vs

Side-by-side financial comparison of Fastly, Inc. (FSLY) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

Fastly, Inc. is the larger business by last-quarter revenue ($172.6M vs $148.5M, roughly 1.2× OPKO HEALTH, INC.). Fastly, Inc. runs the higher net margin — -9.0% vs -21.1%, a 12.1% gap on every dollar of revenue. On growth, Fastly, Inc. posted the faster year-over-year revenue change (22.8% vs -19.2%). Fastly, Inc. produced more free cash flow last quarter ($12.2M vs $-28.6M). Over the past eight quarters, Fastly, Inc.'s revenue compounded faster (13.7% CAGR vs -7.5%).

Fastly, Inc. is an American company based in San Francisco, which describes itself as a cloud computing company. Fastly provides content delivery network services, image optimization, and load balancing services. Fastly's cloud security services include denial-of-service attack protection, bot mitigation, and a web application firewall.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

FSLY vs OPK — Head-to-Head

Bigger by revenue
FSLY
FSLY
1.2× larger
FSLY
$172.6M
$148.5M
OPK
Growing faster (revenue YoY)
FSLY
FSLY
+41.9% gap
FSLY
22.8%
-19.2%
OPK
Higher net margin
FSLY
FSLY
12.1% more per $
FSLY
-9.0%
-21.1%
OPK
More free cash flow
FSLY
FSLY
$40.8M more FCF
FSLY
$12.2M
$-28.6M
OPK
Faster 2-yr revenue CAGR
FSLY
FSLY
Annualised
FSLY
13.7%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FSLY
FSLY
OPK
OPK
Revenue
$172.6M
$148.5M
Net Profit
$-15.5M
$-31.3M
Gross Margin
61.4%
43.1%
Operating Margin
-8.7%
-25.8%
Net Margin
-9.0%
-21.1%
Revenue YoY
22.8%
-19.2%
Net Profit YoY
52.9%
-322.8%
EPS (diluted)
$-0.10
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FSLY
FSLY
OPK
OPK
Q4 25
$172.6M
$148.5M
Q3 25
$158.2M
$151.7M
Q2 25
$148.7M
$156.8M
Q1 25
$144.5M
$150.0M
Q4 24
$140.6M
$183.6M
Q3 24
$137.2M
$173.6M
Q2 24
$132.4M
$182.2M
Q1 24
$133.5M
$173.7M
Net Profit
FSLY
FSLY
OPK
OPK
Q4 25
$-15.5M
$-31.3M
Q3 25
$-29.5M
$21.6M
Q2 25
$-37.5M
$-148.4M
Q1 25
$-39.1M
$-67.6M
Q4 24
$-32.9M
$14.0M
Q3 24
$-38.0M
$24.9M
Q2 24
$-43.7M
$-10.3M
Q1 24
$-43.4M
$-81.8M
Gross Margin
FSLY
FSLY
OPK
OPK
Q4 25
61.4%
43.1%
Q3 25
58.4%
32.9%
Q2 25
54.5%
31.5%
Q1 25
53.2%
28.4%
Q4 24
53.4%
46.1%
Q3 24
54.5%
23.1%
Q2 24
55.1%
28.4%
Q1 24
54.8%
24.2%
Operating Margin
FSLY
FSLY
OPK
OPK
Q4 25
-8.7%
-25.8%
Q3 25
-18.2%
31.7%
Q2 25
-24.8%
-38.3%
Q1 25
-26.4%
-44.8%
Q4 24
-24.4%
-18.0%
Q3 24
-29.6%
8.2%
Q2 24
-35.3%
-33.9%
Q1 24
-34.6%
-41.2%
Net Margin
FSLY
FSLY
OPK
OPK
Q4 25
-9.0%
-21.1%
Q3 25
-18.6%
14.3%
Q2 25
-25.2%
-94.7%
Q1 25
-27.1%
-45.1%
Q4 24
-23.4%
7.6%
Q3 24
-27.7%
14.3%
Q2 24
-33.0%
-5.7%
Q1 24
-32.5%
-47.1%
EPS (diluted)
FSLY
FSLY
OPK
OPK
Q4 25
$-0.10
$-0.04
Q3 25
$-0.20
$0.03
Q2 25
$-0.26
$-0.19
Q1 25
$-0.27
$-0.10
Q4 24
$-0.23
$0.02
Q3 24
$-0.27
$0.03
Q2 24
$-0.32
$-0.01
Q1 24
$-0.32
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FSLY
FSLY
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$361.8M
$364.4M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$929.6M
$1.3B
Total Assets
$1.5B
$1.9B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FSLY
FSLY
OPK
OPK
Q4 25
$361.8M
$364.4M
Q3 25
$342.9M
$412.0M
Q2 25
$321.2M
$267.3M
Q1 25
$307.3M
$428.8M
Q4 24
$295.9M
$426.6M
Q3 24
$308.2M
$400.1M
Q2 24
$311.8M
$40.6M
Q1 24
$329.5M
$75.6M
Total Debt
FSLY
FSLY
OPK
OPK
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
FSLY
FSLY
OPK
OPK
Q4 25
$929.6M
$1.3B
Q3 25
$937.0M
$1.3B
Q2 25
$942.6M
$1.3B
Q1 25
$957.0M
$1.3B
Q4 24
$965.3M
$1.4B
Q3 24
$969.5M
$1.4B
Q2 24
$981.2M
$1.4B
Q1 24
$991.8M
$1.3B
Total Assets
FSLY
FSLY
OPK
OPK
Q4 25
$1.5B
$1.9B
Q3 25
$1.5B
$2.0B
Q2 25
$1.5B
$2.0B
Q1 25
$1.4B
$2.1B
Q4 24
$1.5B
$2.2B
Q3 24
$1.5B
$2.3B
Q2 24
$1.5B
$2.0B
Q1 24
$1.5B
$2.0B
Debt / Equity
FSLY
FSLY
OPK
OPK
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FSLY
FSLY
OPK
OPK
Operating Cash FlowLast quarter
$22.4M
$-25.9M
Free Cash FlowOCF − Capex
$12.2M
$-28.6M
FCF MarginFCF / Revenue
7.1%
-19.3%
Capex IntensityCapex / Revenue
5.9%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$65.8M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FSLY
FSLY
OPK
OPK
Q4 25
$22.4M
$-25.9M
Q3 25
$28.9M
$-34.6M
Q2 25
$25.8M
$-83.4M
Q1 25
$17.3M
$-34.6M
Q4 24
$5.2M
$-44.4M
Q3 24
$5.0M
$-77.1M
Q2 24
$-4.9M
$-26.4M
Q1 24
$11.1M
$-35.6M
Free Cash Flow
FSLY
FSLY
OPK
OPK
Q4 25
$12.2M
$-28.6M
Q3 25
$22.9M
$-37.8M
Q2 25
$15.9M
$-86.7M
Q1 25
$14.7M
$-37.7M
Q4 24
$251.0K
$-49.8M
Q3 24
$3.0M
$-85.0M
Q2 24
$-6.7M
$-33.7M
Q1 24
$9.5M
$-40.0M
FCF Margin
FSLY
FSLY
OPK
OPK
Q4 25
7.1%
-19.3%
Q3 25
14.5%
-24.9%
Q2 25
10.7%
-55.3%
Q1 25
10.2%
-25.2%
Q4 24
0.2%
-27.1%
Q3 24
2.2%
-49.0%
Q2 24
-5.1%
-18.5%
Q1 24
7.1%
-23.0%
Capex Intensity
FSLY
FSLY
OPK
OPK
Q4 25
5.9%
1.8%
Q3 25
3.8%
2.1%
Q2 25
6.6%
2.1%
Q1 25
1.8%
2.1%
Q4 24
3.5%
2.9%
Q3 24
1.5%
4.6%
Q2 24
1.3%
4.0%
Q1 24
1.2%
2.6%
Cash Conversion
FSLY
FSLY
OPK
OPK
Q4 25
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FSLY
FSLY

Network Services$130.8M76%
Security$35.4M21%
Other$6.4M4%

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

Related Comparisons