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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and Perimeter Solutions, Inc. (PRM). Click either name above to swap in a different company.

AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $102.8M, roughly 1.8× Perimeter Solutions, Inc.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -136.5%, a 137.4% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 19.2%). AMICUS THERAPEUTICS, INC. produced more free cash flow last quarter ($16.0M vs $11.6M). Over the past eight quarters, Perimeter Solutions, Inc.'s revenue compounded faster (31.9% CAGR vs 29.5%).

Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.

Perimeter 81 is an Israeli cloud and network security company that develops secure remote networks, based on the zero trust architecture, for organizations. Its technology replaces legacy security appliances like VPNs and firewalls.

FOLD vs PRM — Head-to-Head

Bigger by revenue
FOLD
FOLD
1.8× larger
FOLD
$185.2M
$102.8M
PRM
Growing faster (revenue YoY)
FOLD
FOLD
+4.6% gap
FOLD
23.7%
19.2%
PRM
Higher net margin
FOLD
FOLD
137.4% more per $
FOLD
0.9%
-136.5%
PRM
More free cash flow
FOLD
FOLD
$4.3M more FCF
FOLD
$16.0M
$11.6M
PRM
Faster 2-yr revenue CAGR
PRM
PRM
Annualised
PRM
31.9%
29.5%
FOLD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FOLD
FOLD
PRM
PRM
Revenue
$185.2M
$102.8M
Net Profit
$1.7M
$-140.2M
Gross Margin
85.7%
45.2%
Operating Margin
8.6%
-160.7%
Net Margin
0.9%
-136.5%
Revenue YoY
23.7%
19.2%
Net Profit YoY
-88.5%
-197.3%
EPS (diluted)
$0.00
$-0.89

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FOLD
FOLD
PRM
PRM
Q4 25
$185.2M
$102.8M
Q3 25
$169.1M
$315.4M
Q2 25
$154.7M
$162.6M
Q1 25
$125.2M
$72.0M
Q4 24
$149.7M
$86.2M
Q3 24
$141.5M
$288.4M
Q2 24
$126.7M
$127.3M
Q1 24
$110.4M
$59.0M
Net Profit
FOLD
FOLD
PRM
PRM
Q4 25
$1.7M
$-140.2M
Q3 25
$17.3M
$-90.7M
Q2 25
$-24.4M
$-32.2M
Q1 25
$-21.7M
$56.7M
Q4 24
$14.7M
$144.2M
Q3 24
$-6.7M
$-89.2M
Q2 24
$-15.7M
$21.6M
Q1 24
$-48.4M
$-82.6M
Gross Margin
FOLD
FOLD
PRM
PRM
Q4 25
85.7%
45.2%
Q3 25
88.5%
63.1%
Q2 25
90.2%
62.4%
Q1 25
90.7%
39.1%
Q4 24
90.1%
48.6%
Q3 24
90.6%
62.8%
Q2 24
91.1%
57.6%
Q1 24
87.7%
35.1%
Operating Margin
FOLD
FOLD
PRM
PRM
Q4 25
8.6%
-160.7%
Q3 25
20.3%
-27.7%
Q2 25
-6.1%
-16.1%
Q1 25
-6.3%
Q4 24
10.7%
71.1%
Q3 24
15.3%
-12.2%
Q2 24
11.8%
35.4%
Q1 24
-25.1%
-126.8%
Net Margin
FOLD
FOLD
PRM
PRM
Q4 25
0.9%
-136.5%
Q3 25
10.2%
-28.7%
Q2 25
-15.8%
-19.8%
Q1 25
-17.3%
78.7%
Q4 24
9.8%
167.2%
Q3 24
-4.8%
-30.9%
Q2 24
-12.4%
17.0%
Q1 24
-43.9%
-139.8%
EPS (diluted)
FOLD
FOLD
PRM
PRM
Q4 25
$0.00
$-0.89
Q3 25
$0.06
$-0.62
Q2 25
$-0.08
$-0.22
Q1 25
$-0.07
$0.36
Q4 24
$0.05
$1.00
Q3 24
$-0.02
$-0.61
Q2 24
$-0.05
$0.14
Q1 24
$-0.16
$-0.57

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FOLD
FOLD
PRM
PRM
Cash + ST InvestmentsLiquidity on hand
$293.5M
$325.9M
Total DebtLower is stronger
$392.7M
$669.1M
Stockholders' EquityBook value
$274.2M
$1.1B
Total Assets
$949.9M
$2.7B
Debt / EquityLower = less leverage
1.43×
0.59×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FOLD
FOLD
PRM
PRM
Q4 25
$293.5M
$325.9M
Q3 25
$263.8M
$340.6M
Q2 25
$231.0M
$140.7M
Q1 25
$250.6M
$200.1M
Q4 24
$249.9M
$198.5M
Q3 24
$249.8M
$223.1M
Q2 24
$260.1M
$43.2M
Q1 24
$239.6M
$38.7M
Total Debt
FOLD
FOLD
PRM
PRM
Q4 25
$392.7M
$669.1M
Q3 25
$392.0M
$668.8M
Q2 25
$391.3M
$668.4M
Q1 25
$390.7M
$668.1M
Q4 24
$390.1M
$667.8M
Q3 24
$389.5M
$667.4M
Q2 24
$388.9M
$667.1M
Q1 24
$388.4M
$666.8M
Stockholders' Equity
FOLD
FOLD
PRM
PRM
Q4 25
$274.2M
$1.1B
Q3 25
$230.4M
$1.1B
Q2 25
$204.3M
$1.2B
Q1 25
$193.6M
$1.2B
Q4 24
$194.0M
$1.2B
Q3 24
$178.8M
$1.0B
Q2 24
$132.5M
$1.1B
Q1 24
$130.7M
$1.1B
Total Assets
FOLD
FOLD
PRM
PRM
Q4 25
$949.9M
$2.7B
Q3 25
$868.8M
$2.6B
Q2 25
$815.3M
$2.5B
Q1 25
$789.8M
$2.4B
Q4 24
$785.0M
$2.4B
Q3 24
$786.6M
$2.5B
Q2 24
$749.5M
$2.3B
Q1 24
$721.8M
$2.3B
Debt / Equity
FOLD
FOLD
PRM
PRM
Q4 25
1.43×
0.59×
Q3 25
1.70×
0.60×
Q2 25
1.92×
0.57×
Q1 25
2.02×
0.55×
Q4 24
2.01×
0.58×
Q3 24
2.18×
0.67×
Q2 24
2.93×
0.62×
Q1 24
2.97×
0.63×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FOLD
FOLD
PRM
PRM
Operating Cash FlowLast quarter
$16.3M
$18.6M
Free Cash FlowOCF − Capex
$16.0M
$11.6M
FCF MarginFCF / Revenue
8.6%
11.3%
Capex IntensityCapex / Revenue
0.2%
6.8%
Cash ConversionOCF / Net Profit
9.62×
TTM Free Cash FlowTrailing 4 quarters
$29.8M
$208.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FOLD
FOLD
PRM
PRM
Q4 25
$16.3M
$18.6M
Q3 25
$35.7M
$198.7M
Q2 25
$-26.5M
$-2.9M
Q1 25
$7.8M
$23.7M
Q4 24
$-3.9M
$-6.0M
Q3 24
$-23.0M
$183.0M
Q2 24
$22.7M
$8.6M
Q1 24
$-29.7M
$2.8M
Free Cash Flow
FOLD
FOLD
PRM
PRM
Q4 25
$16.0M
$11.6M
Q3 25
$35.3M
$193.6M
Q2 25
$-28.9M
$-15.6M
Q1 25
$7.5M
$18.9M
Q4 24
$-4.2M
$-12.4M
Q3 24
$-23.3M
$179.1M
Q2 24
$21.6M
$5.0M
Q1 24
$-31.5M
$1.2M
FCF Margin
FOLD
FOLD
PRM
PRM
Q4 25
8.6%
11.3%
Q3 25
20.9%
61.4%
Q2 25
-18.7%
-9.6%
Q1 25
6.0%
26.3%
Q4 24
-2.8%
-14.4%
Q3 24
-16.5%
62.1%
Q2 24
17.0%
3.9%
Q1 24
-28.5%
2.1%
Capex Intensity
FOLD
FOLD
PRM
PRM
Q4 25
0.2%
6.8%
Q3 25
0.2%
1.6%
Q2 25
1.6%
7.8%
Q1 25
0.2%
6.7%
Q4 24
0.2%
7.5%
Q3 24
0.3%
1.3%
Q2 24
0.9%
2.9%
Q1 24
1.6%
2.6%
Cash Conversion
FOLD
FOLD
PRM
PRM
Q4 25
9.62×
Q3 25
2.06×
Q2 25
Q1 25
0.42×
Q4 24
-0.27×
-0.04×
Q3 24
Q2 24
0.40×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FOLD
FOLD

Other$105.8M57%
Galafold$64.8M35%
Pombiliti Opfolda$14.6M8%

PRM
PRM

Products$87.7M85%
Service And Other$14.8M14%

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