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Side-by-side financial comparison of ENANTA PHARMACEUTICALS INC (ENTA) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.
ENANTA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($18.6M vs $15.8M, roughly 1.2× Spire Global, Inc.). ENANTA PHARMACEUTICALS INC runs the higher net margin — -64.1% vs -176.6%, a 112.5% gap on every dollar of revenue. On growth, ENANTA PHARMACEUTICALS INC posted the faster year-over-year revenue change (9.8% vs -26.9%). ENANTA PHARMACEUTICALS INC produced more free cash flow last quarter ($-11.8M vs $-16.2M). Over the past eight quarters, ENANTA PHARMACEUTICALS INC's revenue compounded faster (4.5% CAGR vs -32.6%).
Enanta Pharmaceuticals Inc is a clinical-stage biotechnology company that develops innovative antiviral therapies for infectious diseases including hepatitis B virus, respiratory syncytial virus (RSV), and SARS-CoV-2. It operates primarily in the U.S. and global markets, partnering with pharmaceutical firms to advance its small molecule drug candidate pipeline for patients with unmet medical needs.
Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.
ENTA vs SPIR — Head-to-Head
Income Statement — Q1 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $18.6M | $15.8M |
| Net Profit | $-11.9M | $-28.0M |
| Gross Margin | — | 40.2% |
| Operating Margin | -60.5% | -164.1% |
| Net Margin | -64.1% | -176.6% |
| Revenue YoY | 9.8% | -26.9% |
| Net Profit YoY | 46.4% | 42.7% |
| EPS (diluted) | $-0.42 | $-0.85 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $18.6M | $15.8M | ||
| Q3 25 | $15.1M | $12.7M | ||
| Q2 25 | $18.3M | $19.2M | ||
| Q1 25 | $14.9M | $23.9M | ||
| Q4 24 | $17.0M | $21.7M | ||
| Q3 24 | $14.6M | $28.6M | ||
| Q2 24 | $18.0M | $25.4M | ||
| Q1 24 | $17.1M | $34.8M |
| Q4 25 | $-11.9M | $-28.0M | ||
| Q3 25 | $-18.7M | $-19.7M | ||
| Q2 25 | $-18.3M | $119.6M | ||
| Q1 25 | $-22.6M | $-20.7M | ||
| Q4 24 | $-22.3M | $-48.8M | ||
| Q3 24 | $-28.8M | $-12.5M | ||
| Q2 24 | $-22.7M | $-16.6M | ||
| Q1 24 | $-31.2M | $-25.5M |
| Q4 25 | — | 40.2% | ||
| Q3 25 | — | 36.6% | ||
| Q2 25 | — | 48.9% | ||
| Q1 25 | — | 36.8% | ||
| Q4 24 | — | 32.4% | ||
| Q3 24 | — | 44.5% | ||
| Q2 24 | — | 43.0% | ||
| Q1 24 | — | 26.5% |
| Q4 25 | -60.5% | -164.1% | ||
| Q3 25 | -121.6% | -166.1% | ||
| Q2 25 | -103.2% | -122.7% | ||
| Q1 25 | -164.3% | -106.5% | ||
| Q4 24 | -138.8% | -144.1% | ||
| Q3 24 | -204.4% | -48.0% | ||
| Q2 24 | -134.6% | -48.6% | ||
| Q1 24 | -192.1% | -34.4% |
| Q4 25 | -64.1% | -176.6% | ||
| Q3 25 | -123.6% | -155.3% | ||
| Q2 25 | -99.7% | 623.4% | ||
| Q1 25 | -151.7% | -86.5% | ||
| Q4 24 | -131.4% | -225.2% | ||
| Q3 24 | -197.3% | -43.7% | ||
| Q2 24 | -126.1% | -65.2% | ||
| Q1 24 | -182.7% | -73.3% |
| Q4 25 | $-0.42 | $-0.85 | ||
| Q3 25 | $-0.88 | $-0.61 | ||
| Q2 25 | $-0.85 | $3.72 | ||
| Q1 25 | $-1.06 | $-0.77 | ||
| Q4 24 | $-1.05 | $-1.93 | ||
| Q3 24 | $-1.36 | $-0.50 | ||
| Q2 24 | $-1.07 | $-0.68 | ||
| Q1 24 | $-1.47 | $-1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $37.4M | $81.8M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $126.6M | $112.9M |
| Total Assets | $329.5M | $211.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $37.4M | $81.8M | ||
| Q3 25 | $32.3M | $96.8M | ||
| Q2 25 | $44.8M | $117.6M | ||
| Q1 25 | $60.2M | $35.9M | ||
| Q4 24 | $84.3M | $19.2M | ||
| Q3 24 | $37.2M | $36.6M | ||
| Q2 24 | $35.8M | $45.8M | ||
| Q1 24 | $63.5M | $63.7M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | $103.7M | ||
| Q4 24 | — | $103.1M | ||
| Q3 24 | — | $4.9M | ||
| Q2 24 | — | $4.9M | ||
| Q1 24 | — | $123.1M |
| Q4 25 | $126.6M | $112.9M | ||
| Q3 25 | $64.7M | $133.1M | ||
| Q2 25 | $79.3M | $149.2M | ||
| Q1 25 | $93.5M | $3.7M | ||
| Q4 24 | $111.8M | $-11.7M | ||
| Q3 24 | $128.8M | $30.8M | ||
| Q2 24 | $148.9M | $40.3M | ||
| Q1 24 | $166.1M | $52.5M |
| Q4 25 | $329.5M | $211.0M | ||
| Q3 25 | $280.7M | $224.3M | ||
| Q2 25 | $301.0M | $239.5M | ||
| Q1 25 | $323.0M | $208.8M | ||
| Q4 24 | $348.6M | $193.6M | ||
| Q3 24 | $376.7M | $224.2M | ||
| Q2 24 | $398.8M | $230.8M | ||
| Q1 24 | $413.6M | $252.3M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 27.92× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.16× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 2.35× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-11.7M | $-4.3M |
| Free Cash FlowOCF − Capex | $-11.8M | $-16.2M |
| FCF MarginFCF / Revenue | -63.6% | -102.1% |
| Capex IntensityCapex / Revenue | 0.8% | 75.1% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-18.5M | $-92.6M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-11.7M | $-4.3M | ||
| Q3 25 | $-6.5M | $-12.0M | ||
| Q2 25 | $17.5M | $-35.1M | ||
| Q1 25 | $-13.5M | $-8.4M | ||
| Q4 24 | $-16.8M | $-19.2M | ||
| Q3 24 | $-10.4M | $14.0M | ||
| Q2 24 | $-14.8M | $-4.4M | ||
| Q1 24 | $-28.6M | $-8.8M |
| Q4 25 | $-11.8M | $-16.2M | ||
| Q3 25 | $-7.9M | $-20.4M | ||
| Q2 25 | $17.4M | $-38.7M | ||
| Q1 25 | $-16.0M | $-17.3M | ||
| Q4 24 | $-25.5M | $-24.3M | ||
| Q3 24 | $-19.4M | $5.1M | ||
| Q2 24 | $-21.3M | $-9.9M | ||
| Q1 24 | $-30.3M | $-15.9M |
| Q4 25 | -63.6% | -102.1% | ||
| Q3 25 | -52.5% | -161.3% | ||
| Q2 25 | 94.7% | -201.7% | ||
| Q1 25 | -107.4% | -72.6% | ||
| Q4 24 | -150.6% | -112.2% | ||
| Q3 24 | -132.5% | 17.8% | ||
| Q2 24 | -118.6% | -39.0% | ||
| Q1 24 | -177.5% | -45.7% |
| Q4 25 | 0.8% | 75.1% | ||
| Q3 25 | 9.6% | 66.2% | ||
| Q2 25 | 0.8% | 18.8% | ||
| Q1 25 | 17.0% | 37.3% | ||
| Q4 24 | 51.6% | 23.5% | ||
| Q3 24 | 61.3% | 31.2% | ||
| Q2 24 | 36.4% | 21.8% | ||
| Q1 24 | 9.8% | 20.3% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | -0.29× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
