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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and NICOLET BANKSHARES INC (NIC). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $104.0M, roughly 1.8× NICOLET BANKSHARES INC). NICOLET BANKSHARES INC runs the higher net margin — 38.8% vs 0.9%, a 37.9% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 12.5%). NICOLET BANKSHARES INC produced more free cash flow last quarter ($149.4M vs $16.0M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs 12.5%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Nicolet Bankshares, Inc. is a U.S. regional bank holding company based in Green Bay, Wisconsin. They are the parent company of Nicolet National Bank, the second largest Wisconsin-based bank.
FOLD vs NIC — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $104.0M |
| Net Profit | $1.7M | $40.3M |
| Gross Margin | 85.7% | — |
| Operating Margin | 8.6% | 48.3% |
| Net Margin | 0.9% | 38.8% |
| Revenue YoY | 23.7% | 12.5% |
| Net Profit YoY | -88.5% | 16.9% |
| EPS (diluted) | $0.00 | $2.63 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $104.0M | ||
| Q3 25 | $169.1M | $102.9M | ||
| Q2 25 | $154.7M | $95.7M | ||
| Q1 25 | $125.2M | $89.4M | ||
| Q4 24 | $149.7M | $92.4M | ||
| Q3 24 | $141.5M | $90.7M | ||
| Q2 24 | $126.7M | $85.0M | ||
| Q1 24 | $110.4M | $82.2M |
| Q4 25 | $1.7M | $40.3M | ||
| Q3 25 | $17.3M | $41.7M | ||
| Q2 25 | $-24.4M | $36.0M | ||
| Q1 25 | $-21.7M | $32.6M | ||
| Q4 24 | $14.7M | $34.5M | ||
| Q3 24 | $-6.7M | $32.5M | ||
| Q2 24 | $-15.7M | $29.3M | ||
| Q1 24 | $-48.4M | $27.8M |
| Q4 25 | 85.7% | — | ||
| Q3 25 | 88.5% | — | ||
| Q2 25 | 90.2% | — | ||
| Q1 25 | 90.7% | — | ||
| Q4 24 | 90.1% | — | ||
| Q3 24 | 90.6% | — | ||
| Q2 24 | 91.1% | — | ||
| Q1 24 | 87.7% | — |
| Q4 25 | 8.6% | 48.3% | ||
| Q3 25 | 20.3% | 50.4% | ||
| Q2 25 | -6.1% | 46.8% | ||
| Q1 25 | -6.3% | 44.9% | ||
| Q4 24 | 10.7% | 46.8% | ||
| Q3 24 | 15.3% | 45.0% | ||
| Q2 24 | 11.8% | 43.3% | ||
| Q1 24 | -25.1% | 41.8% |
| Q4 25 | 0.9% | 38.8% | ||
| Q3 25 | 10.2% | 40.6% | ||
| Q2 25 | -15.8% | 37.6% | ||
| Q1 25 | -17.3% | 36.4% | ||
| Q4 24 | 9.8% | 37.3% | ||
| Q3 24 | -4.8% | 35.8% | ||
| Q2 24 | -12.4% | 34.5% | ||
| Q1 24 | -43.9% | 33.8% |
| Q4 25 | $0.00 | $2.63 | ||
| Q3 25 | $0.06 | $2.73 | ||
| Q2 25 | $-0.08 | $2.34 | ||
| Q1 25 | $-0.07 | $2.08 | ||
| Q4 24 | $0.05 | $2.21 | ||
| Q3 24 | $-0.02 | $2.10 | ||
| Q2 24 | $-0.05 | $1.92 | ||
| Q1 24 | $-0.16 | $1.82 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | — |
| Total DebtLower is stronger | $392.7M | $134.9M |
| Stockholders' EquityBook value | $274.2M | $1.3B |
| Total Assets | $949.9M | $9.2B |
| Debt / EquityLower = less leverage | 1.43× | 0.11× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | — | ||
| Q3 25 | $263.8M | — | ||
| Q2 25 | $231.0M | — | ||
| Q1 25 | $250.6M | — | ||
| Q4 24 | $249.9M | — | ||
| Q3 24 | $249.8M | — | ||
| Q2 24 | $260.1M | — | ||
| Q1 24 | $239.6M | — |
| Q4 25 | $392.7M | $134.9M | ||
| Q3 25 | $392.0M | $134.6M | ||
| Q2 25 | $391.3M | $134.3M | ||
| Q1 25 | $390.7M | $156.6M | ||
| Q4 24 | $390.1M | $161.4M | ||
| Q3 24 | $389.5M | $161.2M | ||
| Q2 24 | $388.9M | $162.4M | ||
| Q1 24 | $388.4M | $162.3M |
| Q4 25 | $274.2M | $1.3B | ||
| Q3 25 | $230.4M | $1.2B | ||
| Q2 25 | $204.3M | $1.2B | ||
| Q1 25 | $193.6M | $1.2B | ||
| Q4 24 | $194.0M | $1.2B | ||
| Q3 24 | $178.8M | $1.1B | ||
| Q2 24 | $132.5M | $1.1B | ||
| Q1 24 | $130.7M | $1.1B |
| Q4 25 | $949.9M | $9.2B | ||
| Q3 25 | $868.8M | $9.0B | ||
| Q2 25 | $815.3M | $8.9B | ||
| Q1 25 | $789.8M | $9.0B | ||
| Q4 24 | $785.0M | $8.8B | ||
| Q3 24 | $786.6M | $8.6B | ||
| Q2 24 | $749.5M | $8.6B | ||
| Q1 24 | $721.8M | $8.4B |
| Q4 25 | 1.43× | 0.11× | ||
| Q3 25 | 1.70× | 0.11× | ||
| Q2 25 | 1.92× | 0.11× | ||
| Q1 25 | 2.02× | 0.13× | ||
| Q4 24 | 2.01× | 0.14× | ||
| Q3 24 | 2.18× | 0.14× | ||
| Q2 24 | 2.93× | 0.15× | ||
| Q1 24 | 2.97× | 0.15× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $153.5M |
| Free Cash FlowOCF − Capex | $16.0M | $149.4M |
| FCF MarginFCF / Revenue | 8.6% | 143.7% |
| Capex IntensityCapex / Revenue | 0.2% | 3.9% |
| Cash ConversionOCF / Net Profit | 9.62× | 3.81× |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $275.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $153.5M | ||
| Q3 25 | $35.7M | $45.9M | ||
| Q2 25 | $-26.5M | $38.9M | ||
| Q1 25 | $7.8M | $41.8M | ||
| Q4 24 | $-3.9M | $133.7M | ||
| Q3 24 | $-23.0M | $39.6M | ||
| Q2 24 | $22.7M | $37.3M | ||
| Q1 24 | $-29.7M | $23.4M |
| Q4 25 | $16.0M | $149.4M | ||
| Q3 25 | $35.3M | $45.9M | ||
| Q2 25 | $-28.9M | $38.4M | ||
| Q1 25 | $7.5M | $41.3M | ||
| Q4 24 | $-4.2M | $116.8M | ||
| Q3 24 | $-23.3M | $34.7M | ||
| Q2 24 | $21.6M | $34.4M | ||
| Q1 24 | $-31.5M | $20.1M |
| Q4 25 | 8.6% | 143.7% | ||
| Q3 25 | 20.9% | 44.6% | ||
| Q2 25 | -18.7% | 40.1% | ||
| Q1 25 | 6.0% | 46.2% | ||
| Q4 24 | -2.8% | 126.4% | ||
| Q3 24 | -16.5% | 38.3% | ||
| Q2 24 | 17.0% | 40.5% | ||
| Q1 24 | -28.5% | 24.4% |
| Q4 25 | 0.2% | 3.9% | ||
| Q3 25 | 0.2% | 0.0% | ||
| Q2 25 | 1.6% | 0.6% | ||
| Q1 25 | 0.2% | 0.5% | ||
| Q4 24 | 0.2% | 18.3% | ||
| Q3 24 | 0.3% | 5.4% | ||
| Q2 24 | 0.9% | 3.5% | ||
| Q1 24 | 1.6% | 4.0% |
| Q4 25 | 9.62× | 3.81× | ||
| Q3 25 | 2.06× | 1.10× | ||
| Q2 25 | — | 1.08× | ||
| Q1 25 | — | 1.28× | ||
| Q4 24 | -0.27× | 3.88× | ||
| Q3 24 | — | 1.22× | ||
| Q2 24 | — | 1.28× | ||
| Q1 24 | — | 0.84× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
NIC
Segment breakdown not available.
