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Side-by-side financial comparison of EXELIXIS, INC. (EXEL) and Hilltop Holdings Inc. (HTH). Click either name above to swap in a different company.

EXELIXIS, INC. is the larger business by last-quarter revenue ($598.7M vs $300.5M, roughly 2.0× Hilltop Holdings Inc.). EXELIXIS, INC. runs the higher net margin — 40.8% vs 13.0%, a 27.9% gap on every dollar of revenue. Over the past eight quarters, EXELIXIS, INC.'s revenue compounded faster (18.7% CAGR vs 0.6%).

Exelixis, Inc. is a genomics-based drug discovery company located in Alameda, California, and the producer of Cometriq, a treatment approved by the U.S. Food and Drug Administration (FDA) for medullary thyroid cancer with clinical activity in several other types of metastatic cancer.

Hilltop Holdings Inc. is a financial holding company based in Dallas, Texas. It offers financial products and banking services through three primary subsidiaries: PlainsCapital Bank, PrimeLending, and HilltopSecurities.

EXEL vs HTH — Head-to-Head

Bigger by revenue
EXEL
EXEL
2.0× larger
EXEL
$598.7M
$300.5M
HTH
Higher net margin
EXEL
EXEL
27.9% more per $
EXEL
40.8%
13.0%
HTH
Faster 2-yr revenue CAGR
EXEL
EXEL
Annualised
EXEL
18.7%
0.6%
HTH

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
EXEL
EXEL
HTH
HTH
Revenue
$598.7M
$300.5M
Net Profit
$244.5M
$39.0M
Gross Margin
95.6%
Operating Margin
39.3%
Net Margin
40.8%
13.0%
Revenue YoY
5.6%
Net Profit YoY
74.8%
-12.4%
EPS (diluted)
$0.89
$0.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
EXEL
EXEL
HTH
HTH
Q1 26
$598.7M
$300.5M
Q4 25
$597.8M
$329.9M
Q3 25
$568.3M
$330.2M
Q2 25
$555.4M
$303.3M
Q1 25
$566.8M
$318.5M
Q4 24
$301.1M
Q3 24
$539.5M
$305.5M
Q2 24
$637.2M
$297.0M
Net Profit
EXEL
EXEL
HTH
HTH
Q1 26
$244.5M
$39.0M
Q4 25
$193.6M
$41.6M
Q3 25
$184.8M
$45.8M
Q2 25
$159.6M
$36.1M
Q1 25
$139.9M
$42.1M
Q4 24
$35.5M
Q3 24
$118.0M
$29.7M
Q2 24
$226.1M
$20.3M
Gross Margin
EXEL
EXEL
HTH
HTH
Q1 26
95.6%
Q4 25
96.9%
Q3 25
96.6%
Q2 25
96.5%
Q1 25
96.5%
Q4 24
Q3 24
96.8%
Q2 24
97.2%
Operating Margin
EXEL
EXEL
HTH
HTH
Q1 26
39.3%
Q4 25
39.6%
16.1%
Q3 25
37.6%
18.4%
Q2 25
33.6%
16.3%
Q1 25
28.8%
18.1%
Q4 24
14.7%
Q3 24
25.2%
13.9%
Q2 24
43.3%
10.0%
Net Margin
EXEL
EXEL
HTH
HTH
Q1 26
40.8%
13.0%
Q4 25
32.4%
12.6%
Q3 25
32.5%
13.9%
Q2 25
28.7%
11.9%
Q1 25
24.7%
13.2%
Q4 24
11.8%
Q3 24
21.9%
9.7%
Q2 24
35.5%
6.8%
EPS (diluted)
EXEL
EXEL
HTH
HTH
Q1 26
$0.89
$0.64
Q4 25
$0.69
$0.68
Q3 25
$0.65
$0.74
Q2 25
$0.55
$0.57
Q1 25
$0.47
$0.65
Q4 24
$0.55
Q3 24
$0.40
$0.46
Q2 24
$0.77
$0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
EXEL
EXEL
HTH
HTH
Cash + ST InvestmentsLiquidity on hand
$1.1B
Total DebtLower is stronger
$990.8M
Stockholders' EquityBook value
$2.2B
$2.2B
Total Assets
$2.8B
$15.7B
Debt / EquityLower = less leverage
0.46×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
EXEL
EXEL
HTH
HTH
Q1 26
$1.1B
Q4 25
$988.5M
Q3 25
$791.1M
Q2 25
$1.0B
Q1 25
$1.1B
Q4 24
Q3 24
$1.2B
Q2 24
$1.0B
Total Debt
EXEL
EXEL
HTH
HTH
Q1 26
$990.8M
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Stockholders' Equity
EXEL
EXEL
HTH
HTH
Q1 26
$2.2B
$2.2B
Q4 25
$2.2B
$2.2B
Q3 25
$2.0B
$2.2B
Q2 25
$2.1B
$2.2B
Q1 25
$2.2B
$2.2B
Q4 24
$2.2B
Q3 24
$2.3B
$2.2B
Q2 24
$2.1B
$2.1B
Total Assets
EXEL
EXEL
HTH
HTH
Q1 26
$2.8B
$15.7B
Q4 25
$2.8B
$15.8B
Q3 25
$2.7B
$15.6B
Q2 25
$2.8B
$15.4B
Q1 25
$2.9B
$15.8B
Q4 24
$16.3B
Q3 24
$3.0B
$15.9B
Q2 24
$2.8B
$15.6B
Debt / Equity
EXEL
EXEL
HTH
HTH
Q1 26
0.46×
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
EXEL
EXEL
HTH
HTH
Operating Cash FlowLast quarter
$333.5M
Free Cash FlowOCF − Capex
$332.4M
FCF MarginFCF / Revenue
55.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
1.36×
TTM Free Cash FlowTrailing 4 quarters
$875.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
EXEL
EXEL
HTH
HTH
Q1 26
$333.5M
Q4 25
$290.3M
$-38.7M
Q3 25
$49.0M
$273.0M
Q2 25
$211.4M
$-234.6M
Q1 25
$240.3M
$5.8M
Q4 24
$273.9M
Q3 24
$271.3M
$515.6M
Q2 24
$119.5M
$-435.3M
Free Cash Flow
EXEL
EXEL
HTH
HTH
Q1 26
$332.4M
Q4 25
$288.8M
$-55.5M
Q3 25
$46.2M
$271.0M
Q2 25
$208.5M
$-234.6M
Q1 25
$236.3M
$5.0M
Q4 24
$266.8M
Q3 24
$263.1M
$513.8M
Q2 24
$113.0M
$-437.3M
FCF Margin
EXEL
EXEL
HTH
HTH
Q1 26
55.5%
Q4 25
48.3%
-16.8%
Q3 25
8.1%
82.1%
Q2 25
37.5%
-77.4%
Q1 25
41.7%
1.6%
Q4 24
88.6%
Q3 24
48.8%
168.2%
Q2 24
17.7%
-147.2%
Capex Intensity
EXEL
EXEL
HTH
HTH
Q1 26
0.2%
Q4 25
0.2%
5.1%
Q3 25
0.5%
0.6%
Q2 25
0.5%
0.0%
Q1 25
0.7%
0.3%
Q4 24
2.4%
Q3 24
1.5%
0.6%
Q2 24
1.0%
0.7%
Cash Conversion
EXEL
EXEL
HTH
HTH
Q1 26
1.36×
Q4 25
1.50×
-0.93×
Q3 25
0.27×
5.96×
Q2 25
1.32×
-6.50×
Q1 25
1.72×
0.14×
Q4 24
7.71×
Q3 24
2.30×
17.36×
Q2 24
0.53×
-21.41×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

EXEL
EXEL

Cabometyx$544.7M91%
Collaboration$52.1M9%
Collaborative Arrangementwith Takeda$5.9M1%
Cometriq$1.8M0%

HTH
HTH

Noninterest Income$188.4M63%
Net Interest Income$112.1M37%

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