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Side-by-side financial comparison of Fastly, Inc. (FSLY) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

Fastly, Inc. is the larger business by last-quarter revenue ($173.0M vs $103.7M, roughly 1.7× Twist Bioscience Corp). Fastly, Inc. runs the higher net margin — -11.9% vs -29.4%, a 17.6% gap on every dollar of revenue. On growth, Fastly, Inc. posted the faster year-over-year revenue change (19.8% vs 16.9%). Fastly, Inc. produced more free cash flow last quarter ($4.1M vs $-34.8M).

Fastly, Inc. is an American company based in San Francisco, which describes itself as a cloud computing company. Fastly provides content delivery network services, image optimization, and load balancing services. Fastly's cloud security services include denial-of-service attack protection, bot mitigation, and a web application firewall.

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

FSLY vs TWST — Head-to-Head

Bigger by revenue
FSLY
FSLY
1.7× larger
FSLY
$173.0M
$103.7M
TWST
Growing faster (revenue YoY)
FSLY
FSLY
+2.9% gap
FSLY
19.8%
16.9%
TWST
Higher net margin
FSLY
FSLY
17.6% more per $
FSLY
-11.9%
-29.4%
TWST
More free cash flow
FSLY
FSLY
$38.9M more FCF
FSLY
$4.1M
$-34.8M
TWST

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
FSLY
FSLY
TWST
TWST
Revenue
$173.0M
$103.7M
Net Profit
$-20.5M
$-30.5M
Gross Margin
62.5%
52.0%
Operating Margin
23.7%
-31.7%
Net Margin
-11.9%
-29.4%
Revenue YoY
19.8%
16.9%
Net Profit YoY
47.6%
3.4%
EPS (diluted)
$-0.13
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FSLY
FSLY
TWST
TWST
Q1 26
$173.0M
Q4 25
$172.6M
$103.7M
Q3 25
$158.2M
Q2 25
$148.7M
Q1 25
$144.5M
Q4 24
$140.6M
Q3 24
$137.2M
Q2 24
$132.4M
Net Profit
FSLY
FSLY
TWST
TWST
Q1 26
$-20.5M
Q4 25
$-15.5M
$-30.5M
Q3 25
$-29.5M
Q2 25
$-37.5M
Q1 25
$-39.1M
Q4 24
$-32.9M
Q3 24
$-38.0M
Q2 24
$-43.7M
Gross Margin
FSLY
FSLY
TWST
TWST
Q1 26
62.5%
Q4 25
61.4%
52.0%
Q3 25
58.4%
Q2 25
54.5%
Q1 25
53.2%
Q4 24
53.4%
Q3 24
54.5%
Q2 24
55.1%
Operating Margin
FSLY
FSLY
TWST
TWST
Q1 26
23.7%
Q4 25
-8.7%
-31.7%
Q3 25
-18.2%
Q2 25
-24.8%
Q1 25
-26.4%
Q4 24
-24.4%
Q3 24
-29.6%
Q2 24
-35.3%
Net Margin
FSLY
FSLY
TWST
TWST
Q1 26
-11.9%
Q4 25
-9.0%
-29.4%
Q3 25
-18.6%
Q2 25
-25.2%
Q1 25
-27.1%
Q4 24
-23.4%
Q3 24
-27.7%
Q2 24
-33.0%
EPS (diluted)
FSLY
FSLY
TWST
TWST
Q1 26
$-0.13
Q4 25
$-0.10
$-0.50
Q3 25
$-0.20
Q2 25
$-0.26
Q1 25
$-0.27
Q4 24
$-0.23
Q3 24
$-0.27
Q2 24
$-0.32

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FSLY
FSLY
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$146.7M
$197.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$977.1M
$456.1M
Total Assets
$1.5B
$638.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FSLY
FSLY
TWST
TWST
Q1 26
$146.7M
Q4 25
$361.8M
$197.9M
Q3 25
$342.9M
Q2 25
$321.2M
Q1 25
$307.3M
Q4 24
$295.9M
Q3 24
$308.2M
Q2 24
$311.8M
Stockholders' Equity
FSLY
FSLY
TWST
TWST
Q1 26
$977.1M
Q4 25
$929.6M
$456.1M
Q3 25
$937.0M
Q2 25
$942.6M
Q1 25
$957.0M
Q4 24
$965.3M
Q3 24
$969.5M
Q2 24
$981.2M
Total Assets
FSLY
FSLY
TWST
TWST
Q1 26
$1.5B
Q4 25
$1.5B
$638.1M
Q3 25
$1.5B
Q2 25
$1.5B
Q1 25
$1.4B
Q4 24
$1.5B
Q3 24
$1.5B
Q2 24
$1.5B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FSLY
FSLY
TWST
TWST
Operating Cash FlowLast quarter
$28.9M
$-24.8M
Free Cash FlowOCF − Capex
$4.1M
$-34.8M
FCF MarginFCF / Revenue
2.4%
-33.5%
Capex IntensityCapex / Revenue
14.3%
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$55.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FSLY
FSLY
TWST
TWST
Q1 26
$28.9M
Q4 25
$22.4M
$-24.8M
Q3 25
$28.9M
Q2 25
$25.8M
Q1 25
$17.3M
Q4 24
$5.2M
Q3 24
$5.0M
Q2 24
$-4.9M
Free Cash Flow
FSLY
FSLY
TWST
TWST
Q1 26
$4.1M
Q4 25
$12.2M
$-34.8M
Q3 25
$22.9M
Q2 25
$15.9M
Q1 25
$14.7M
Q4 24
$251.0K
Q3 24
$3.0M
Q2 24
$-6.7M
FCF Margin
FSLY
FSLY
TWST
TWST
Q1 26
2.4%
Q4 25
7.1%
-33.5%
Q3 25
14.5%
Q2 25
10.7%
Q1 25
10.2%
Q4 24
0.2%
Q3 24
2.2%
Q2 24
-5.1%
Capex Intensity
FSLY
FSLY
TWST
TWST
Q1 26
14.3%
Q4 25
5.9%
9.6%
Q3 25
3.8%
Q2 25
6.6%
Q1 25
1.8%
Q4 24
3.5%
Q3 24
1.5%
Q2 24
1.3%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FSLY
FSLY

Network Services$126.2M73%
Security$38.8M22%
Other$8.0M5%

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

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