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Side-by-side financial comparison of FENNEC PHARMACEUTICALS INC. (FENC) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.

Spire Global, Inc. is the larger business by last-quarter revenue ($15.8M vs $13.8M, roughly 1.1× FENNEC PHARMACEUTICALS INC.). FENNEC PHARMACEUTICALS INC. runs the higher net margin — -34.7% vs -176.6%, a 141.9% gap on every dollar of revenue. On growth, FENNEC PHARMACEUTICALS INC. posted the faster year-over-year revenue change (73.8% vs -26.9%). Over the past eight quarters, FENNEC PHARMACEUTICALS INC.'s revenue compounded faster (-26.3% CAGR vs -32.6%).

Fennec Pharmaceuticals Inc. is a biopharmaceutical firm focused on developing and commercializing therapies to reduce treatment-related side effects in pediatric cancer patients. Its lead product targets chemotherapy-induced ototoxicity, with core North American markets serving oncology providers and vulnerable pediatric patient groups.

Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.

FENC vs SPIR — Head-to-Head

Bigger by revenue
SPIR
SPIR
1.1× larger
SPIR
$15.8M
$13.8M
FENC
Growing faster (revenue YoY)
FENC
FENC
+100.8% gap
FENC
73.8%
-26.9%
SPIR
Higher net margin
FENC
FENC
141.9% more per $
FENC
-34.7%
-176.6%
SPIR
Faster 2-yr revenue CAGR
FENC
FENC
Annualised
FENC
-26.3%
-32.6%
SPIR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FENC
FENC
SPIR
SPIR
Revenue
$13.8M
$15.8M
Net Profit
$-4.8M
$-28.0M
Gross Margin
40.2%
Operating Margin
-18.5%
-164.1%
Net Margin
-34.7%
-176.6%
Revenue YoY
73.8%
-26.9%
Net Profit YoY
-141.1%
42.7%
EPS (diluted)
$-0.17
$-0.85

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FENC
FENC
SPIR
SPIR
Q4 25
$13.8M
$15.8M
Q3 25
$12.5M
$12.7M
Q2 25
$9.7M
$19.2M
Q1 25
$8.8M
$23.9M
Q4 24
$7.9M
$21.7M
Q3 24
$7.0M
$28.6M
Q2 24
$7.3M
$25.4M
Q1 24
$25.4M
$34.8M
Net Profit
FENC
FENC
SPIR
SPIR
Q4 25
$-4.8M
$-28.0M
Q3 25
$-638.0K
$-19.7M
Q2 25
$-3.2M
$119.6M
Q1 25
$-1.2M
$-20.7M
Q4 24
$-2.0M
$-48.8M
Q3 24
$-5.7M
$-12.5M
Q2 24
$-5.6M
$-16.6M
Q1 24
$12.8M
$-25.5M
Gross Margin
FENC
FENC
SPIR
SPIR
Q4 25
40.2%
Q3 25
36.6%
Q2 25
48.9%
Q1 25
36.8%
Q4 24
32.4%
Q3 24
44.5%
Q2 24
43.0%
Q1 24
26.5%
Operating Margin
FENC
FENC
SPIR
SPIR
Q4 25
-18.5%
-164.1%
Q3 25
-1.5%
-166.1%
Q2 25
-28.3%
-122.7%
Q1 25
-9.2%
-106.5%
Q4 24
-11.8%
-144.1%
Q3 24
-74.6%
-48.0%
Q2 24
-69.4%
-48.6%
Q1 24
54.2%
-34.4%
Net Margin
FENC
FENC
SPIR
SPIR
Q4 25
-34.7%
-176.6%
Q3 25
-5.1%
-155.3%
Q2 25
-32.7%
623.4%
Q1 25
-13.3%
-86.5%
Q4 24
-25.0%
-225.2%
Q3 24
-82.2%
-43.7%
Q2 24
-76.5%
-65.2%
Q1 24
50.6%
-73.3%
EPS (diluted)
FENC
FENC
SPIR
SPIR
Q4 25
$-0.17
$-0.85
Q3 25
$-0.02
$-0.61
Q2 25
$-0.11
$3.72
Q1 25
$-0.04
$-0.77
Q4 24
$-0.02
$-1.93
Q3 24
$-0.21
$-0.50
Q2 24
$-0.20
$-0.68
Q1 24
$0.41
$-1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FENC
FENC
SPIR
SPIR
Cash + ST InvestmentsLiquidity on hand
$36.8M
$81.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$35.5M
$112.9M
Total Assets
$70.6M
$211.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FENC
FENC
SPIR
SPIR
Q4 25
$36.8M
$81.8M
Q3 25
$21.9M
$96.8M
Q2 25
$18.7M
$117.6M
Q1 25
$22.7M
$35.9M
Q4 24
$26.6M
$19.2M
Q3 24
$40.3M
$36.6M
Q2 24
$43.1M
$45.8M
Q1 24
$51.2M
$63.7M
Total Debt
FENC
FENC
SPIR
SPIR
Q4 25
Q3 25
$19.4M
Q2 25
$19.4M
Q1 25
$19.4M
$103.7M
Q4 24
$19.3M
$103.1M
Q3 24
$32.1M
$4.9M
Q2 24
$31.8M
$4.9M
Q1 24
$31.3M
$123.1M
Stockholders' Equity
FENC
FENC
SPIR
SPIR
Q4 25
$35.5M
$112.9M
Q3 25
$-4.5M
$133.1M
Q2 25
$-7.5M
$149.2M
Q1 25
$-5.9M
$3.7M
Q4 24
$-5.9M
$-11.7M
Q3 24
$-5.2M
$30.8M
Q2 24
$-1.4M
$40.3M
Q1 24
$3.0M
$52.5M
Total Assets
FENC
FENC
SPIR
SPIR
Q4 25
$70.6M
$211.0M
Q3 25
$49.3M
$224.3M
Q2 25
$44.9M
$239.5M
Q1 25
$46.4M
$208.8M
Q4 24
$44.9M
$193.6M
Q3 24
$58.9M
$224.2M
Q2 24
$63.2M
$230.8M
Q1 24
$69.2M
$252.3M
Debt / Equity
FENC
FENC
SPIR
SPIR
Q4 25
Q3 25
Q2 25
Q1 25
27.92×
Q4 24
Q3 24
0.16×
Q2 24
0.12×
Q1 24
10.40×
2.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FENC
FENC
SPIR
SPIR
Operating Cash FlowLast quarter
$-6.0M
$-4.3M
Free Cash FlowOCF − Capex
$-16.2M
FCF MarginFCF / Revenue
-102.1%
Capex IntensityCapex / Revenue
75.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-92.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FENC
FENC
SPIR
SPIR
Q4 25
$-6.0M
$-4.3M
Q3 25
$1.5M
$-12.0M
Q2 25
$-3.7M
$-35.1M
Q1 25
$-4.3M
$-8.4M
Q4 24
$-1.5M
$-19.2M
Q3 24
$-2.2M
$14.0M
Q2 24
$-8.4M
$-4.4M
Q1 24
$39.0M
$-8.8M
Free Cash Flow
FENC
FENC
SPIR
SPIR
Q4 25
$-16.2M
Q3 25
$-20.4M
Q2 25
$-38.7M
Q1 25
$-17.3M
Q4 24
$-24.3M
Q3 24
$5.1M
Q2 24
$-9.9M
Q1 24
$-15.9M
FCF Margin
FENC
FENC
SPIR
SPIR
Q4 25
-102.1%
Q3 25
-161.3%
Q2 25
-201.7%
Q1 25
-72.6%
Q4 24
-112.2%
Q3 24
17.8%
Q2 24
-39.0%
Q1 24
-45.7%
Capex Intensity
FENC
FENC
SPIR
SPIR
Q4 25
75.1%
Q3 25
66.2%
Q2 25
18.8%
Q1 25
37.3%
Q4 24
23.5%
Q3 24
31.2%
Q2 24
21.8%
Q1 24
20.3%
Cash Conversion
FENC
FENC
SPIR
SPIR
Q4 25
Q3 25
Q2 25
-0.29×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
3.04×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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