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Side-by-side financial comparison of GLADSTONE COMMERCIAL CORP (GOOD) and RHYTHM PHARMACEUTICALS, INC. (RYTM). Click either name above to swap in a different company.

RHYTHM PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($57.3M vs $43.5M, roughly 1.3× GLADSTONE COMMERCIAL CORP). GLADSTONE COMMERCIAL CORP runs the higher net margin — 12.4% vs -83.0%, a 95.4% gap on every dollar of revenue. On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs 16.3%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 10.3%).

Gladstone Commercial Corp is a publicly traded US real estate investment trust focused on acquiring, owning, and operating diversified industrial and commercial properties. It offers long-term net lease agreements to tenants across manufacturing, logistics, healthcare and professional services sectors, mainly serving small to mid-sized business clients.

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

GOOD vs RYTM — Head-to-Head

Bigger by revenue
RYTM
RYTM
1.3× larger
RYTM
$57.3M
$43.5M
GOOD
Growing faster (revenue YoY)
RYTM
RYTM
+20.6% gap
RYTM
36.9%
16.3%
GOOD
Higher net margin
GOOD
GOOD
95.4% more per $
GOOD
12.4%
-83.0%
RYTM
Faster 2-yr revenue CAGR
RYTM
RYTM
Annualised
RYTM
48.5%
10.3%
GOOD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GOOD
GOOD
RYTM
RYTM
Revenue
$43.5M
$57.3M
Net Profit
$5.4M
$-47.5M
Gross Margin
91.6%
Operating Margin
-82.2%
Net Margin
12.4%
-83.0%
Revenue YoY
16.3%
36.9%
Net Profit YoY
-25.1%
-9.6%
EPS (diluted)
$0.05
$-0.73

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GOOD
GOOD
RYTM
RYTM
Q4 25
$43.5M
$57.3M
Q3 25
$40.8M
$51.3M
Q2 25
$39.5M
$48.5M
Q1 25
$37.5M
$32.7M
Q4 24
$37.4M
$41.8M
Q3 24
$39.2M
$33.3M
Q2 24
$37.1M
$29.1M
Q1 24
$35.7M
$26.0M
Net Profit
GOOD
GOOD
RYTM
RYTM
Q4 25
$5.4M
$-47.5M
Q3 25
$4.1M
$-52.9M
Q2 25
$4.6M
$-46.6M
Q1 25
$5.1M
$-49.5M
Q4 24
$7.2M
$-43.3M
Q3 24
$11.7M
$-43.6M
Q2 24
$1.6M
$-32.3M
Q1 24
$3.5M
$-141.4M
Gross Margin
GOOD
GOOD
RYTM
RYTM
Q4 25
91.6%
Q3 25
89.3%
Q2 25
88.6%
Q1 25
88.8%
Q4 24
90.9%
Q3 24
88.5%
Q2 24
89.9%
Q1 24
89.2%
Operating Margin
GOOD
GOOD
RYTM
RYTM
Q4 25
-82.2%
Q3 25
-102.6%
Q2 25
-93.4%
Q1 25
-143.7%
Q4 24
-98.6%
Q3 24
-132.0%
Q2 24
-139.2%
Q1 24
-538.7%
Net Margin
GOOD
GOOD
RYTM
RYTM
Q4 25
12.4%
-83.0%
Q3 25
10.1%
-103.1%
Q2 25
11.7%
-96.1%
Q1 25
13.7%
-151.4%
Q4 24
19.2%
-103.6%
Q3 24
29.8%
-131.2%
Q2 24
4.3%
-110.9%
Q1 24
9.9%
-544.4%
EPS (diluted)
GOOD
GOOD
RYTM
RYTM
Q4 25
$0.05
$-0.73
Q3 25
$0.02
$-0.82
Q2 25
$0.03
$-0.75
Q1 25
$0.04
$-0.81
Q4 24
$0.10
$-0.71
Q3 24
$0.20
$-0.73
Q2 24
$-0.04
$-0.55
Q1 24
$0.01
$-2.35

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GOOD
GOOD
RYTM
RYTM
Cash + ST InvestmentsLiquidity on hand
$10.8M
$388.9M
Total DebtLower is stronger
$843.5M
Stockholders' EquityBook value
$171.8M
$139.1M
Total Assets
$1.2B
$480.2M
Debt / EquityLower = less leverage
4.91×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GOOD
GOOD
RYTM
RYTM
Q4 25
$10.8M
$388.9M
Q3 25
$18.4M
$416.1M
Q2 25
$11.7M
$291.0M
Q1 25
$10.4M
$314.5M
Q4 24
$11.0M
$320.6M
Q3 24
$10.5M
$298.4M
Q2 24
$10.4M
$319.1M
Q1 24
$10.5M
$201.2M
Total Debt
GOOD
GOOD
RYTM
RYTM
Q4 25
$843.5M
Q3 25
$843.3M
Q2 25
$794.4M
Q1 25
$740.7M
Q4 24
$693.4M
Q3 24
$692.6M
Q2 24
$722.5M
Q1 24
$719.4M
Stockholders' Equity
GOOD
GOOD
RYTM
RYTM
Q4 25
$171.8M
$139.1M
Q3 25
$184.8M
$148.8M
Q2 25
$177.2M
$-11.9M
Q1 25
$183.2M
$18.9M
Q4 24
$171.2M
$21.7M
Q3 24
$168.9M
$11.2M
Q2 24
$145.7M
$39.3M
Q1 24
$147.3M
$61.6M
Total Assets
GOOD
GOOD
RYTM
RYTM
Q4 25
$1.2B
$480.2M
Q3 25
$1.3B
$506.9M
Q2 25
$1.2B
$372.7M
Q1 25
$1.2B
$386.7M
Q4 24
$1.1B
$392.3M
Q3 24
$1.1B
$363.6M
Q2 24
$1.1B
$381.8M
Q1 24
$1.1B
$258.7M
Debt / Equity
GOOD
GOOD
RYTM
RYTM
Q4 25
4.91×
Q3 25
4.56×
Q2 25
4.48×
Q1 25
4.04×
Q4 24
4.05×
Q3 24
4.10×
Q2 24
4.96×
Q1 24
4.88×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GOOD
GOOD
RYTM
RYTM
Operating Cash FlowLast quarter
$88.2M
$-25.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
16.38×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GOOD
GOOD
RYTM
RYTM
Q4 25
$88.2M
$-25.4M
Q3 25
$18.9M
$-26.6M
Q2 25
$35.8M
$-23.3M
Q1 25
$17.7M
$-40.4M
Q4 24
$57.0M
$-18.8M
Q3 24
$5.5M
$-25.2M
Q2 24
$13.6M
$-29.1M
Q1 24
$15.0M
$-40.7M
Cash Conversion
GOOD
GOOD
RYTM
RYTM
Q4 25
16.38×
Q3 25
4.57×
Q2 25
7.74×
Q1 25
3.44×
Q4 24
7.93×
Q3 24
0.47×
Q2 24
8.44×
Q1 24
4.26×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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