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Side-by-side financial comparison of F&G Annuities & Life, Inc. (FG) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $1.8B, roughly 1.8× F&G Annuities & Life, Inc.). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 7.3%, a 30.1% gap on every dollar of revenue. On growth, F&G Annuities & Life, Inc. posted the faster year-over-year revenue change (13.2% vs 9.5%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 6.1%).

F&G Annuities & Life, Inc. is a public company headquartered in Des Moines, Iowa. It primarily provides annuities, life insurance, and pension buyout services. The company was founded in 1959.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

FG vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.8× larger
VRTX
$3.2B
$1.8B
FG
Growing faster (revenue YoY)
FG
FG
+3.7% gap
FG
13.2%
9.5%
VRTX
Higher net margin
VRTX
VRTX
30.1% more per $
VRTX
37.3%
7.3%
FG
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
6.1%
FG

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FG
FG
VRTX
VRTX
Revenue
$1.8B
$3.2B
Net Profit
$128.0M
$1.2B
Gross Margin
85.4%
Operating Margin
37.8%
Net Margin
7.3%
37.3%
Revenue YoY
13.2%
9.5%
Net Profit YoY
-60.9%
30.5%
EPS (diluted)
$0.97
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FG
FG
VRTX
VRTX
Q4 25
$1.8B
$3.2B
Q3 25
$1.7B
$3.1B
Q2 25
$1.4B
$3.0B
Q1 25
$908.0M
$2.8B
Q4 24
$1.6B
$2.9B
Q3 24
$1.4B
$2.8B
Q2 24
$1.2B
$2.6B
Q1 24
$1.6B
$2.7B
Net Profit
FG
FG
VRTX
VRTX
Q4 25
$128.0M
$1.2B
Q3 25
$118.0M
$1.1B
Q2 25
$40.0M
$1.0B
Q1 25
$-21.0M
$646.3M
Q4 24
$327.0M
$913.0M
Q3 24
$-6.0M
$1.0B
Q2 24
$203.0M
$-3.6B
Q1 24
$115.0M
$1.1B
Gross Margin
FG
FG
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Q1 24
87.3%
Operating Margin
FG
FG
VRTX
VRTX
Q4 25
37.8%
Q3 25
38.6%
Q2 25
38.8%
Q1 25
22.7%
Q4 24
35.2%
Q3 24
40.3%
Q2 24
-132.9%
Q1 24
42.4%
Net Margin
FG
FG
VRTX
VRTX
Q4 25
7.3%
37.3%
Q3 25
7.0%
35.2%
Q2 25
2.9%
34.8%
Q1 25
-2.3%
23.3%
Q4 24
21.0%
31.4%
Q3 24
-0.4%
37.7%
Q2 24
17.3%
-135.8%
Q1 24
7.3%
40.9%
EPS (diluted)
FG
FG
VRTX
VRTX
Q4 25
$0.97
$4.64
Q3 25
$0.85
$4.20
Q2 25
$0.26
$3.99
Q1 25
$-0.20
$2.49
Q4 24
$2.53
$3.62
Q3 24
$-0.08
$4.01
Q2 24
$1.55
$-13.92
Q1 24
$0.88
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FG
FG
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.5B
$6.6B
Total DebtLower is stronger
$2.2B
Stockholders' EquityBook value
$4.8B
$18.7B
Total Assets
$98.4B
$25.6B
Debt / EquityLower = less leverage
0.47×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FG
FG
VRTX
VRTX
Q4 25
$1.5B
$6.6B
Q3 25
$2.2B
$6.3B
Q2 25
$1.9B
$6.4B
Q1 25
$3.3B
$6.2B
Q4 24
$2.3B
$6.1B
Q3 24
$3.5B
$6.5B
Q2 24
$3.5B
$5.8B
Q1 24
$2.4B
$10.2B
Total Debt
FG
FG
VRTX
VRTX
Q4 25
$2.2B
Q3 25
$2.2B
Q2 25
$2.2B
Q1 25
$2.2B
Q4 24
$2.2B
Q3 24
$2.0B
Q2 24
$2.0B
Q1 24
$1.7B
Stockholders' Equity
FG
FG
VRTX
VRTX
Q4 25
$4.8B
$18.7B
Q3 25
$4.8B
$17.3B
Q2 25
$4.4B
$17.2B
Q1 25
$4.4B
$16.5B
Q4 24
$4.0B
$16.4B
Q3 24
$4.3B
$15.6B
Q2 24
$3.7B
$14.8B
Q1 24
$3.5B
$18.5B
Total Assets
FG
FG
VRTX
VRTX
Q4 25
$98.4B
$25.6B
Q3 25
$96.1B
$24.9B
Q2 25
$91.8B
$24.0B
Q1 25
$88.0B
$22.9B
Q4 24
$85.0B
$22.5B
Q3 24
$84.1B
$22.2B
Q2 24
$78.5B
$20.1B
Q1 24
$74.4B
$23.9B
Debt / Equity
FG
FG
VRTX
VRTX
Q4 25
0.47×
Q3 25
0.46×
Q2 25
0.50×
Q1 25
0.51×
Q4 24
0.55×
Q3 24
0.47×
Q2 24
0.56×
Q1 24
0.49×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FG
FG
VRTX
VRTX
Operating Cash FlowLast quarter
$1.2B
$498.0M
Free Cash FlowOCF − Capex
$348.6M
FCF MarginFCF / Revenue
10.9%
Capex IntensityCapex / Revenue
4.7%
Cash ConversionOCF / Net Profit
9.13×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FG
FG
VRTX
VRTX
Q4 25
$1.2B
$498.0M
Q3 25
$937.0M
$1.2B
Q2 25
$1.6B
$1.1B
Q1 25
$956.0M
$818.9M
Q4 24
$1.3B
$584.6M
Q3 24
$2.1B
$1.4B
Q2 24
$1.1B
$-3.8B
Q1 24
$1.5B
$1.3B
Free Cash Flow
FG
FG
VRTX
VRTX
Q4 25
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$778.2M
Q4 24
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
Q1 24
$1.2B
FCF Margin
FG
FG
VRTX
VRTX
Q4 25
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
28.1%
Q4 24
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Q1 24
46.0%
Capex Intensity
FG
FG
VRTX
VRTX
Q4 25
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
1.5%
Q4 24
3.2%
Q3 24
2.4%
Q2 24
2.6%
Q1 24
2.5%
Cash Conversion
FG
FG
VRTX
VRTX
Q4 25
9.13×
0.42×
Q3 25
7.94×
1.15×
Q2 25
40.50×
1.04×
Q1 25
1.27×
Q4 24
4.04×
0.64×
Q3 24
1.31×
Q2 24
5.20×
Q1 24
13.34×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FG
FG

Segment breakdown not available.

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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