vs

Side-by-side financial comparison of Empire State Realty Trust, Inc. (ESRT) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

Empire State Realty Trust, Inc. is the larger business by last-quarter revenue ($190.3M vs $103.7M, roughly 1.8× Twist Bioscience Corp). Empire State Realty Trust, Inc. runs the higher net margin — 1.6% vs -29.4%, a 31.0% gap on every dollar of revenue. On growth, Twist Bioscience Corp posted the faster year-over-year revenue change (16.9% vs 5.7%).

Empire State Realty Trust is a leading real estate investment trust that owns, manages, and operates a portfolio of premium commercial, residential, and retail properties primarily in the New York City metropolitan area, including the iconic Empire State Building. It serves corporate tenants, retail partners, and residential occupants, focusing on sustainable property operations and long-term asset value growth.

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

ESRT vs TWST — Head-to-Head

Bigger by revenue
ESRT
ESRT
1.8× larger
ESRT
$190.3M
$103.7M
TWST
Growing faster (revenue YoY)
TWST
TWST
+11.2% gap
TWST
16.9%
5.7%
ESRT
Higher net margin
ESRT
ESRT
31.0% more per $
ESRT
1.6%
-29.4%
TWST

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
ESRT
ESRT
TWST
TWST
Revenue
$190.3M
$103.7M
Net Profit
$3.0M
$-30.5M
Gross Margin
52.0%
Operating Margin
15.5%
-31.7%
Net Margin
1.6%
-29.4%
Revenue YoY
5.7%
16.9%
Net Profit YoY
-73.7%
3.4%
EPS (diluted)
$0.20
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESRT
ESRT
TWST
TWST
Q1 26
$190.3M
Q4 25
$199.2M
$103.7M
Q3 25
$197.7M
Q2 25
$191.3M
Q1 25
$180.1M
Q4 24
$197.6M
Q3 24
$199.6M
Q2 24
$189.5M
Net Profit
ESRT
ESRT
TWST
TWST
Q1 26
$3.0M
Q4 25
$32.2M
$-30.5M
Q3 25
$13.6M
Q2 25
$11.4M
Q1 25
$15.8M
Q4 24
$18.8M
Q3 24
$22.8M
Q2 24
$28.6M
Gross Margin
ESRT
ESRT
TWST
TWST
Q1 26
Q4 25
52.0%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Operating Margin
ESRT
ESRT
TWST
TWST
Q1 26
15.5%
Q4 25
17.8%
-31.7%
Q3 25
19.9%
Q2 25
18.4%
Q1 25
14.3%
Q4 24
21.7%
Q3 24
22.7%
Q2 24
20.8%
Net Margin
ESRT
ESRT
TWST
TWST
Q1 26
1.6%
Q4 25
16.1%
-29.4%
Q3 25
6.9%
Q2 25
6.0%
Q1 25
8.8%
Q4 24
9.5%
Q3 24
11.4%
Q2 24
15.1%
EPS (diluted)
ESRT
ESRT
TWST
TWST
Q1 26
$0.20
Q4 25
$0.11
$-0.50
Q3 25
$0.05
Q2 25
$0.04
Q1 25
$0.05
Q4 24
$0.07
Q3 24
$0.08
Q2 24
$0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESRT
ESRT
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$68.8M
$197.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.8B
$456.1M
Total Assets
$4.4B
$638.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESRT
ESRT
TWST
TWST
Q1 26
$68.8M
Q4 25
$132.7M
$197.9M
Q3 25
$154.1M
Q2 25
$94.6M
Q1 25
$187.8M
Q4 24
$385.5M
Q3 24
$421.9M
Q2 24
$535.5M
Stockholders' Equity
ESRT
ESRT
TWST
TWST
Q1 26
$1.8B
Q4 25
$1.1B
$456.1M
Q3 25
$1.0B
Q2 25
$1.0B
Q1 25
$1.0B
Q4 24
$1.0B
Q3 24
$1.0B
Q2 24
$1.0B
Total Assets
ESRT
ESRT
TWST
TWST
Q1 26
$4.4B
Q4 25
$4.5B
$638.1M
Q3 25
$4.1B
Q2 25
$4.1B
Q1 25
$4.1B
Q4 24
$4.5B
Q3 24
$4.4B
Q2 24
$4.4B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESRT
ESRT
TWST
TWST
Operating Cash FlowLast quarter
$-24.8M
Free Cash FlowOCF − Capex
$-34.8M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
10.0%
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESRT
ESRT
TWST
TWST
Q1 26
Q4 25
$249.1M
$-24.8M
Q3 25
$105.3M
Q2 25
$26.7M
Q1 25
$83.1M
Q4 24
$260.9M
Q3 24
$102.8M
Q2 24
$37.1M
Free Cash Flow
ESRT
ESRT
TWST
TWST
Q1 26
Q4 25
$50.6M
$-34.8M
Q3 25
$72.8M
Q2 25
$-55.1M
Q1 25
$41.1M
Q4 24
$88.0M
Q3 24
$-65.1M
Q2 24
$19.5M
FCF Margin
ESRT
ESRT
TWST
TWST
Q1 26
Q4 25
25.4%
-33.5%
Q3 25
36.8%
Q2 25
-28.8%
Q1 25
22.8%
Q4 24
44.5%
Q3 24
-32.6%
Q2 24
10.3%
Capex Intensity
ESRT
ESRT
TWST
TWST
Q1 26
10.0%
Q4 25
99.6%
9.6%
Q3 25
16.5%
Q2 25
42.8%
Q1 25
23.4%
Q4 24
87.5%
Q3 24
84.1%
Q2 24
9.3%
Cash Conversion
ESRT
ESRT
TWST
TWST
Q1 26
Q4 25
7.74×
Q3 25
7.72×
Q2 25
2.35×
Q1 25
5.27×
Q4 24
13.88×
Q3 24
4.51×
Q2 24
1.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESRT
ESRT

Rental revenue (1)$166.1M87%
Observatory revenue$18.5M10%
Other revenue and fees$4.1M2%
Lease termination fees$1.4M1%
Third-party management and other fees$277.0K0%

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

Related Comparisons