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Side-by-side financial comparison of Ginkgo Bioworks Holdings, Inc. (DNA) and TPG RE Finance Trust, Inc. (TRTX). Click either name above to swap in a different company.

TPG RE Finance Trust, Inc. is the larger business by last-quarter revenue ($35.0M vs $33.4M, roughly 1.0× Ginkgo Bioworks Holdings, Inc.). On growth, TPG RE Finance Trust, Inc. posted the faster year-over-year revenue change (0.9% vs -23.8%). Over the past eight quarters, TPG RE Finance Trust, Inc.'s revenue compounded faster (-5.1% CAGR vs -6.2%).

Ginkgo Bioworks Holdings, Inc. is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It...

TPG RE Finance Trust, Inc. is a commercial real estate finance firm primarily operating in the United States. It originates, underwrites and manages a portfolio of senior commercial mortgage loans and other real estate-linked debt instruments, serving commercial property owners and investors across multifamily, industrial, office and retail property segments.

DNA vs TRTX — Head-to-Head

Bigger by revenue
TRTX
TRTX
1.0× larger
TRTX
$35.0M
$33.4M
DNA
Growing faster (revenue YoY)
TRTX
TRTX
+24.7% gap
TRTX
0.9%
-23.8%
DNA
Faster 2-yr revenue CAGR
TRTX
TRTX
Annualised
TRTX
-5.1%
-6.2%
DNA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
DNA
DNA
TRTX
TRTX
Revenue
$33.4M
$35.0M
Net Profit
$4.0M
Gross Margin
Operating Margin
-211.9%
11.6%
Net Margin
15.6%
Revenue YoY
-23.8%
0.9%
Net Profit YoY
-62.8%
EPS (diluted)
$-1.41
$0.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DNA
DNA
TRTX
TRTX
Q4 25
$33.4M
$35.0M
Q3 25
$38.8M
$37.8M
Q2 25
$49.6M
$36.2M
Q1 25
$48.3M
$37.0M
Q4 24
$43.8M
$34.7M
Q3 24
$89.0M
$40.1M
Q2 24
$56.2M
$39.3M
Q1 24
$37.9M
$38.9M
Net Profit
DNA
DNA
TRTX
TRTX
Q4 25
$4.0M
Q3 25
$-80.8M
$22.0M
Q2 25
$-60.3M
$20.6M
Q1 25
$-91.0M
$13.7M
Q4 24
$10.7M
Q3 24
$-56.4M
$22.2M
Q2 24
$-217.2M
$24.7M
Q1 24
$-165.9M
$16.7M
Operating Margin
DNA
DNA
TRTX
TRTX
Q4 25
-211.9%
11.6%
Q3 25
-231.8%
58.4%
Q2 25
-132.1%
57.3%
Q1 25
-184.1%
37.2%
Q4 24
-236.3%
30.3%
Q3 24
-62.0%
55.4%
Q2 24
-396.7%
63.1%
Q1 24
-469.1%
44.0%
Net Margin
DNA
DNA
TRTX
TRTX
Q4 25
15.6%
Q3 25
-207.9%
58.1%
Q2 25
-121.6%
57.0%
Q1 25
-188.2%
37.0%
Q4 24
43.3%
Q3 24
-63.3%
55.3%
Q2 24
-386.4%
62.9%
Q1 24
-437.3%
43.0%
EPS (diluted)
DNA
DNA
TRTX
TRTX
Q4 25
$-1.41
$0.01
Q3 25
$-1.45
$0.23
Q2 25
$-1.10
$0.21
Q1 25
$-1.68
$0.12
Q4 24
$-1.91
$0.09
Q3 24
$-1.08
$0.23
Q2 24
$-4.23
$0.26
Q1 24
$-3.32
$0.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DNA
DNA
TRTX
TRTX
Cash + ST InvestmentsLiquidity on hand
$422.6M
$87.6M
Total DebtLower is stronger
$3.3B
Stockholders' EquityBook value
$508.6M
$1.1B
Total Assets
$1.1B
$4.4B
Debt / EquityLower = less leverage
3.10×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DNA
DNA
TRTX
TRTX
Q4 25
$422.6M
$87.6M
Q3 25
$495.5M
$93.6M
Q2 25
$559.4M
$165.8M
Q1 25
$325.3M
$363.0M
Q4 24
$561.6M
$190.2M
Q3 24
$616.2M
$226.3M
Q2 24
$730.4M
$259.2M
Q1 24
$840.4M
$203.1M
Total Debt
DNA
DNA
TRTX
TRTX
Q4 25
$3.3B
Q3 25
$2.9B
Q2 25
$3.0B
Q1 25
$2.8B
Q4 24
$2.6B
Q3 24
$2.5B
Q2 24
$2.5B
Q1 24
$2.7B
Stockholders' Equity
DNA
DNA
TRTX
TRTX
Q4 25
$508.6M
$1.1B
Q3 25
$559.8M
$1.1B
Q2 25
$613.0M
$1.1B
Q1 25
$647.4M
$1.1B
Q4 24
$716.1M
$1.1B
Q3 24
$797.9M
$1.1B
Q2 24
$833.1M
$1.1B
Q1 24
$987.3M
$1.1B
Total Assets
DNA
DNA
TRTX
TRTX
Q4 25
$1.1B
$4.4B
Q3 25
$1.2B
$4.1B
Q2 25
$1.2B
$4.2B
Q1 25
$1.3B
$4.0B
Q4 24
$1.4B
$3.7B
Q3 24
$1.5B
$3.7B
Q2 24
$1.6B
$3.7B
Q1 24
$1.6B
$3.8B
Debt / Equity
DNA
DNA
TRTX
TRTX
Q4 25
3.10×
Q3 25
2.72×
Q2 25
2.78×
Q1 25
2.56×
Q4 24
2.31×
Q3 24
2.22×
Q2 24
2.25×
Q1 24
2.38×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DNA
DNA
TRTX
TRTX
Operating Cash FlowLast quarter
$-47.7M
$90.4M
Free Cash FlowOCF − Capex
$-47.7M
FCF MarginFCF / Revenue
-142.8%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
22.73×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DNA
DNA
TRTX
TRTX
Q4 25
$-47.7M
$90.4M
Q3 25
$-31.6M
$21.8M
Q2 25
$-40.3M
$24.7M
Q1 25
$-51.5M
$19.1M
Q4 24
$-42.4M
$112.1M
Q3 24
$-103.5M
$23.7M
Q2 24
$-84.4M
$25.6M
Q1 24
$-89.3M
$37.4M
Free Cash Flow
DNA
DNA
TRTX
TRTX
Q4 25
$-47.7M
Q3 25
Q2 25
$-40.3M
Q1 25
$-59.1M
Q4 24
$-56.1M
Q3 24
$-118.6M
Q2 24
$-111.4M
Q1 24
$-96.0M
FCF Margin
DNA
DNA
TRTX
TRTX
Q4 25
-142.8%
Q3 25
Q2 25
-81.2%
Q1 25
-122.4%
Q4 24
-128.0%
Q3 24
-133.2%
Q2 24
-198.2%
Q1 24
-252.9%
Capex Intensity
DNA
DNA
TRTX
TRTX
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.1%
Q1 25
15.8%
Q4 24
31.3%
Q3 24
16.9%
Q2 24
48.1%
Q1 24
17.7%
Cash Conversion
DNA
DNA
TRTX
TRTX
Q4 25
22.73×
Q3 25
0.99×
Q2 25
1.20×
Q1 25
1.39×
Q4 24
10.50×
Q3 24
1.07×
Q2 24
1.03×
Q1 24
2.23×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DNA
DNA

Cell Engineering Segment$26.0M78%
Other$7.4M22%

TRTX
TRTX

Segment breakdown not available.

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