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Side-by-side financial comparison of JFrog Ltd (FROG) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $145.3M, roughly 1.0× JFrog Ltd). JFrog Ltd runs the higher net margin — -10.5% vs -21.1%, a 10.6% gap on every dollar of revenue. On growth, JFrog Ltd posted the faster year-over-year revenue change (25.2% vs -19.2%). JFrog Ltd produced more free cash flow last quarter ($49.9M vs $-28.6M). Over the past eight quarters, JFrog Ltd's revenue compounded faster (20.4% CAGR vs -7.5%).

JFrog Ltd is a global DevOps technology provider that delivers end-to-end software release, artifact management, and security solutions. It serves clients across tech, finance, retail, and manufacturing sectors, helping teams streamline development and delivery workflows for cloud, on-premises, and hybrid infrastructure.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

FROG vs OPK — Head-to-Head

Bigger by revenue
OPK
OPK
1.0× larger
OPK
$148.5M
$145.3M
FROG
Growing faster (revenue YoY)
FROG
FROG
+44.3% gap
FROG
25.2%
-19.2%
OPK
Higher net margin
FROG
FROG
10.6% more per $
FROG
-10.5%
-21.1%
OPK
More free cash flow
FROG
FROG
$78.4M more FCF
FROG
$49.9M
$-28.6M
OPK
Faster 2-yr revenue CAGR
FROG
FROG
Annualised
FROG
20.4%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FROG
FROG
OPK
OPK
Revenue
$145.3M
$148.5M
Net Profit
$-15.2M
$-31.3M
Gross Margin
77.9%
43.1%
Operating Margin
-14.7%
-25.8%
Net Margin
-10.5%
-21.1%
Revenue YoY
25.2%
-19.2%
Net Profit YoY
34.4%
-322.8%
EPS (diluted)
$-0.13
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FROG
FROG
OPK
OPK
Q4 25
$145.3M
$148.5M
Q3 25
$136.9M
$151.7M
Q2 25
$127.2M
$156.8M
Q1 25
$122.4M
$150.0M
Q4 24
$116.1M
$183.6M
Q3 24
$109.1M
$173.6M
Q2 24
$103.0M
$182.2M
Q1 24
$100.3M
$173.7M
Net Profit
FROG
FROG
OPK
OPK
Q4 25
$-15.2M
$-31.3M
Q3 25
$-16.4M
$21.6M
Q2 25
$-21.7M
$-148.4M
Q1 25
$-18.5M
$-67.6M
Q4 24
$-23.2M
$14.0M
Q3 24
$-22.9M
$24.9M
Q2 24
$-14.3M
$-10.3M
Q1 24
$-8.8M
$-81.8M
Gross Margin
FROG
FROG
OPK
OPK
Q4 25
77.9%
43.1%
Q3 25
77.4%
32.9%
Q2 25
76.3%
31.5%
Q1 25
75.3%
28.4%
Q4 24
75.4%
46.1%
Q3 24
75.0%
23.1%
Q2 24
78.8%
28.4%
Q1 24
79.5%
24.2%
Operating Margin
FROG
FROG
OPK
OPK
Q4 25
-14.7%
-25.8%
Q3 25
-15.8%
31.7%
Q2 25
-20.4%
-38.3%
Q1 25
-18.8%
-44.8%
Q4 24
-21.9%
-18.0%
Q3 24
-27.4%
8.2%
Q2 24
-18.6%
-33.9%
Q1 24
-16.6%
-41.2%
Net Margin
FROG
FROG
OPK
OPK
Q4 25
-10.5%
-21.1%
Q3 25
-12.0%
14.3%
Q2 25
-17.0%
-94.7%
Q1 25
-15.1%
-45.1%
Q4 24
-20.0%
7.6%
Q3 24
-21.0%
14.3%
Q2 24
-13.9%
-5.7%
Q1 24
-8.8%
-47.1%
EPS (diluted)
FROG
FROG
OPK
OPK
Q4 25
$-0.13
$-0.04
Q3 25
$-0.14
$0.03
Q2 25
$-0.19
$-0.19
Q1 25
$-0.16
$-0.10
Q4 24
$-0.21
$0.02
Q3 24
$-0.21
$0.03
Q2 24
$-0.13
$-0.01
Q1 24
$-0.08
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FROG
FROG
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$704.4M
$364.4M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$887.4M
$1.3B
Total Assets
$1.3B
$1.9B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FROG
FROG
OPK
OPK
Q4 25
$704.4M
$364.4M
Q3 25
$651.1M
$412.0M
Q2 25
$611.7M
$267.3M
Q1 25
$563.5M
$428.8M
Q4 24
$522.0M
$426.6M
Q3 24
$467.8M
$400.1M
Q2 24
$591.3M
$40.6M
Q1 24
$579.6M
$75.6M
Total Debt
FROG
FROG
OPK
OPK
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
FROG
FROG
OPK
OPK
Q4 25
$887.4M
$1.3B
Q3 25
$859.4M
$1.3B
Q2 25
$826.5M
$1.3B
Q1 25
$800.0M
$1.3B
Q4 24
$773.5M
$1.4B
Q3 24
$756.2M
$1.4B
Q2 24
$721.4M
$1.4B
Q1 24
$707.8M
$1.3B
Total Assets
FROG
FROG
OPK
OPK
Q4 25
$1.3B
$1.9B
Q3 25
$1.3B
$2.0B
Q2 25
$1.2B
$2.0B
Q1 25
$1.2B
$2.1B
Q4 24
$1.1B
$2.2B
Q3 24
$1.1B
$2.3B
Q2 24
$1.0B
$2.0B
Q1 24
$997.1M
$2.0B
Debt / Equity
FROG
FROG
OPK
OPK
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FROG
FROG
OPK
OPK
Operating Cash FlowLast quarter
$50.7M
$-25.9M
Free Cash FlowOCF − Capex
$49.9M
$-28.6M
FCF MarginFCF / Revenue
34.3%
-19.3%
Capex IntensityCapex / Revenue
0.6%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$142.3M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FROG
FROG
OPK
OPK
Q4 25
$50.7M
$-25.9M
Q3 25
$30.2M
$-34.6M
Q2 25
$36.1M
$-83.4M
Q1 25
$28.8M
$-34.6M
Q4 24
$49.1M
$-44.4M
Q3 24
$27.6M
$-77.1M
Q2 24
$16.7M
$-26.4M
Q1 24
$17.5M
$-35.6M
Free Cash Flow
FROG
FROG
OPK
OPK
Q4 25
$49.9M
$-28.6M
Q3 25
$28.8M
$-37.8M
Q2 25
$35.5M
$-86.7M
Q1 25
$28.1M
$-37.7M
Q4 24
$48.5M
$-49.8M
Q3 24
$26.7M
$-85.0M
Q2 24
$16.0M
$-33.7M
Q1 24
$16.6M
$-40.0M
FCF Margin
FROG
FROG
OPK
OPK
Q4 25
34.3%
-19.3%
Q3 25
21.0%
-24.9%
Q2 25
27.9%
-55.3%
Q1 25
23.0%
-25.2%
Q4 24
41.8%
-27.1%
Q3 24
24.5%
-49.0%
Q2 24
15.5%
-18.5%
Q1 24
16.6%
-23.0%
Capex Intensity
FROG
FROG
OPK
OPK
Q4 25
0.6%
1.8%
Q3 25
1.0%
2.1%
Q2 25
0.5%
2.1%
Q1 25
0.5%
2.1%
Q4 24
0.5%
2.9%
Q3 24
0.9%
4.6%
Q2 24
0.7%
4.0%
Q1 24
0.8%
2.6%
Cash Conversion
FROG
FROG
OPK
OPK
Q4 25
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FROG
FROG

Segment breakdown not available.

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

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