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Side-by-side financial comparison of EOG Resources (EOG) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

EOG Resources is the larger business by last-quarter revenue ($5.6B vs $3.0B, roughly 1.9× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 12.4%, a 22.1% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs 0.9%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs -4.0%).

EOG Resources, Inc. is an American energy company engaged in hydrocarbon exploration. It is organized in Delaware and headquartered in the Heritage Plaza building in Houston, Texas.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

EOG vs VRTX — Head-to-Head

Bigger by revenue
EOG
EOG
1.9× larger
EOG
$5.6B
$3.0B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+6.9% gap
VRTX
7.8%
0.9%
EOG
Higher net margin
VRTX
VRTX
22.1% more per $
VRTX
34.5%
12.4%
EOG
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
-4.0%
EOG

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
EOG
EOG
VRTX
VRTX
Revenue
$5.6B
$3.0B
Net Profit
$701.0M
$1.0B
Gross Margin
86.8%
Operating Margin
16.7%
38.1%
Net Margin
12.4%
34.5%
Revenue YoY
0.9%
7.8%
Net Profit YoY
-44.0%
59.6%
EPS (diluted)
$1.31
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
EOG
EOG
VRTX
VRTX
Q1 26
$3.0B
Q4 25
$5.6B
$3.2B
Q3 25
$5.8B
$3.1B
Q2 25
$5.5B
$3.0B
Q1 25
$5.7B
$2.8B
Q4 24
$5.6B
$2.9B
Q3 24
$6.0B
$2.8B
Q2 24
$6.0B
$2.6B
Net Profit
EOG
EOG
VRTX
VRTX
Q1 26
$1.0B
Q4 25
$701.0M
$1.2B
Q3 25
$1.5B
$1.1B
Q2 25
$1.3B
$1.0B
Q1 25
$1.5B
$646.3M
Q4 24
$1.3B
$913.0M
Q3 24
$1.7B
$1.0B
Q2 24
$1.7B
$-3.6B
Gross Margin
EOG
EOG
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
EOG
EOG
VRTX
VRTX
Q1 26
38.1%
Q4 25
16.7%
37.8%
Q3 25
31.4%
38.6%
Q2 25
31.9%
38.8%
Q1 25
32.8%
22.7%
Q4 24
28.5%
35.2%
Q3 24
35.0%
40.3%
Q2 24
35.4%
-132.9%
Net Margin
EOG
EOG
VRTX
VRTX
Q1 26
34.5%
Q4 25
12.4%
37.3%
Q3 25
25.2%
35.2%
Q2 25
24.6%
34.8%
Q1 25
25.8%
23.3%
Q4 24
22.4%
31.4%
Q3 24
28.0%
37.7%
Q2 24
28.0%
-135.8%
EPS (diluted)
EOG
EOG
VRTX
VRTX
Q1 26
$4.02
Q4 25
$1.31
$4.64
Q3 25
$2.70
$4.20
Q2 25
$2.46
$3.99
Q1 25
$2.65
$2.49
Q4 24
$2.25
$3.62
Q3 24
$2.95
$4.01
Q2 24
$2.95
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
EOG
EOG
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$3.4B
Total DebtLower is stronger
Stockholders' EquityBook value
$29.8B
$19.4B
Total Assets
$51.8B
$26.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
$3.4B
$6.6B
Q3 25
$3.5B
$6.3B
Q2 25
$5.2B
$6.4B
Q1 25
$6.6B
$6.2B
Q4 24
$7.1B
$6.1B
Q3 24
$6.1B
$6.5B
Q2 24
$5.4B
$5.8B
Stockholders' Equity
EOG
EOG
VRTX
VRTX
Q1 26
$19.4B
Q4 25
$29.8B
$18.7B
Q3 25
$30.3B
$17.3B
Q2 25
$29.2B
$17.2B
Q1 25
$29.5B
$16.5B
Q4 24
$29.4B
$16.4B
Q3 24
$29.6B
$15.6B
Q2 24
$29.2B
$14.8B
Total Assets
EOG
EOG
VRTX
VRTX
Q1 26
$26.5B
Q4 25
$51.8B
$25.6B
Q3 25
$52.2B
$24.9B
Q2 25
$46.3B
$24.0B
Q1 25
$47.0B
$22.9B
Q4 24
$47.2B
$22.5B
Q3 24
$46.2B
$22.2B
Q2 24
$45.2B
$20.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
EOG
EOG
VRTX
VRTX
Operating Cash FlowLast quarter
$2.6B
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
3.73×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
$2.6B
$498.0M
Q3 25
$3.1B
$1.2B
Q2 25
$2.0B
$1.1B
Q1 25
$2.3B
$818.9M
Q4 24
$2.8B
$584.6M
Q3 24
$3.6B
$1.4B
Q2 24
$2.9B
$-3.8B
Free Cash Flow
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$778.2M
Q4 24
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
FCF Margin
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
28.1%
Q4 24
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Capex Intensity
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
1.5%
Q4 24
3.2%
Q3 24
2.4%
Q2 24
2.6%
Cash Conversion
EOG
EOG
VRTX
VRTX
Q1 26
Q4 25
3.73×
0.42×
Q3 25
2.11×
1.15×
Q2 25
1.51×
1.04×
Q1 25
1.56×
1.27×
Q4 24
2.21×
0.64×
Q3 24
2.14×
1.31×
Q2 24
1.71×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

EOG
EOG

Oil And Condensate$3.0B53%
Natural Gas Gathering Transportation Marketing And Processing$1.1B20%
Natural Gas Production$847.0M15%
Natural Gas Liquids Reserves$666.0M12%
Other Net$20.0M0%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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