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Side-by-side financial comparison of Dogwood Therapeutics, Inc. (DWTX) and PROTHENA CORP PUBLIC LTD CO (PRTA). Click either name above to swap in a different company.

Dogwood Therapeutics, Inc. is the larger business by last-quarter revenue ($22.8K vs $21.0K, roughly 1.1× PROTHENA CORP PUBLIC LTD CO). On growth, Dogwood Therapeutics, Inc. posted the faster year-over-year revenue change (-43.7% vs -99.0%). Over the past eight quarters, Dogwood Therapeutics, Inc.'s revenue compounded faster (117.7% CAGR vs -35.2%).

Dogwood Therapeutics, Inc. is a clinical-stage biotechnology company focused on researching and developing targeted therapies for rare kidney diseases, metabolic disorders, and other unmet medical needs. It collaborates with global healthcare and research partners to advance its pipeline of innovative treatment candidates for patient populations worldwide.

Prothena Corporation plc is a late-stage clinical biotechnology firm focused on developing and commercializing innovative antibody therapies for neurodegenerative disorders, rare diseases and immune-related conditions. Its core pipeline targets unmet medical needs including amyloidosis, Parkinson's and Alzheimer's, serving key markets across North America, Europe and the Asia-Pacific.

DWTX vs PRTA — Head-to-Head

Bigger by revenue
DWTX
DWTX
1.1× larger
DWTX
$22.8K
$21.0K
PRTA
Growing faster (revenue YoY)
DWTX
DWTX
+55.3% gap
DWTX
-43.7%
-99.0%
PRTA
Faster 2-yr revenue CAGR
DWTX
DWTX
Annualised
DWTX
117.7%
-35.2%
PRTA

Income Statement — Q1 FY2024 vs Q4 FY2025

Metric
DWTX
DWTX
PRTA
PRTA
Revenue
$22.8K
$21.0K
Net Profit
$-1.3M
Gross Margin
Operating Margin
-5772.2%
Net Margin
-5672.2%
Revenue YoY
-43.7%
-99.0%
Net Profit YoY
14.9%
62.7%
EPS (diluted)
$-1.68

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DWTX
DWTX
PRTA
PRTA
Q4 25
$21.0K
Q3 25
$2.4M
Q2 25
$4.4M
Q1 25
$2.8M
Q4 24
$2.1M
Q3 24
$970.0K
Q2 24
$132.0M
Q1 24
$22.8K
$50.0K
Net Profit
DWTX
DWTX
PRTA
PRTA
Q4 25
Q3 25
$-36.5M
Q2 25
$-125.8M
Q1 25
$-60.2M
Q4 24
Q3 24
$-59.0M
Q2 24
$66.9M
Q1 24
$-1.3M
$-72.2M
Operating Margin
DWTX
DWTX
PRTA
PRTA
Q4 25
Q3 25
-1666.3%
Q2 25
-1914.4%
Q1 25
-2319.0%
Q4 24
Q3 24
-6857.0%
Q2 24
44.2%
Q1 24
-5772.2%
-163056.0%
Net Margin
DWTX
DWTX
PRTA
PRTA
Q4 25
Q3 25
-1513.1%
Q2 25
-2845.4%
Q1 25
-2128.5%
Q4 24
Q3 24
-6082.6%
Q2 24
50.7%
Q1 24
-5672.2%
-144478.0%
EPS (diluted)
DWTX
DWTX
PRTA
PRTA
Q4 25
Q3 25
$-0.68
Q2 25
$-2.34
Q1 25
$-1.12
Q4 24
Q3 24
$-1.10
Q2 24
$1.22
Q1 24
$-1.68
$-1.34

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DWTX
DWTX
PRTA
PRTA
Cash + ST InvestmentsLiquidity on hand
$2.4M
$307.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$2.7M
$280.5M
Total Assets
$3.2M
$326.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DWTX
DWTX
PRTA
PRTA
Q4 25
$307.5M
Q3 25
$330.8M
Q2 25
$371.4M
Q1 25
$417.9M
Q4 24
$471.4M
Q3 24
$519.3M
Q2 24
$564.1M
Q1 24
$2.4M
$546.5M
Stockholders' Equity
DWTX
DWTX
PRTA
PRTA
Q4 25
$280.5M
Q3 25
$295.0M
Q2 25
$324.3M
Q1 25
$437.7M
Q4 24
$486.9M
Q3 24
$534.4M
Q2 24
$581.9M
Q1 24
$2.7M
$502.4M
Total Assets
DWTX
DWTX
PRTA
PRTA
Q4 25
$326.8M
Q3 25
$352.6M
Q2 25
$399.1M
Q1 25
$495.3M
Q4 24
$547.1M
Q3 24
$595.3M
Q2 24
$645.6M
Q1 24
$3.2M
$623.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DWTX
DWTX
PRTA
PRTA
Operating Cash FlowLast quarter
$-937.4K
$-163.6M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DWTX
DWTX
PRTA
PRTA
Q4 25
$-163.6M
Q3 25
$-40.6M
Q2 25
$-46.3M
Q1 25
$-53.4M
Q4 24
$-150.1M
Q3 24
$-45.2M
Q2 24
$16.0M
Q1 24
$-937.4K
$-73.1M
Cash Conversion
DWTX
DWTX
PRTA
PRTA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.24×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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