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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and Enpro Inc. (NPO). Click either name above to swap in a different company.
Enpro Inc. is the larger business by last-quarter revenue ($295.4M vs $185.2M, roughly 1.6× AMICUS THERAPEUTICS, INC.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -10.8%, a 11.7% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 14.3%). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs 7.1%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Enpro is a US-based industrial technology company that designs and manufactures products and materials for technology-intensive sectors. The company serves industries such as semiconductors, aerospace, power generation, heavy-duty trucking, agricultural machinery, chemical processing, pulp and paper, and life sciences from 61 primary manufacturing facilities located in 12 countries, worldwide. It is organized under three segments: Sealing Technologies, Advanced Surface Technologies, and Engin...
FOLD vs NPO — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $295.4M |
| Net Profit | $1.7M | $-32.0M |
| Gross Margin | 85.7% | 42.1% |
| Operating Margin | 8.6% | 11.2% |
| Net Margin | 0.9% | -10.8% |
| Revenue YoY | 23.7% | 14.3% |
| Net Profit YoY | -88.5% | -330.2% |
| EPS (diluted) | $0.00 | $-1.50 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $295.4M | ||
| Q3 25 | $169.1M | $286.6M | ||
| Q2 25 | $154.7M | $288.1M | ||
| Q1 25 | $125.2M | $273.2M | ||
| Q4 24 | $149.7M | $258.4M | ||
| Q3 24 | $141.5M | $260.9M | ||
| Q2 24 | $126.7M | $271.9M | ||
| Q1 24 | $110.4M | $257.5M |
| Q4 25 | $1.7M | $-32.0M | ||
| Q3 25 | $17.3M | $21.6M | ||
| Q2 25 | $-24.4M | $26.4M | ||
| Q1 25 | $-21.7M | $24.5M | ||
| Q4 24 | $14.7M | $13.9M | ||
| Q3 24 | $-6.7M | $19.8M | ||
| Q2 24 | $-15.7M | $26.7M | ||
| Q1 24 | $-48.4M | $12.5M |
| Q4 25 | 85.7% | 42.1% | ||
| Q3 25 | 88.5% | 41.9% | ||
| Q2 25 | 90.2% | 43.3% | ||
| Q1 25 | 90.7% | 43.3% | ||
| Q4 24 | 90.1% | 42.3% | ||
| Q3 24 | 90.6% | 42.3% | ||
| Q2 24 | 91.1% | 43.8% | ||
| Q1 24 | 87.7% | 41.2% |
| Q4 25 | 8.6% | 11.2% | ||
| Q3 25 | 20.3% | 14.3% | ||
| Q2 25 | -6.1% | 15.9% | ||
| Q1 25 | -6.3% | 15.3% | ||
| Q4 24 | 10.7% | 12.5% | ||
| Q3 24 | 15.3% | 13.1% | ||
| Q2 24 | 11.8% | 17.7% | ||
| Q1 24 | -25.1% | 10.9% |
| Q4 25 | 0.9% | -10.8% | ||
| Q3 25 | 10.2% | 7.5% | ||
| Q2 25 | -15.8% | 9.2% | ||
| Q1 25 | -17.3% | 9.0% | ||
| Q4 24 | 9.8% | 5.4% | ||
| Q3 24 | -4.8% | 7.6% | ||
| Q2 24 | -12.4% | 9.8% | ||
| Q1 24 | -43.9% | 4.9% |
| Q4 25 | $0.00 | $-1.50 | ||
| Q3 25 | $0.06 | $1.01 | ||
| Q2 25 | $-0.08 | $1.25 | ||
| Q1 25 | $-0.07 | $1.15 | ||
| Q4 24 | $0.05 | $0.65 | ||
| Q3 24 | $-0.02 | $0.94 | ||
| Q2 24 | $-0.05 | $1.27 | ||
| Q1 24 | $-0.16 | $0.59 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $114.7M |
| Total DebtLower is stronger | $392.7M | $655.3M |
| Stockholders' EquityBook value | $274.2M | $1.5B |
| Total Assets | $949.9M | $2.7B |
| Debt / EquityLower = less leverage | 1.43× | 0.42× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | $114.7M | ||
| Q3 25 | $263.8M | $132.9M | ||
| Q2 25 | $231.0M | $107.1M | ||
| Q1 25 | $250.6M | $240.3M | ||
| Q4 24 | $249.9M | $236.3M | ||
| Q3 24 | $249.8M | $206.9M | ||
| Q2 24 | $260.1M | $175.9M | ||
| Q1 24 | $239.6M | $163.9M |
| Q4 25 | $392.7M | $655.3M | ||
| Q3 25 | $392.0M | — | ||
| Q2 25 | $391.3M | — | ||
| Q1 25 | $390.7M | — | ||
| Q4 24 | $390.1M | $640.1M | ||
| Q3 24 | $389.5M | — | ||
| Q2 24 | $388.9M | — | ||
| Q1 24 | $388.4M | $644.9M |
| Q4 25 | $274.2M | $1.5B | ||
| Q3 25 | $230.4M | $1.5B | ||
| Q2 25 | $204.3M | $1.5B | ||
| Q1 25 | $193.6M | $1.5B | ||
| Q4 24 | $194.0M | $1.4B | ||
| Q3 24 | $178.8M | $1.5B | ||
| Q2 24 | $132.5M | $1.4B | ||
| Q1 24 | $130.7M | $1.4B |
| Q4 25 | $949.9M | $2.7B | ||
| Q3 25 | $868.8M | $2.4B | ||
| Q2 25 | $815.3M | $2.4B | ||
| Q1 25 | $789.8M | $2.5B | ||
| Q4 24 | $785.0M | $2.5B | ||
| Q3 24 | $786.6M | $2.5B | ||
| Q2 24 | $749.5M | $2.5B | ||
| Q1 24 | $721.8M | $2.5B |
| Q4 25 | 1.43× | 0.42× | ||
| Q3 25 | 1.70× | — | ||
| Q2 25 | 1.92× | — | ||
| Q1 25 | 2.02× | — | ||
| Q4 24 | 2.01× | 0.45× | ||
| Q3 24 | 2.18× | — | ||
| Q2 24 | 2.93× | — | ||
| Q1 24 | 2.97× | 0.46× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | — |
| Free Cash FlowOCF − Capex | $16.0M | — |
| FCF MarginFCF / Revenue | 8.6% | — |
| Capex IntensityCapex / Revenue | 0.2% | 4.1% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | — | ||
| Q3 25 | $35.7M | $65.3M | ||
| Q2 25 | $-26.5M | $52.2M | ||
| Q1 25 | $7.8M | $21.0M | ||
| Q4 24 | $-3.9M | $59.4M | ||
| Q3 24 | $-23.0M | $54.0M | ||
| Q2 24 | $22.7M | $43.2M | ||
| Q1 24 | $-29.7M | $6.3M |
| Q4 25 | $16.0M | — | ||
| Q3 25 | $35.3M | $53.4M | ||
| Q2 25 | $-28.9M | $42.3M | ||
| Q1 25 | $7.5M | $13.0M | ||
| Q4 24 | $-4.2M | $49.1M | ||
| Q3 24 | $-23.3M | $48.3M | ||
| Q2 24 | $21.6M | $38.3M | ||
| Q1 24 | $-31.5M | $-1.9M |
| Q4 25 | 8.6% | — | ||
| Q3 25 | 20.9% | 18.6% | ||
| Q2 25 | -18.7% | 14.7% | ||
| Q1 25 | 6.0% | 4.8% | ||
| Q4 24 | -2.8% | 19.0% | ||
| Q3 24 | -16.5% | 18.5% | ||
| Q2 24 | 17.0% | 14.1% | ||
| Q1 24 | -28.5% | -0.7% |
| Q4 25 | 0.2% | 4.1% | ||
| Q3 25 | 0.2% | 4.2% | ||
| Q2 25 | 1.6% | 3.4% | ||
| Q1 25 | 0.2% | 2.9% | ||
| Q4 24 | 0.2% | 4.0% | ||
| Q3 24 | 0.3% | 2.2% | ||
| Q2 24 | 0.9% | 1.8% | ||
| Q1 24 | 1.6% | 3.2% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | 3.02× | ||
| Q2 25 | — | 1.98× | ||
| Q1 25 | — | 0.86× | ||
| Q4 24 | -0.27× | 4.27× | ||
| Q3 24 | — | 2.73× | ||
| Q2 24 | — | 1.62× | ||
| Q1 24 | — | 0.50× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
NPO
| Sealing Technologies Segment | $187.0M | 63% |
| General Industrial | $71.3M | 24% |
| Power Generation | $19.9M | 7% |
| Oiland Gas Market | $15.0M | 5% |
| Semiconductors | $2.2M | 1% |
