23.8M
Stockholders' EquityBook value
$508.6M
$68.7M
Total Assets
$1.1B
$109.9M
Debt / EquityLower = less leverage
0.35×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DNA
DNA
ISSC
ISSC
Q4 25
$422.6M
$8.3M
Q3 25
$495.5M
$2.7M
Q2 25
$559.4M
$601.8K
Q1 25
$325.3M
$1.2M
Q4 24
$561.6M
$604.6K
Q3 24
$616.2M
$539.0K
Q2 24
$730.4M
$521.0K
Q1 24
$840.4M
$574.1K
Total Debt
DNA
DNA
ISSC
ISSC
Q4 25
$23.8M
Q3 25
$24.4M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
DNA
DNA
ISSC
ISSC
Q4 25
$508.6M
$68.7M
Q3 25
$559.8M
$64.6M
Q2 25
$613.0M
$56.8M
Q1 25
$647.4M
$53.5M
Q4 24
$716.1M
$47.8M
Q3 24
$797.9M
$46.6M
Q2 24
$833.1M
$43.2M
Q1 24
$987.3M
$41.4M
Total Assets
DNA
DNA
ISSC
ISSC
Q4 25
$1.1B
$109.9M
Q3 25
$1.2B
$103.4M
Q2 25
$1.2B
$91.8M
Q1 25
$1.3B
$89.9M
Q4 24
$1.4B
$81.3M
Q3 24
$1.5B
$82.4M
Q2 24
$1.6B
$59.8M
Q1 24
$1.6B
$57.6M
Debt / Equity
DNA
DNA
ISSC
ISSC
Q4 25
0.35×
Q3 25
0.38×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DNA
DNA
ISSC
ISSC
Operating Cash FlowLast quarter
$-47.7M
$8.2M
Free Cash FlowOCF − Capex
$-47.7M
$7.0M
FCF MarginFCF / Revenue
-142.8%
32.3%
Capex IntensityCapex / Revenue
0.0%
5.1%
Cash ConversionOCF / Net Profit
2.01×
TTM Free Cash FlowTrailing 4 quarters
$12.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DNA
DNA
ISSC
ISSC
Q4 25
$-47.7M
$8.2M
Q3 25
$-31.6M
$3.0M
Q2 25
$-40.3M
$7.2M
Q1 25
$-51.5M
$1.3M
Q4 24
$-42.4M
$1.8M
Q3 24
$-103.5M
$445.3K
Q2 24
$-84.4M
$934.1K
Q1 24
$-89.3M
$201.1K
Free Cash Flow
DNA
DNA
ISSC
ISSC
Q4 25
$-47.7M
$7.0M
Q3 25
$2.0M
Q2 25
$-40.3M
$3.5M
Q1 25
$-59.1M
$-267.7K
Q4 24
$-56.1M
$1.6M
Q3 24
$-118.6M
$299.5K
Q2 24
$-111.4M
$730.8K
Q1 24
$-96.0M
$75.4K
FCF Margin
DNA
DNA
ISSC
ISSC
Q4 25
-142.8%
32.3%
Q3 25
8.8%
Q2 25
-81.2%
14.6%
Q1 25
-122.4%
-1.2%
Q4 24
-128.0%
9.9%
Q3 24
-133.2%
1.9%
Q2 24
-198.2%
6.2%
Q1 24
-252.9%
0.7%
Capex Intensity
DNA
DNA
ISSC
ISSC
Q4 25
0.0%
5.1%
Q3 25
0.0%
4.5%
Q2 25
0.1%
15.3%
Q1 25
15.8%
7.1%
Q4 24
31.3%
1.6%
Q3 24
16.9%
0.9%
Q2 24
48.1%
1.7%
Q1 24
17.7%
1.2%
Cash Conversion
DNA
DNA
ISSC
ISSC
Q4 25
2.01×
Q3 25
0.42×
Q2 25
2.95×
Q1 25
0.24×
Q4 24
2.50×
Q3 24
0.14×
Q2 24
0.60×
Q1 24
0.17×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DNA
DNA

Cell Engineering Segment$26.0M78%
Other$7.4M22%

ISSC
ISSC

Products$13.6M62%
Services$8.2M38%

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