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Side-by-side financial comparison of Ginkgo Bioworks Holdings, Inc. (DNA) and Simulations Plus, Inc. (SLP). Click either name above to swap in a different company.

Ginkgo Bioworks Holdings, Inc. is the larger business by last-quarter revenue ($33.4M vs $18.4M, roughly 1.8× Simulations Plus, Inc.). On growth, Simulations Plus, Inc. posted the faster year-over-year revenue change (-2.7% vs -23.8%). Over the past eight quarters, Simulations Plus, Inc.'s revenue compounded faster (0.3% CAGR vs -6.2%).

Ginkgo Bioworks Holdings, Inc. is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It...

Simulations Plus, Inc. develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling and simulation software for the pharmaceutical and biotechnology, industrial chemicals, cosmetics, food ingredients, and herbicide industries. In September 2014, the company acquired Cognigen Corporation, a provider of clinical trial data analysis and consulting services.

DNA vs SLP — Head-to-Head

Bigger by revenue
DNA
DNA
1.8× larger
DNA
$33.4M
$18.4M
SLP
Growing faster (revenue YoY)
SLP
SLP
+21.2% gap
SLP
-2.7%
-23.8%
DNA
Faster 2-yr revenue CAGR
SLP
SLP
Annualised
SLP
0.3%
-6.2%
DNA

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
DNA
DNA
SLP
SLP
Revenue
$33.4M
$18.4M
Net Profit
$676.0K
Gross Margin
59.1%
Operating Margin
-211.9%
3.9%
Net Margin
3.7%
Revenue YoY
-23.8%
-2.7%
Net Profit YoY
228.2%
EPS (diluted)
$-1.41
$0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DNA
DNA
SLP
SLP
Q4 25
$33.4M
$18.4M
Q3 25
$38.8M
$17.5M
Q2 25
$49.6M
$20.4M
Q1 25
$48.3M
$22.4M
Q4 24
$43.8M
$18.9M
Q3 24
$89.0M
$18.7M
Q2 24
$56.2M
$18.5M
Q1 24
$37.9M
$18.3M
Net Profit
DNA
DNA
SLP
SLP
Q4 25
$676.0K
Q3 25
$-80.8M
$-681.0K
Q2 25
$-60.3M
$-67.3M
Q1 25
$-91.0M
$3.1M
Q4 24
$206.0K
Q3 24
$-56.4M
$843.0K
Q2 24
$-217.2M
$3.1M
Q1 24
$-165.9M
$4.0M
Gross Margin
DNA
DNA
SLP
SLP
Q4 25
59.1%
Q3 25
56.4%
Q2 25
64.0%
Q1 25
58.5%
Q4 24
54.0%
Q3 24
36.6%
Q2 24
71.5%
Q1 24
72.2%
Operating Margin
DNA
DNA
SLP
SLP
Q4 25
-211.9%
3.9%
Q3 25
-231.8%
3.8%
Q2 25
-132.1%
-364.5%
Q1 25
-184.1%
12.1%
Q4 24
-236.3%
0.7%
Q3 24
-62.0%
-6.2%
Q2 24
-396.7%
10.1%
Q1 24
-469.1%
24.3%
Net Margin
DNA
DNA
SLP
SLP
Q4 25
3.7%
Q3 25
-207.9%
-3.9%
Q2 25
-121.6%
-330.6%
Q1 25
-188.2%
13.7%
Q4 24
1.1%
Q3 24
-63.3%
4.5%
Q2 24
-386.4%
16.9%
Q1 24
-437.3%
22.0%
EPS (diluted)
DNA
DNA
SLP
SLP
Q4 25
$-1.41
$0.03
Q3 25
$-1.45
$-0.03
Q2 25
$-1.10
$-3.35
Q1 25
$-1.68
$0.15
Q4 24
$-1.91
$0.01
Q3 24
$-1.08
$0.04
Q2 24
$-4.23
$0.15
Q1 24
$-3.32
$0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DNA
DNA
SLP
SLP
Cash + ST InvestmentsLiquidity on hand
$422.6M
$35.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$508.6M
$127.1M
Total Assets
$1.1B
$137.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DNA
DNA
SLP
SLP
Q4 25
$422.6M
$35.7M
Q3 25
$495.5M
$32.4M
Q2 25
$559.4M
$28.4M
Q1 25
$325.3M
$21.4M
Q4 24
$561.6M
$18.2M
Q3 24
$616.2M
$20.3M
Q2 24
$730.4M
$119.0M
Q1 24
$840.4M
$108.5M
Stockholders' Equity
DNA
DNA
SLP
SLP
Q4 25
$508.6M
$127.1M
Q3 25
$559.8M
$124.8M
Q2 25
$613.0M
$123.8M
Q1 25
$647.4M
$189.5M
Q4 24
$716.1M
$184.7M
Q3 24
$797.9M
$182.4M
Q2 24
$833.1M
$180.9M
Q1 24
$987.3M
$177.0M
Total Assets
DNA
DNA
SLP
SLP
Q4 25
$1.1B
$137.8M
Q3 25
$1.2B
$131.9M
Q2 25
$1.2B
$134.4M
Q1 25
$1.3B
$201.4M
Q4 24
$1.4B
$196.9M
Q3 24
$1.5B
$196.6M
Q2 24
$1.6B
$192.7M
Q1 24
$1.6B
$194.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DNA
DNA
SLP
SLP
Operating Cash FlowLast quarter
$-47.7M
$4.2M
Free Cash FlowOCF − Capex
$-47.7M
FCF MarginFCF / Revenue
-142.8%
Capex IntensityCapex / Revenue
0.0%
0.0%
Cash ConversionOCF / Net Profit
6.26×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DNA
DNA
SLP
SLP
Q4 25
$-47.7M
$4.2M
Q3 25
$-31.6M
$5.6M
Q2 25
$-40.3M
$8.1M
Q1 25
$-51.5M
$5.7M
Q4 24
$-42.4M
$-1.3M
Q3 24
$-103.5M
$1.7M
Q2 24
$-84.4M
$5.7M
Q1 24
$-89.3M
$5.8M
Free Cash Flow
DNA
DNA
SLP
SLP
Q4 25
$-47.7M
Q3 25
$5.3M
Q2 25
$-40.3M
$7.8M
Q1 25
$-59.1M
$5.6M
Q4 24
$-56.1M
$-1.4M
Q3 24
$-118.6M
$1.6M
Q2 24
$-111.4M
$5.6M
Q1 24
$-96.0M
$5.4M
FCF Margin
DNA
DNA
SLP
SLP
Q4 25
-142.8%
Q3 25
30.5%
Q2 25
-81.2%
38.5%
Q1 25
-122.4%
25.0%
Q4 24
-128.0%
-7.2%
Q3 24
-133.2%
8.8%
Q2 24
-198.2%
30.0%
Q1 24
-252.9%
29.4%
Capex Intensity
DNA
DNA
SLP
SLP
Q4 25
0.0%
0.0%
Q3 25
0.0%
1.5%
Q2 25
0.1%
1.5%
Q1 25
15.8%
0.3%
Q4 24
31.3%
0.5%
Q3 24
16.9%
0.1%
Q2 24
48.1%
0.6%
Q1 24
17.7%
2.4%
Cash Conversion
DNA
DNA
SLP
SLP
Q4 25
6.26×
Q3 25
Q2 25
Q1 25
1.84×
Q4 24
-6.18×
Q3 24
1.97×
Q2 24
1.81×
Q1 24
1.44×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DNA
DNA

Cell Engineering Segment$26.0M78%
Other$7.4M22%

SLP
SLP

Services Segment$9.5M52%
Development$7.2M39%
Discovery$1.3M7%

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