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Side-by-side financial comparison of FATE THERAPEUTICS INC (FATE) and Senti Biosciences, Inc. (SNTI). Click either name above to swap in a different company.

Senti Biosciences, Inc. is the larger business by last-quarter revenue ($1.8M vs $1.4M, roughly 1.3× FATE THERAPEUTICS INC). Senti Biosciences, Inc. produced more free cash flow last quarter ($-13.3M vs $-112.0M). Over the past eight quarters, Senti Biosciences, Inc.'s revenue compounded faster (165.2% CAGR vs -15.7%).

Insys Therapeutics was an American specialty pharmaceutical company based in Chandler, Arizona in 1990. Its main product was Subsys, a sublingual liquid form of the drug fentanyl. Fentanyl is an extremely fast-acting and powerful opioid used to relieve breakthrough pain in cancer patients, and prescription of fentanyl in the US for such pain usually requires documented failure of more conservative therapies.

Senti Biosciences, Inc. is a clinical-stage biotechnology company specializing in synthetic biology and gene circuit engineering to develop next-generation programmable cell and gene therapies. Its core pipeline targets oncology and autoimmune diseases, serving global biopharmaceutical markets and partnering with leading industry players to advance targeted treatments for underserved patient groups.

FATE vs SNTI — Head-to-Head

Bigger by revenue
SNTI
SNTI
1.3× larger
SNTI
$1.8M
$1.4M
FATE
More free cash flow
SNTI
SNTI
$98.8M more FCF
SNTI
$-13.3M
$-112.0M
FATE
Faster 2-yr revenue CAGR
SNTI
SNTI
Annualised
SNTI
165.2%
-15.7%
FATE

Income Statement — Q4 FY2025 vs Q2 FY2025

Metric
FATE
FATE
SNTI
SNTI
Revenue
$1.4M
$1.8M
Net Profit
$-14.7M
Gross Margin
Operating Margin
-936.3%
Net Margin
-821.2%
Revenue YoY
-26.4%
Net Profit YoY
37.9%
-31.5%
EPS (diluted)
$-0.56

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FATE
FATE
SNTI
SNTI
Q4 25
$1.4M
Q3 25
$1.7M
Q2 25
$1.9M
$1.8M
Q1 25
$1.6M
$1.9M
Q4 24
$1.9M
$0
Q3 24
$3.1M
$0
Q2 24
$6.8M
$0
Q1 24
$1.9M
$0
Net Profit
FATE
FATE
SNTI
SNTI
Q4 25
Q3 25
$-32.3M
Q2 25
$-34.1M
$-14.7M
Q1 25
$-37.6M
$-14.1M
Q4 24
$-610.0K
Q3 24
$-47.7M
$-28.9M
Q2 24
$-38.4M
$-11.2M
Q1 24
$-48.0M
$-12.1M
Operating Margin
FATE
FATE
SNTI
SNTI
Q4 25
Q3 25
-1995.1%
Q2 25
-1938.5%
-936.3%
Q1 25
-2534.1%
-867.1%
Q4 24
Q3 24
-1703.9%
Q2 24
-665.7%
Q1 24
-2652.9%
Net Margin
FATE
FATE
SNTI
SNTI
Q4 25
Q3 25
-1852.4%
Q2 25
-1786.6%
-821.2%
Q1 25
-2309.5%
-746.3%
Q4 24
Q3 24
-1551.0%
Q2 24
-567.4%
Q1 24
-2493.7%
EPS (diluted)
FATE
FATE
SNTI
SNTI
Q4 25
Q3 25
$-0.27
Q2 25
$-0.29
$-0.56
Q1 25
$-0.32
$-1.41
Q4 24
$-0.62
Q3 24
$-0.40
$-6.31
Q2 24
$-0.33
$-2.45
Q1 24
$-0.47
$-2.65

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FATE
FATE
SNTI
SNTI
Cash + ST InvestmentsLiquidity on hand
$203.7M
$21.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$207.2M
$24.7M
Total Assets
$318.9M
$68.5M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FATE
FATE
SNTI
SNTI
Q4 25
$203.7M
Q3 25
$215.4M
Q2 25
$222.8M
$21.6M
Q1 25
$240.4M
$33.8M
Q4 24
$279.1M
$48.3M
Q3 24
$296.9M
$10.5M
Q2 24
$304.9M
$15.9M
Q1 24
$121.3M
$23.7M
Stockholders' Equity
FATE
FATE
SNTI
SNTI
Q4 25
$207.2M
Q3 25
$234.1M
Q2 25
$261.4M
$24.7M
Q1 25
$288.4M
$37.9M
Q4 24
$318.7M
$25.6M
Q3 24
$362.3M
$16.0M
Q2 24
$397.0M
$44.1M
Q1 24
$426.1M
$56.1M
Total Assets
FATE
FATE
SNTI
SNTI
Q4 25
$318.9M
Q3 25
$343.7M
Q2 25
$371.6M
$68.5M
Q1 25
$398.7M
$82.8M
Q4 24
$440.7M
$97.8M
Q3 24
$495.0M
$57.7M
Q2 24
$528.8M
$86.9M
Q1 24
$569.9M
$102.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FATE
FATE
SNTI
SNTI
Operating Cash FlowLast quarter
$-106.1M
$-13.1M
Free Cash FlowOCF − Capex
$-112.0M
$-13.3M
FCF MarginFCF / Revenue
-8183.9%
-739.6%
Capex IntensityCapex / Revenue
434.8%
10.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-199.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FATE
FATE
SNTI
SNTI
Q4 25
$-106.1M
Q3 25
$-24.4M
Q2 25
$-24.6M
$-13.1M
Q1 25
$-33.8M
$-14.1M
Q4 24
$-122.9M
$-13.5M
Q3 24
$-29.4M
$-7.9M
Q2 24
$-32.3M
$-8.3M
Q1 24
$-33.4M
$-11.7M
Free Cash Flow
FATE
FATE
SNTI
SNTI
Q4 25
$-112.0M
Q3 25
$-26.6M
Q2 25
$-25.9M
$-13.3M
Q1 25
$-35.0M
Q4 24
$-123.6M
$-13.5M
Q3 24
$-29.9M
Q2 24
$-32.4M
Q1 24
$-33.4M
$-11.7M
FCF Margin
FATE
FATE
SNTI
SNTI
Q4 25
-8183.9%
Q3 25
-1526.5%
Q2 25
-1360.7%
-739.6%
Q1 25
-2148.9%
Q4 24
-6645.4%
Q3 24
-973.1%
Q2 24
-477.8%
Q1 24
-1736.9%
Capex Intensity
FATE
FATE
SNTI
SNTI
Q4 25
434.8%
Q3 25
126.5%
Q2 25
71.4%
10.9%
Q1 25
73.4%
0.0%
Q4 24
39.2%
Q3 24
16.1%
Q2 24
0.8%
Q1 24
4.5%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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