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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and Riot Platforms, Inc. (RIOT). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $152.8M, roughly 1.2× Riot Platforms, Inc.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -452.0%, a 452.9% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 7.2%). AMICUS THERAPEUTICS, INC. produced more free cash flow last quarter ($16.0M vs $-774.3M). Over the past eight quarters, Riot Platforms, Inc.'s revenue compounded faster (38.8% CAGR vs 29.5%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Riot Platforms, Inc. is a leading U.S.-based enterprise focused on Bitcoin mining, operating multiple large-scale, energy-efficient data centers across North America. It also invests in blockchain infrastructure development and holds Bitcoin as a core long-term reserve asset, centering its business strategy around the digital asset ecosystem.
FOLD vs RIOT — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $152.8M |
| Net Profit | $1.7M | $-690.7M |
| Gross Margin | 85.7% | — |
| Operating Margin | 8.6% | -447.9% |
| Net Margin | 0.9% | -452.0% |
| Revenue YoY | 23.7% | 7.2% |
| Net Profit YoY | -88.5% | -606.3% |
| EPS (diluted) | $0.00 | $-1.89 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $152.8M | ||
| Q3 25 | $169.1M | $180.2M | ||
| Q2 25 | $154.7M | $153.0M | ||
| Q1 25 | $125.2M | $161.4M | ||
| Q4 24 | $149.7M | $142.6M | ||
| Q3 24 | $141.5M | $84.8M | ||
| Q2 24 | $126.7M | $70.0M | ||
| Q1 24 | $110.4M | $79.3M |
| Q4 25 | $1.7M | $-690.7M | ||
| Q3 25 | $17.3M | $104.5M | ||
| Q2 25 | $-24.4M | $219.5M | ||
| Q1 25 | $-21.7M | $-296.4M | ||
| Q4 24 | $14.7M | $136.4M | ||
| Q3 24 | $-6.7M | $-154.4M | ||
| Q2 24 | $-15.7M | $-84.4M | ||
| Q1 24 | $-48.4M | $211.8M |
| Q4 25 | 85.7% | — | ||
| Q3 25 | 88.5% | — | ||
| Q2 25 | 90.2% | — | ||
| Q1 25 | 90.7% | — | ||
| Q4 24 | 90.1% | — | ||
| Q3 24 | 90.6% | — | ||
| Q2 24 | 91.1% | — | ||
| Q1 24 | 87.7% | — |
| Q4 25 | 8.6% | -447.9% | ||
| Q3 25 | 20.3% | 44.4% | ||
| Q2 25 | -6.1% | — | ||
| Q1 25 | -6.3% | -144.9% | ||
| Q4 24 | 10.7% | — | ||
| Q3 24 | 15.3% | -143.3% | ||
| Q2 24 | 11.8% | -167.2% | ||
| Q1 24 | -25.1% | — |
| Q4 25 | 0.9% | -452.0% | ||
| Q3 25 | 10.2% | 58.0% | ||
| Q2 25 | -15.8% | 143.4% | ||
| Q1 25 | -17.3% | -183.6% | ||
| Q4 24 | 9.8% | 95.7% | ||
| Q3 24 | -4.8% | -182.1% | ||
| Q2 24 | -12.4% | -120.6% | ||
| Q1 24 | -43.9% | 267.1% |
| Q4 25 | $0.00 | $-1.89 | ||
| Q3 25 | $0.06 | $0.26 | ||
| Q2 25 | $-0.08 | $0.58 | ||
| Q1 25 | $-0.07 | $-0.90 | ||
| Q4 24 | $0.05 | $0.39 | ||
| Q3 24 | $-0.02 | $-0.54 | ||
| Q2 24 | $-0.05 | $-0.32 | ||
| Q1 24 | $-0.16 | $0.51 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $233.5M |
| Total DebtLower is stronger | $392.7M | $840.8M |
| Stockholders' EquityBook value | $274.2M | $2.9B |
| Total Assets | $949.9M | $3.9B |
| Debt / EquityLower = less leverage | 1.43× | 0.29× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | $233.5M | ||
| Q3 25 | $263.8M | $330.7M | ||
| Q2 25 | $231.0M | $255.4M | ||
| Q1 25 | $250.6M | $163.7M | ||
| Q4 24 | $249.9M | $277.9M | ||
| Q3 24 | $249.8M | $355.7M | ||
| Q2 24 | $260.1M | $481.2M | ||
| Q1 24 | $239.6M | $688.5M |
| Q4 25 | $392.7M | $840.8M | ||
| Q3 25 | $392.0M | $5.3M | ||
| Q2 25 | $391.3M | $5.3M | ||
| Q1 25 | $390.7M | $5.3M | ||
| Q4 24 | $390.1M | $584.6M | ||
| Q3 24 | $389.5M | $5.7M | ||
| Q2 24 | $388.9M | — | ||
| Q1 24 | $388.4M | — |
| Q4 25 | $274.2M | $2.9B | ||
| Q3 25 | $230.4M | $3.5B | ||
| Q2 25 | $204.3M | $3.3B | ||
| Q1 25 | $193.6M | $2.9B | ||
| Q4 24 | $194.0M | $3.1B | ||
| Q3 24 | $178.8M | $2.7B | ||
| Q2 24 | $132.5M | $2.6B | ||
| Q1 24 | $130.7M | $2.5B |
| Q4 25 | $949.9M | $3.9B | ||
| Q3 25 | $868.8M | $4.5B | ||
| Q2 25 | $815.3M | $4.3B | ||
| Q1 25 | $789.8M | $3.7B | ||
| Q4 24 | $785.0M | $3.9B | ||
| Q3 24 | $786.6M | $2.9B | ||
| Q2 24 | $749.5M | $2.7B | ||
| Q1 24 | $721.8M | $2.6B |
| Q4 25 | 1.43× | 0.29× | ||
| Q3 25 | 1.70× | 0.00× | ||
| Q2 25 | 1.92× | 0.00× | ||
| Q1 25 | 2.02× | 0.00× | ||
| Q4 24 | 2.01× | 0.19× | ||
| Q3 24 | 2.18× | 0.00× | ||
| Q2 24 | 2.93× | — | ||
| Q1 24 | 2.97× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $-572.9M |
| Free Cash FlowOCF − Capex | $16.0M | $-774.3M |
| FCF MarginFCF / Revenue | 8.6% | -506.6% |
| Capex IntensityCapex / Revenue | 0.2% | 131.8% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $-1.4B |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $-572.9M | ||
| Q3 25 | $35.7M | $-114.0M | ||
| Q2 25 | $-26.5M | $-231.3M | ||
| Q1 25 | $7.8M | $-122.1M | ||
| Q4 24 | $-3.9M | $-255.1M | ||
| Q3 24 | $-23.0M | $-56.3M | ||
| Q2 24 | $22.7M | $-42.5M | ||
| Q1 24 | $-29.7M | $-57.9M |
| Q4 25 | $16.0M | $-774.3M | ||
| Q3 25 | $35.3M | $-139.7M | ||
| Q2 25 | $-28.9M | $-291.7M | ||
| Q1 25 | $7.5M | $-154.9M | ||
| Q4 24 | $-4.2M | $-495.4M | ||
| Q3 24 | $-23.3M | $-127.6M | ||
| Q2 24 | $21.6M | $-96.1M | ||
| Q1 24 | $-31.5M | $-115.2M |
| Q4 25 | 8.6% | -506.6% | ||
| Q3 25 | 20.9% | -77.5% | ||
| Q2 25 | -18.7% | -190.7% | ||
| Q1 25 | 6.0% | -96.0% | ||
| Q4 24 | -2.8% | -347.5% | ||
| Q3 24 | -16.5% | -150.5% | ||
| Q2 24 | 17.0% | -137.2% | ||
| Q1 24 | -28.5% | -145.2% |
| Q4 25 | 0.2% | 131.8% | ||
| Q3 25 | 0.2% | 14.3% | ||
| Q2 25 | 1.6% | 39.5% | ||
| Q1 25 | 0.2% | 20.4% | ||
| Q4 24 | 0.2% | 168.6% | ||
| Q3 24 | 0.3% | 84.1% | ||
| Q2 24 | 0.9% | 76.5% | ||
| Q1 24 | 1.6% | 72.3% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | -1.09× | ||
| Q2 25 | — | -1.05× | ||
| Q1 25 | — | — | ||
| Q4 24 | -0.27× | -1.87× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | -0.27× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
RIOT
| Bitcoin Mining Segment | $131.7M | 86% |
| Engineering Segment | $21.1M | 14% |
