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Side-by-side financial comparison of FISERV INC (FISV) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

FISERV INC is the larger business by last-quarter revenue ($5.3B vs $3.2B, roughly 1.7× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 15.3%, a 22.0% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 0.6%). FISERV INC produced more free cash flow last quarter ($1.5B vs $348.6M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 4.0%).

Fiserv, Inc. is an American multinational financial technology company headquartered in Milwaukee, Wisconsin. The company processes debit and credit card transactions, loyalty programs, loans, electronic bill pay, wires and ACH transfers, check deposits, and ATM transactions on behalf of banking institutions. The company also produces debit and credit cards and point of sale terminals.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

FISV vs VRTX — Head-to-Head

Bigger by revenue
FISV
FISV
1.7× larger
FISV
$5.3B
$3.2B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+8.9% gap
VRTX
9.5%
0.6%
FISV
Higher net margin
VRTX
VRTX
22.0% more per $
VRTX
37.3%
15.3%
FISV
More free cash flow
FISV
FISV
$1.2B more FCF
FISV
$1.5B
$348.6M
VRTX
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
4.0%
FISV

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FISV
FISV
VRTX
VRTX
Revenue
$5.3B
$3.2B
Net Profit
$811.0M
$1.2B
Gross Margin
85.4%
Operating Margin
24.4%
37.8%
Net Margin
15.3%
37.3%
Revenue YoY
0.6%
9.5%
Net Profit YoY
-13.5%
30.5%
EPS (diluted)
$1.51
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FISV
FISV
VRTX
VRTX
Q4 25
$5.3B
$3.2B
Q3 25
$5.3B
$3.1B
Q2 25
$5.5B
$3.0B
Q1 25
$5.1B
$2.8B
Q4 24
$5.3B
$2.9B
Q3 24
$5.2B
$2.8B
Q2 24
$5.1B
$2.6B
Q1 24
$4.9B
$2.7B
Net Profit
FISV
FISV
VRTX
VRTX
Q4 25
$811.0M
$1.2B
Q3 25
$792.0M
$1.1B
Q2 25
$1.0B
$1.0B
Q1 25
$851.0M
$646.3M
Q4 24
$938.0M
$913.0M
Q3 24
$564.0M
$1.0B
Q2 24
$894.0M
$-3.6B
Q1 24
$735.0M
$1.1B
Gross Margin
FISV
FISV
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Q1 24
87.3%
Operating Margin
FISV
FISV
VRTX
VRTX
Q4 25
24.4%
37.8%
Q3 25
27.3%
38.6%
Q2 25
30.7%
38.8%
Q1 25
27.2%
22.7%
Q4 24
31.8%
35.2%
Q3 24
30.7%
40.3%
Q2 24
28.0%
-132.9%
Q1 24
24.2%
42.4%
Net Margin
FISV
FISV
VRTX
VRTX
Q4 25
15.3%
37.3%
Q3 25
15.0%
35.2%
Q2 25
18.6%
34.8%
Q1 25
16.6%
23.3%
Q4 24
17.9%
31.4%
Q3 24
10.8%
37.7%
Q2 24
17.5%
-135.8%
Q1 24
15.1%
40.9%
EPS (diluted)
FISV
FISV
VRTX
VRTX
Q4 25
$1.51
$4.64
Q3 25
$1.46
$4.20
Q2 25
$1.86
$3.99
Q1 25
$1.51
$2.49
Q4 24
$1.63
$3.62
Q3 24
$0.98
$4.01
Q2 24
$1.53
$-13.92
Q1 24
$1.24
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FISV
FISV
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$798.0M
$6.6B
Total DebtLower is stronger
$27.8B
Stockholders' EquityBook value
$25.8B
$18.7B
Total Assets
$80.1B
$25.6B
Debt / EquityLower = less leverage
1.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FISV
FISV
VRTX
VRTX
Q4 25
$798.0M
$6.6B
Q3 25
$1.1B
$6.3B
Q2 25
$999.0M
$6.4B
Q1 25
$1.2B
$6.2B
Q4 24
$1.2B
$6.1B
Q3 24
$1.2B
$6.5B
Q2 24
$1.2B
$5.8B
Q1 24
$1.2B
$10.2B
Total Debt
FISV
FISV
VRTX
VRTX
Q4 25
$27.8B
Q3 25
$28.9B
Q2 25
$28.1B
Q1 25
$27.0B
Q4 24
$23.7B
Q3 24
$24.1B
Q2 24
$24.4B
Q1 24
$23.8B
Stockholders' Equity
FISV
FISV
VRTX
VRTX
Q4 25
$25.8B
$18.7B
Q3 25
$25.1B
$17.3B
Q2 25
$25.2B
$17.2B
Q1 25
$25.9B
$16.5B
Q4 24
$27.1B
$16.4B
Q3 24
$27.8B
$15.6B
Q2 24
$28.2B
$14.8B
Q1 24
$28.8B
$18.5B
Total Assets
FISV
FISV
VRTX
VRTX
Q4 25
$80.1B
$25.6B
Q3 25
$79.4B
$24.9B
Q2 25
$81.5B
$24.0B
Q1 25
$80.4B
$22.9B
Q4 24
$77.2B
$22.5B
Q3 24
$79.8B
$22.2B
Q2 24
$93.4B
$20.1B
Q1 24
$92.7B
$23.9B
Debt / Equity
FISV
FISV
VRTX
VRTX
Q4 25
1.08×
Q3 25
1.15×
Q2 25
1.11×
Q1 25
1.04×
Q4 24
0.88×
Q3 24
0.87×
Q2 24
0.87×
Q1 24
0.82×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FISV
FISV
VRTX
VRTX
Operating Cash FlowLast quarter
$1.9B
$498.0M
Free Cash FlowOCF − Capex
$1.5B
$348.6M
FCF MarginFCF / Revenue
28.4%
10.9%
Capex IntensityCapex / Revenue
8.4%
4.7%
Cash ConversionOCF / Net Profit
2.40×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$4.3B
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FISV
FISV
VRTX
VRTX
Q4 25
$1.9B
$498.0M
Q3 25
$1.8B
$1.2B
Q2 25
$1.7B
$1.1B
Q1 25
$648.0M
$818.9M
Q4 24
$2.2B
$584.6M
Q3 24
$2.2B
$1.4B
Q2 24
$1.3B
$-3.8B
Q1 24
$831.0M
$1.3B
Free Cash Flow
FISV
FISV
VRTX
VRTX
Q4 25
$1.5B
$348.6M
Q3 25
$1.3B
$1.1B
Q2 25
$1.2B
$927.4M
Q1 25
$313.0M
$778.2M
Q4 24
$1.8B
$492.0M
Q3 24
$1.8B
$1.3B
Q2 24
$993.0M
$-3.8B
Q1 24
$411.0M
$1.2B
FCF Margin
FISV
FISV
VRTX
VRTX
Q4 25
28.4%
10.9%
Q3 25
24.7%
37.0%
Q2 25
21.5%
31.3%
Q1 25
6.1%
28.1%
Q4 24
34.7%
16.9%
Q3 24
35.2%
47.0%
Q2 24
19.4%
-144.5%
Q1 24
8.4%
46.0%
Capex Intensity
FISV
FISV
VRTX
VRTX
Q4 25
8.4%
4.7%
Q3 25
9.6%
3.3%
Q2 25
8.7%
4.9%
Q1 25
6.5%
1.5%
Q4 24
7.6%
3.2%
Q3 24
7.7%
2.4%
Q2 24
6.8%
2.6%
Q1 24
8.6%
2.5%
Cash Conversion
FISV
FISV
VRTX
VRTX
Q4 25
2.40×
0.42×
Q3 25
2.28×
1.15×
Q2 25
1.62×
1.04×
Q1 25
0.76×
1.27×
Q4 24
2.37×
0.64×
Q3 24
3.97×
1.31×
Q2 24
1.50×
Q1 24
1.13×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FISV
FISV

Small Business$1.7B32%
Products$1.0B19%
Digital Payments$960.0M18%
Issuing$792.0M15%
Enterprise$587.0M11%
Processing$265.0M5%
Affiliated Entity$18.0M0%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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