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Side-by-side financial comparison of Ginkgo Bioworks Holdings, Inc. (DNA) and SOUTHERN MISSOURI BANCORP, INC. (SMBC). Click either name above to swap in a different company.
SOUTHERN MISSOURI BANCORP, INC. is the larger business by last-quarter revenue ($49.6M vs $33.4M, roughly 1.5× Ginkgo Bioworks Holdings, Inc.). On growth, SOUTHERN MISSOURI BANCORP, INC. posted the faster year-over-year revenue change (10.3% vs -23.8%). SOUTHERN MISSOURI BANCORP, INC. produced more free cash flow last quarter ($20.2M vs $-47.7M). Over the past eight quarters, SOUTHERN MISSOURI BANCORP, INC.'s revenue compounded faster (11.3% CAGR vs -6.2%).
Ginkgo Bioworks Holdings, Inc. is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It...
U.S. Bancorp is an American multinational banking institution headquartered in Minneapolis, Minnesota and incorporated in Delaware. It is the 5th-largest bank in the United States as of 2025. As the largest bank in the Midwestern United States, it is considered systemically important by the Financial Stability Board. It is the parent company of its primary operating entity, U.S. Bank National Association, which does business as U.S. Bank. The company provides banking, investment, mortgage, tr...
DNA vs SMBC — Head-to-Head
Income Statement — Q4 FY2025 vs Q2 FY2026
| Metric | | |
|---|---|---|
| Revenue | $33.4M | $49.6M |
| Net Profit | — | $18.1M |
| Gross Margin | — | — |
| Operating Margin | -211.9% | 45.7% |
| Net Margin | — | 36.6% |
| Revenue YoY | -23.8% | 10.3% |
| Net Profit YoY | — | 23.9% |
| EPS (diluted) | $-1.41 | $1.62 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $33.4M | $49.6M | ||
| Q3 25 | $38.8M | $49.0M | ||
| Q2 25 | $49.6M | $47.6M | ||
| Q1 25 | $48.3M | $46.1M | ||
| Q4 24 | $43.8M | $45.0M | ||
| Q3 24 | $89.0M | $43.8M | ||
| Q2 24 | $56.2M | $42.9M | ||
| Q1 24 | $37.9M | $40.1M |
| Q4 25 | — | $18.1M | ||
| Q3 25 | $-80.8M | $15.7M | ||
| Q2 25 | $-60.3M | $15.8M | ||
| Q1 25 | $-91.0M | $15.7M | ||
| Q4 24 | — | $14.7M | ||
| Q3 24 | $-56.4M | $12.5M | ||
| Q2 24 | $-217.2M | $13.5M | ||
| Q1 24 | $-165.9M | $11.3M |
| Q4 25 | -211.9% | 45.7% | ||
| Q3 25 | -231.8% | 39.7% | ||
| Q2 25 | -132.1% | 40.2% | ||
| Q1 25 | -184.1% | 43.0% | ||
| Q4 24 | -236.3% | 42.7% | ||
| Q3 24 | -62.0% | 36.1% | ||
| Q2 24 | -396.7% | 39.6% | ||
| Q1 24 | -469.1% | 35.3% |
| Q4 25 | — | 36.6% | ||
| Q3 25 | -207.9% | 31.9% | ||
| Q2 25 | -121.6% | 33.2% | ||
| Q1 25 | -188.2% | 34.0% | ||
| Q4 24 | — | 32.6% | ||
| Q3 24 | -63.3% | 28.4% | ||
| Q2 24 | -386.4% | 31.6% | ||
| Q1 24 | -437.3% | 28.2% |
| Q4 25 | $-1.41 | $1.62 | ||
| Q3 25 | $-1.45 | $1.38 | ||
| Q2 25 | $-1.10 | $1.39 | ||
| Q1 25 | $-1.68 | $1.39 | ||
| Q4 24 | $-1.91 | $1.30 | ||
| Q3 24 | $-1.08 | $1.10 | ||
| Q2 24 | $-4.23 | $1.20 | ||
| Q1 24 | $-3.32 | $0.99 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $422.6M | $134.1M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $508.6M | $567.4M |
| Total Assets | $1.1B | $5.1B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $422.6M | $134.1M | ||
| Q3 25 | $495.5M | $124.1M | ||
| Q2 25 | $559.4M | $192.9M | ||
| Q1 25 | $325.3M | $226.9M | ||
| Q4 24 | $561.6M | $145.8M | ||
| Q3 24 | $616.2M | $75.3M | ||
| Q2 24 | $730.4M | $60.9M | ||
| Q1 24 | $840.4M | $168.3M |
| Q4 25 | $508.6M | $567.4M | ||
| Q3 25 | $559.8M | $560.2M | ||
| Q2 25 | $613.0M | $544.7M | ||
| Q1 25 | $647.4M | $528.8M | ||
| Q4 24 | $716.1M | $512.4M | ||
| Q3 24 | $797.9M | $505.6M | ||
| Q2 24 | $833.1M | $488.7M | ||
| Q1 24 | $987.3M | $479.6M |
| Q4 25 | $1.1B | $5.1B | ||
| Q3 25 | $1.2B | $5.0B | ||
| Q2 25 | $1.2B | $5.0B | ||
| Q1 25 | $1.3B | $5.0B | ||
| Q4 24 | $1.4B | $4.9B | ||
| Q3 24 | $1.5B | $4.7B | ||
| Q2 24 | $1.6B | $4.6B | ||
| Q1 24 | $1.6B | $4.6B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-47.7M | $21.3M |
| Free Cash FlowOCF − Capex | $-47.7M | $20.2M |
| FCF MarginFCF / Revenue | -142.8% | 40.6% |
| Capex IntensityCapex / Revenue | 0.0% | 2.2% |
| Cash ConversionOCF / Net Profit | — | 1.17× |
| TTM Free Cash FlowTrailing 4 quarters | — | $133.6M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-47.7M | $21.3M | ||
| Q3 25 | $-31.6M | $16.3M | ||
| Q2 25 | $-40.3M | $81.6M | ||
| Q1 25 | $-51.5M | $24.1M | ||
| Q4 24 | $-42.4M | $20.1M | ||
| Q3 24 | $-103.5M | $10.0M | ||
| Q2 24 | $-84.4M | $70.3M | ||
| Q1 24 | $-89.3M | $23.9M |
| Q4 25 | $-47.7M | $20.2M | ||
| Q3 25 | — | $15.4M | ||
| Q2 25 | $-40.3M | $75.3M | ||
| Q1 25 | $-59.1M | $22.7M | ||
| Q4 24 | $-56.1M | $18.2M | ||
| Q3 24 | $-118.6M | $8.6M | ||
| Q2 24 | $-111.4M | $61.2M | ||
| Q1 24 | $-96.0M | $19.6M |
| Q4 25 | -142.8% | 40.6% | ||
| Q3 25 | — | 31.4% | ||
| Q2 25 | -81.2% | 158.1% | ||
| Q1 25 | -122.4% | 49.3% | ||
| Q4 24 | -128.0% | 40.3% | ||
| Q3 24 | -133.2% | 19.5% | ||
| Q2 24 | -198.2% | 142.8% | ||
| Q1 24 | -252.9% | 48.8% |
| Q4 25 | 0.0% | 2.2% | ||
| Q3 25 | 0.0% | 1.8% | ||
| Q2 25 | 0.1% | 13.2% | ||
| Q1 25 | 15.8% | 3.0% | ||
| Q4 24 | 31.3% | 4.4% | ||
| Q3 24 | 16.9% | 3.3% | ||
| Q2 24 | 48.1% | 21.1% | ||
| Q1 24 | 17.7% | 10.8% |
| Q4 25 | — | 1.17× | ||
| Q3 25 | — | 1.04× | ||
| Q2 25 | — | 5.17× | ||
| Q1 25 | — | 1.54× | ||
| Q4 24 | — | 1.37× | ||
| Q3 24 | — | 0.80× | ||
| Q2 24 | — | 5.19× | ||
| Q1 24 | — | 2.11× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
DNA
| Cell Engineering Segment | $26.0M | 78% |
| Other | $7.4M | 22% |
SMBC
Segment breakdown not available.
